Chapter II: Preface: To the Second Edition

The text has been revised; the views of physiologists, therapeutists, oculists, and surgeons generally have been brought up to date; those of chemists of the constitution of Cocaine have been epitomized, and pharmaceutical and chemical notes have been added on the modes of dispensing and testing the purity of Hydrochlorate of Cocaine. Being printed in larger type than the first edition, I trust it may be more acceptable to general medical readers.

W. M.

_January, 1892._

CONTENTS.

PAGE
PREFACE iii

INTRODUCTION 1

CHAPTER I.

EARLY HISTORY 2

The accounts given by Cieza de Leon, Nicholas Monardes, Augostin de Zarate, and Joseph Acosta.

CHAPTER II.

SUPERSTITIONS IN REGARD TO COCA 5

Mode of use by the Incas—Von Tschudi on its use in Peru—Pöppig on its use as a viaticum in Huanuco—Effects produced by the Spanish conquest of Peru—Condemnation of its use—Owners of mines encourage its use—Continued increase in production.

CHAPTER III.

COCA IN LITERATURE 8

Unnoticed by modern pharmacologists—Extract from Abraham Cowley, the poet.

CHAPTER IV.

ACCOUNTS OF MODERN TRAVELLERS 10

Von Tschudi, “Travels in Peru”—The custom of masticating Coca—Facilitates mountain ascents and any hard labour—Pöppig on average yield—Intemperate use of Coca—Coca-craving among the Peruvians—Sufferings of _coqueros_.

CHAPTER V.

DR. WEDDELL’S ACCOUNT 15

Mode of cultivation—Amount of crop—Suitable soils—Mode of collection and drying—Mode of use by Peruvians—Description of the leaves—Effects of the leaves—Relief of hunger, a nutriment, effects of habit.

CHAPTER VI.

SCHERZER, FUENTES, AND OTHERS, ON COCA 24

Carl Scherzer’s narrative—Fuentes on its value to miners, travellers, and those exposed to wet and cold—Flores on its use by the Indians of Bolivia—Martius on its use in Brazil—R. Spruce on its use on the Amazon—Fitzroy Cole describes its use in Peru.

CHAPTER VII.

THE CULTIVATION OF COCA 28

Dr. Rusby on its modern cultivation in Bolivia—Quality of the leaves—The harvest—Diseases of the Coca-plants—Mode of drying and exporting the leaves—Probable results of the exportation of the culture to Mexico, East and West Indies, and Jamaica.

CHAPTER VIII.

DR. MANTEGAZZA’S EXPERIMENTS 37

Résumé of its uses and abuse in Peru—Personal experiments—Summary of results.

CHAPTER IX.

BOTANICAL SOURCE AND DESCRIPTION 42

Synonyms, habitat—Description of the plant—Description of chromo-lithograph frontispiece—Practical hints on choosing leaves—Deterioration by exposure and keeping.

CHAPTER X.

COCA IN COMMERCE 46

Report by Hon. R. Gibbs, U.S. Minister—Mode of importation into Europe.

CHAPTER XI.

USE OF COCA AS A RESTORATIVE 48

Resembles Tea in its action—Apt to cause insomnia—Taste, and effects of its use in infusion.

CHAPTER XII.

PHARMACEUTICAL PREPARATIONS 50

Elixir—Extractum Liquidum—Extractum—Infusum—Pastillus Extracti—Vinum—Coca Wine.

CHAPTER XIII.

MEDICAL USES AND REFERENCES 52

Tonic effects—Relief of fatigue—Relief of various diseases and symptoms—Coca-craving—Topical effects—Abstracts from the medical journals.

CHAPTER XIV.

COCAINE AND ITS SALTS 54

Cocaina—Chemical constitution—Mode of preparation—Tests and solubilities—Bougies—Ceratum—Collodium—Emplastrum—Oleatum Oleum cum Cocainâ—Suppositories—Pessaries—Tabellæ—Unguentum—Vaselinum—Cocainæ Citras—Cocainæ Hydrobromas—Cocainæ Hydrochloras—Buginaria—Injectio Hypodermica—Lamellæ—Liquor—Pastillus—Pilula—Tabloids—Trochisci—Cocainæ Salicylas—Dentifricium.

CHAPTER XV.

USES OF COCAINE 61

Local anæsthetic effects—Mydriatic effects, surgical uses—Toxic effects, its mode of action—Diseases for which it is useful.

CHAPTER XVI.

MEDICAL NOTES AND REFERENCES 69