Chapter III: Part 3

_Second day._—10. Heavy sleep, and late waking. Evanescent ideas. Sensation of paralysis immediately after rising, his hand trembles a good deal; he is unable to open the door of his room. Absence of thought. Disposed to be silent. Deep tranquillity of mind, in the morning. 15. Sadness. Drowsy after breakfast. Embarrassed breathing when falling asleep again. Redness of the skin. Sweat in the palm of the hands whereas the rest of the body is perfectly dry. 20. Pain at the lower part of the head, and weight as if he had knocked it against any thing. Small pimples. Beating pain at the left side of the neck. Pain all around the neck like beats with a hammer. Pain at the right side of the head while hearing the strokes on an anvil, he felt as though he were struck with a hammer. 25. Pain at the nape of the neck and forehead when stooping; it is a dull, confused pain which he cannot describe. In the day-time the hands become red. Sense of weight over the eyes. His nose is looser than usual. Pain all round the head as from a blow after having remained in the sun for a time. 30. Redness and heat of the ears. Alternate hunger and loss of appetite. Weak stomach. Loathing. Profuse urine, but always a little white. 35. Acute pain with weight in the pit of the stomach, for a minute. Eructation during an expiration, like a volume of hot air, which ascends to the mouth with a feeling of oppression. Metallic taste in the mouth. White expectoration. Beating pain in the abdomen after breakfast. 40. Disagreeable sensation while hearing the noise of a saw. When hearing blows with a hammer the counter-shock is felt in the whole body. He alternately lays himself down and raises himself again. Swelling of the veins of the hands. Constant pain all day, in the wrist and metacarpus, as if strings were tied round very tightly. 45. Three slight beats on the arm, as if touched with the finger. Easy stool. The face is yellow and the body red. Copious emission of wind. Weak all over in the day-time. 50. Two attacks of colic and diarrhœa, with pulling and pinching in the bowels, at midnight.

_Third day._—Sad, then merry dreams. Every thing is unpleasant to him. The headache continues and renders him impatient. Feeling of tenderness and deep pity. 55. Profuse and whitish urine. The chest dilates a good deal, when drawing breath, even with the mouth closed. The chest feels bruised, with embarrassed respiration. The constrictive pain at the wrist shifts to the middle of the arm for an hour, after which it returns again to the wrist.

_Fourth day._—Lancinating pain in the left temple. 60. Buzzing in the ears, and drumming noise when walking against the wind. Lancinating pain in the chest. Prickings through the heart. The moral emotions are accompanied by an indescribable malaise, beating pain in the chest and loss of speech. When making the least exertion, he is attacked with violent cough and painful prickings in the throat. 65. When commencing to talk, a sudden suffocation and violent beatings in the chest. Suffocation and beatings in the chest when attempting to cough. Beating pain in the head and nape of the neck, with inability to bend the head forwards for the purpose of writing. Weak chest. Thirst every hour in the day-time; desire for water, with aversion to wine or any other liquor. 70. The weakness increases. Sadness. Colic and diarrhœa. Full and frequent inspirations. Urine clear and abundant, but whitish. 75. Lancinations in the bladder when commencing to urinate, he feels relieved after urinating. Pulling and dragging pain in the bowels.

_Fifth day._—Headache. Pain in the chest when making the least motion. The breathing is no longer embarrassed. 80. Extraordinary desire to smoke. Pricking in the feet when sitting. Weakness all over. Pain in the bends of the knees as if bruised. 85. Constriction round the thighs and legs as if a thread had been tied around. Lancinations in the groins. Sexual desire. Continual thirst in the day-time. Dry mouth. 90. Depression of spirits. Sadness. Cold extremities. Profuse and clear urine. Deep sleep in the day-time. 95. Aversion to work.

_Sixth day._—Dream about ghosts and phantoms. Headache. Sad in the morning. Increasing thirst in the day-time, until evening. 100. Heaviness all over. Profuse and clear urine. Loathing of every thing. Aversion to work. Desire to lie down.

_Seventh day._—105. Headache with vertigo, especially in the morning, after eating a piece of bread. Sensation as of a blow in the abdomen, followed by stool. Formication in the right hip, and lancinations when walking. Continual thirst. Sadness. 110. Clear and profuse urine.

_Eighth day._—The urine becomes natural again.

_Ninth day._—The previous symptoms disappear. Active mind, disposed to work. Good appetite.

_Eleventh day._—115. Tetter of an inch in diameter on the left arm; it disappears on the following day. Beating pain in the neck, abating for a few moments by reclining the head. Pricking in the mouth when eating bread. Desire to remain lying. Frequent stool. 120. Swelling of the left ankle. Pricking for two hours at the left knee-joint.

_Twelfth day._—Lancinating pain in the head. Heaviness at the head. Pain at the head after thinking, as from bandaging the head from temple to temple with the skin of a bladder. 125. Confused pain in the head when writing. Lancinating pain in the head, as soon as one sets about eating. Contusive pain at the clavicles, when turning the head right or left.

SECOND PROVING.

_First day._—(The drug was taken at half past seven in the evening.)

One hour after, violent headache, with painful lancinations. The pains continued all night, with sleeplessness.

_Second day._—130. The headache continues, especially at the temples and above the eyes. Acute pain at the elbow-joints. Taste of blood in the mouth. Rheumatic pain at the shoulder-blade. Repeated, violent lancinations in the right side of the abdomen. 135. Lancinations at irregular intervals, in the left shoulder-blade and muscles, from the left side of the chest. Headache all day. Constant dryness in the throat. Taste of blood in the mouth all day.

_Third day._—Painful lancinations in the head, temples, and over the eyes. 140. Intense lancinating pains in the left side. Lancinations in the hypochondria and shoulder-blades. The pain at the elbow-joint continues. Lancination in the right knee-joint. Excessive heaviness and dulness of the head. 145. Constant drowsiness. Incessant headache. Intense, lancinating and constrictive pain in the muscles of the upper part of the right arm, for more than an hour. Continued formication in both feet, especially the left. Taste of blood in the mouth, as if blood had ascended in the throat, and had left the taste of it in the mouth. 150. Frequent and violent lancinations in the abdomen and bowels. Almost complete loss of appetite. Comatose, constantly drowsy. The head feels very heavy, with constant pain in it.

_Fourth day._—No sleep at night. 155. The headache becomes intolerable. Taste of blood in the mouth. Attack of diarrhœa, with pain and tenesmus. First a natural stool, followed by frequent, painful discharges, first of black, fetid substances, then of a watery liquid; the attack lasts upwards of two hours. Lancination in the muscles of the right knee, also in the ribs and right side. 160. Pains in the hypochondria. Lancinating pain in the bowels. Lancinating pain in the left shoulder. The headache continues. Complete loss of appetite. 165. No sleep.

ARRANGEMENT ACCORDING TO HAHNEMANN.

1. MENTAL AND MORAL: Taciturn. Deep repose of mind. Evanescent ideas. Merry. 5. Sadness. Feeling of tenderness. Sad, then merry dreams.

HEAD: Heaviness and dulness of the head. Lancinating pain in the head. 10. Pain at the head, as if bandaged all round, after thinking. Headache with vertigo, after eating bread in the morning. Headache, especially in the temples, and above the eyes. Violent headache with painful lancinations. Pain as from a blow all round the head, when staying in the sun. Weight above the eyes. 15. Pain at nape of neck and forehead, when stooping. Pain and weight at lower part of the head. Lancinating pain in left temple.

FACE, GASTRIC: Face yellow, and body red. 20. Buzzing in the ears. Redness and heat of the ears. Buzzing and whizzing in the ears. Dry mouth. Loathing. 25. Loathing of every kind of food. Loss of appetite. Watery vomiting. Desire to smoke. Thirst every hour, with aversion to wine or liquor. 30. Alternate hunger, and loss of appetite. Pricking in the mouth when eating bread. Eructations, like volumes of air rising upwards. Hot air rises during an expiration. Taste of blood in the mouth. 35. Metallic taste in mouth. Dryness of the throat.

STOMACH, BOWELS: Weak stomach. Acute pain and weight in pit of stomach. Lancinations in the groins. 40. Pulling and dragging pain in the bowels. Sensation as of a blow in the abdomen, followed by stool. Violent lancinations in right side of abdomen. Pains in the hypochondria. Lancinations in abdomen and bowels. 45. Sticking pain in abdomen. Beating pain in abdomen, after breakfast. Flatulence.

STOOL, URINARY, GENITAL: Easy stool. Colic and diarrhœa, with pulling and pinching in the bowels. 50. Diarrhœa, with pain and tenesmus. Natural stool, followed by painful discharges, first of black and fetid, then of watery, liquid substances. Frequent stool. Dartings in the bladder, when commencing to urinate. Profuse urine, rather white. 55. Urine scanty and whitish.

CHEST: Full and frequent inspirations. Weak chest. Contusive pain at the clavicles when turning the head. Sense of heat and trembling in the chest. 60. Suffocation and beating in the chest, when attempting to talk or laugh. Violent cough and painful prickings in the throat, after the least exertion. The chest feels bruised, with oppressed breathing. Lancinating pain in the chest. Considerable dilatation of the chest, when drawing breath. 65. Embarrassed breathing. Prickings through the heart.

BACK, EXTREMITIES: Beating pain at left side of neck, or all around it. Pain at right side of neck as if struck with a hammer. Rheumatic pain at the shoulder-blade. 70. Dartings in the left shoulder-blade and muscles, from the left side of the chest. Beating pain in the neck, abating when reclining the head. Lancinating pain in the left shoulder. Intense darting and constrictive pain in the muscles of the upper part of the right arm. Tetter on left arm. 75. Slight beats on the arms as with a finger. Acute pain at the elbow-joints. Constrictive pain in wrist and metacarpus, all day, shifting to the arm. His hand trembles after rising, as if paralyzed. Sweat in the palm of the hand. 80. The veins of the hand are swollen. Formication in the right hip, and lancinations when walking. Constrictions around the thighs and legs. Bruising pain in the bends of the knees. Pricking at left knee-joint. 85. Dartings in the right knee joint. Swelling of the left ankle. Pricking in the feet when sitting. Formication in the feet.

SLEEP, &c.: Heavy sleep. 90. No sleep at night. Dream about ghosts and phantoms. Constant drowsiness. Deep sleep in the day-time. Red skin. 95. Pimples. Desire to lie down. Aversion to work. Indescribable malaise, with beating pain in the chest and loss of speech. Nervousness, the blows of a hammer produce a counter-shock in the whole body. 100. Beating pain in the head and nape of the neck, with inability to bend the head forwards. Cold extremities. Heaviness all over. Painful dartings in the head, temples, and above the eyes. Darting in the muscles of the right knee, ribs and right side. 105. Weakness in the day-time.

HURA BRAZILIENSIS. (WILLD.)

HURA.—ASSACÙ.—OASSACÙ.

This plant inhabits the equatorial regions of South-America, the provinces of Para, Rio-Negro, and the neighborhood of the Amazon, where it is very frequent. It resembles the hura crepitans; its leaves are alternate, somewhat cordate, rounded, glabrous, serrate; rolled up and stipulate while young. The petiole is provided at its top with two large glands. Flowers monoïchous; the male flowers having a short, urceolate perianth, and covered with a scaly bract; they form elongated, peduncled, terminal husks. The female flowers, which are twice as long as those of the hura crepitans, have their perianth resting against the ovary, which is surmounted by a long and infundibiliform style, terminated by a stellate stigma; they are solitary and placed near the male flowers. It is from this tree that the Indians draw the milky juice called Assacù by the Brazilians.

A man affected with lepra, and who had sought refuge in the solitary regions of the Amazone, took, by the advice of an Indian whom he met there, a considerable quantity of a juice known under the name of Assacù, flowing from the trunk of a tree, which has been described by Willdenow, under the name of hura braziliensis. He was cured; and the president of the province of Para, informed the imperial government of it. Since then, this juice has been very generally used by leprous patients without, however, curing them.

The first and third provers of this drug, on a voyage to Brazil, in 1842, had both been attacked with the lepra. Under homœopathic treatment they seemed both to have got well, though one might have inferred from the gravity of their symptoms, that they had been palliated rather than cured. The frightful symptoms of compression of the spinal marrow, which supervened in the case of one of the provers, point to the Assacù as a powerful remedy for various forms of myelitis. The symptoms of nervous excitement, the twitching, the irritability of the temperament exhibited by all the provers, favor the doctrine that the lepra is a particular lesion of the nervous system. If the exanthems and the insensibility of the skin characteristic of the lepra, have been less marked in our provings, it is undoubtedly because these phenomena belong to some chronic form which a continued use of the drug and a real poisoning are alone capable of producing.

These four provings have been instituted with a single drop of the fifth attenuation. It is our rule to avoid repeating the dose lest the chronological succession of the symptoms which we regard as important, should be disturbed. We do not believe that repeated doses can do much good, and if a prover should not experience any effects from one dose, we should prefer dropping this proving, and resort to some other drug, to which his organism should be more sensible.

First prover: Aug. Joly, 29 years of age, bilious-nervous temperament, healthy constitution.

_First day._—Took one drop of the 5th attenuation at ten o’clock at night.

1. One hour after, itching at the ribs and sternum, at the biceps and the posterior parts of the right arm. Doughy mouth, in the morning, on waking. Dreams about a ball, about houses in process of erection. In the morning, itching at the arms, legs, outer parts of the tibia. 5. The upper and lower eyelids are inflamed and blueish. Itching at the right arm, at the lower and inner portion of the humerus, owing to a little pimple which is forming. Taste of blood in the mouth. Whizzing in the ears, especially the right. Clusters of miliary pimples on the back, arms, legs and chest. 10. Irritated by the least contrariety. Desire to vomit, sick stomach. Rheumatic pain at the left arm. He looks weary as if he had been carousing all night, though he slept well all night. Pinching at the right side of the tongue. 15. Lancination in the canal of the urethra. Prickling around the eyes, and especially around the right one. Sensation as if small pimples would break out on the inside of the eyelids. Nervous beating in the eyelids. Rheumatic pain at the sacrum, especially when stooping. 20. Contusive pain at the lumbar region. Miliary eruption in the joints.

_Second day._—Dry mouth in the morning. Acute pain in the lumbar region and at the sacrum, as from a fall. Smoky taste of the water which is drank at breakfast. 25. Pain in the ileo-femoral articulation. Pain all along the left thigh. Sneezing, and frequent blowing, as when a catarrh is about setting in, followed by involuntary discharge from the nose of a lemon-colored mucus, with tickling. Constant pain in the lower part of the lumbar regions, worse when stooping or sitting down. Lancinating pain at the top of the head. 30. Slight desire to vomit at eleven o’clock in the morning. Dizziness. He dreams that he was swimming in a river with warm and dark-green water; afterwards that he was on a plantation in Brazil, where men drew water from a yellow pond. Moist, intermittent heat, mounting every fifteen minutes from the feet to the face. Prickling at the right eye. 35. Sense of heat mounting to the clavicles. (At a quarter of ten o’clock:) Dry nose, he cannot blow it; with itching at the interior of the nose.

_Third day._—In the morning, the pain at the sacrum had disappeared. (At ten o’clock and a half:) The pain at the sacrum returns worse, after moving a box. Burning at the right index-finger, a red spot extending from the nail to the second phalanx. Numbness; almost amounting to insensibility. 40. (At half past twelve:) Pain as from a splinter under the thumb-nail. In the evening, tickling under the arms and along the dorsal spine. No sleep at night, frequent waking, feverish agitation.

_Fourth day._—Heat in the hands, in the morning. At two o’clock, a small vesicular pimple on the back of the left hand; for four hours. 45. Stiffness in the trapezoid muscle, near its attachment at the occiput. Pain at the left forearm as from a blow. Small vesicular pimples, and itching at the ribs, arms, and at every prominent process of the bones.

_Fifth day._—In the morning, the pimples on the arms have almost disappeared; there remains only a little itching at the sternum. Heat at the tips of the right fingers. 50. Sensation as if a small portion of the nail of the right index-finger had become detached. At half past six in the evening, heat and passing sweat. At half past seven in the evening, sensation of burning, smarting on the left side of the chin, in the beard, as from an incipient tetter. Sensation under the masseter muscle, as from a recent blow on the parotid. At eight o’clock in the evening, the spot becomes sensible to contact; a small swelling is observed extending below the zygomatic arch. 55. Sensation at the supinator muscle of the forearm, as from an incipient tetter. Small pimples on the inner surface of the lower lip. Stiffness of the trapezoid muscle and the neck. Prickling as from dust, at the border of the lower lid of the right eye. 60. Itching at the back, legs, arms, at the same time.

_Sixth day._—Fleshy excrescenses on the inner surface of the lips. At four o’clock, weariness in the legs, in going up-stairs. At eight o’clock in the evening, painful stiffness of the neck. The pain in the masseter muscle, which had already decreased in the morning, disappeared entirely in the evening. Weight in the testicles in walking, at five o’clock in the evening. 65. Taste of blood in the throat before breakfast.

_Seventh day._—Itching at the right lower eyelid, as if a pimple would appear. At three o’clock, sensation as of dust in the left eye. Sense of weight at the eyes, as if they had been strained.

_Eighth day._—No sleep all night. 70. Pressive pain at the cranium. Heat in the nails of the left hand.

_Ninth day._—Straining sensation in the upper part of the sacrum, preventing him from standing erect, at noon. Taste of blood in the throat before breakfast. Sputa mixed with blood. 75. Sense of giving way in the knee-joint, in going down-stairs, at two o’clock. At four o’clock, pain in the renal region, which keeps increasing; it decreases at five o’clock. Prickling in the left eye, and intolerable itching, with nervous irritation which spreads to the heart, but passes off soon.

_Tenth day._—Prickling in the left eye as from dust. Smarting sensation in the beard as from a pimple at each hair, at nine o’clock. 80. Burning sensation at the inner canthus of the right eye, at half past nine in the evening. The carunculæ lachrymales look inflamed.

_Eleventh day._—Itching at the anterior surface of the tibia, at night, and smarting sensation as from a tetter. Appearance of a small red circle, with a small dark-red pimple in the middle; followed by peeling off. Itching at the hairy scalp, especially behind and in the mastoid process, as from a tetter. 85. Sensation as if he had torn off a hang-nail, or as from a splinter in the ring-finger of the left hand. At ten o’clock, smarting at the bend of the right elbow, on the outside.

_Twelfth day._—Tickling at the left arm, with small vesicular pimples. Itching in the beard, with small pimples which form a crust under the chin. Itching and small crusty pimples on the hairy scalp. 90. Constrictive sensation at the anus; at half past five o’clock.

_Thirteenth day._—Painful sensation at the upper and lateral portions of the sacrum, as if strained or bruised. Clusters of small miliary pimples at the bend of the elbow, with redness around the pimples after scratching them. The pimples cease to be vesicular; other pimples appear on the insteps. Prickling sensation in the eyes all day, with redness and smarting at the border of the lids. 95. Sensation as if there were dust or foreign bodies in the eyes. The right eye is more sensible than the left. Weariness in the legs, after noon. Pain in the left knee as from a sprain, with lancinations below the pain.

_Fourteenth day._—Contractive sensation below, and at the right side of the coccyx. 100. Rheumatic pain at the left side of the neck, the splenius, complexus and trapezoides muscles.

_Fifteenth day._—Rheumatic pain at the neck, with difficulty of turning the head to the left side, in the morning. Pain in the head like a weight on the skull, extending to the mastoid processes. Sense of loathing with nausea. Oppression at the stomach when standing erect. 105. Pale face, with rings around the eyes and redness at the margin of the eyelids. Pains in the head like a beating in the sides and at the vertex, reverberating in the mastoid processes, and extending to the sterno-mastoid muscles. Sense of constriction in the upper part of the throat. Yellowish, heavy and frothy expectoration, ever since he took his drug. The affective sphere is very active. 110. Painful stiffness of the neck, which prevents one from turning the head to the left side. Sensation, in closing the eyes, as though the eyelids were cold. Pain from the occiput to the vertex, with beating, and acute pains.

_Sixteenth day._—Horrid pain in the sacro-lumbar region, at the articulation of the last lumbar vertebra and sacrum, when attempting to raise a weight. Pain as when straining a ligament; numb pain in the left thigh, along the course of the sciatic nerve. 115. Inability to stoop without experiencing acute pains in the sacro-lumbar region; he is obliged to lie down. Fainting when trying to sit down, caused by the violence of the pain at the sacrum; sense of tearing. Nervous spasms, convulsions, cramps in the calves and toes during the fainting spell. Sense of shuddering at the rectum. Tickling like worms creeping along in the rectum. 120. In spite of the pains, he slept pretty well in the night, from the fifteenth to the sixteenth. Desire to urinate, every half hour. He urinates a long time. Watery urine, with a greenish tint. Cramp in the right middle, and ring-finger. 125. Pulse interrupted for two minutes, ringing in the ears, roaring in the head, beating in the temples. During and after the fainting-spell disposition to love everybody, especially those around you. He often thinks of death, but he is not afraid of dying; he even feels as though he would die without regret. He reproaches himself with everything bad he has done, even the least trifles, and considers himself very guilty for having done them. During the nervous attacks, he thinks of his salvation. The sense of smell is very acute, he even smells persons at a distance.

_Seventeenth day._—130. The pain at the sacrum seems to decrease, but he is not yet able to rise from bed, nor stir about in it, he has to remain lying on the back. He has an appetite, but eats little. A sort of painful glandular swelling behind the masseter muscle, below the right ear. Dulness of the head, in front. Sense of oppression at the forehead.

_Eighteenth day._—135. Frequent waking at night. He wakes earlier than usual. Doughy mouth, in the morning. Foul, bloody sputa, of the color of chocolate with milk. The pain at the sacrum is feebler, it seems to have spread over a larger space, rises a little towards the dorsal and lumbar muscles, and to the dorsal vertebræ. 140. The head, above the eyebrows, is still somewhat dull. Weakness in the finger-joints and wrists. The gland at the neck continues painful, with lancinations. Taste of blood in the throat. Flushes of heat. 145. The breathing is painful, as if there were a sore in the lumbar region.

_Nineteenth day._—Deep and long sleep. Nosebleed, in the morning. Pimple at the forehead. Weight above the eyes, he is unable to read long. 150. Sense of weariness in the arms, though lying down. The pain at the sacrum decreases; sometimes, however, it rises again to the cervical vertebræ. Prickling in the eyes. A cluster of pimples breaks out at the wrist, on the external and inferior surface of the radius; they are vesicular, (like those which he had after his return from Brazil.) Bloating sensation in the eyes. 155. Throbbing at the sacrum, without pain. Pale face, eyes sunken, with redness around the eyelids.

_Twentieth day._—No stool from the sixteenth to the twentieth day. Hard and difficult stool. The pain at the sacrum is much less, though he still feels a violent throbbing in this region, but painless. 160. Rose at eight o’clock, his legs were weak and his head felt heavy; he laid down again an hour after, with very cold feet. He feels a pain at the iliac bones, though not all the time. There are fever pimples on the arm, and the remaining pimples contain a little water which spirts out when pressed. Sensation in the glutei muscles as if bruised. Full and slow painless beatings in the sacro-lumbar region.

_Twenty-first day._—165. Restless night, dreams about crime, dead bodies, children with their heads half cut off, and of others whose heads were being cut. Pain in the glutei muscles as if bruised, now on the right, then on the left side. Pain as if bruised at the sacrum, with heat mounting to the face, at nine o’clock in the morning, shortly after rising. Cramp in the toes. Beatings in the left temple. 170. Painful stitch and beating sensation between the shoulder-blades.

_Twenty-second day._—Lascivious dream with emission. Heat mounting to the face, with oppression of the chest. Acute pain in one of the right toes. Weight at the sacrum, but less bruising in the glutei muscles; weakness in the knee joints, with cracking, either in going up or down-stairs, 175. Sensation as if a warm liquid were flowing from a sore in the lumbar region. Heat mounting to the face, at seven o’clock in the evening. Weakness of the legs in going up or down-stairs.

_Twenty-third day._—Restless night, heat and sweat all night. Dream about work, vast business. 180. Dizziness at two o’clock, waves before the eyes; the sight becomes dim when writing. Sparks and zig-zag movements before the eyes, when walking or sitting. Weak legs. Weight in the upper lids. Frontal headache. 185. Pressure at the forehead, with damp coldness at the feet and hands. The headache extends to eyebrows and eyes. Short-lasting oppression at the throat, in the region of the tonsils. The eyes are red, with blue dark margins; face pale, yellow, dull. Less pain in the renal region; but he is unable to stand any length of time without experiencing an uneasiness in the stomach which extends to the chest with oppression. 190. Sclerotica red, inflamed, and the capillaries injected. Beating pressure at the sclerotica. Weakness of the knee-joint, when walking or going up and down-stairs. Hiccough four hours after eating.

_Twenty-fourth day._—Restless sleep. 195. Slight prickling pain at the sacro-lumbar articulation, in going up-stairs. Sense of oppression at the chest.

_Twenty-fifth day._—Pressure at the forehead. Heat in the sacro-lumbar region; sense of oppression at the chest, and rush of blood to the larynx, with suffocative oppression; taste of blood and tearing in the chest.

_Twenty-sixth day._—Restless sleep. 200. Throbbing and weakness in the sacro-lumbar region. Nausea while riding in a carriage, before breakfast. Sense of heat in the renal region, after a long ride in a carriage. Slight aching pain at the forehead and vertex.

_Twenty-seventh day._—Restless sleep. 205. Beatings in the lumbar region, with slight pullings or shudderings. Weakness in the lumbar region. Weakness in the knee-joint; sense as if sprained, after a walk.

_Twenty-eighth day._—Restless sleep, with dreams about work, wild beast devouring meat in a public slaughter-house. Sense of heat with throbbing and fatigue in the lumbar region and above the iliac bones. 210. Paleness, cold hands and feet, with weakness all over while the pains last.

_Twenty-ninth day._—Dream about revolution, gun-shots, demolition of some public edifice; he walked among the ruins. Sense of well-being, in the morning on rising. Doughy mouth every morning, with sputa that has the color of chocolate with cream, and fœtid smell. Spits blood in the morning that seems to come deep out of the throat. 215. Swelling of the left lower gums, over the molar teeth, outside, with toothache in this region. Small pimples on the right knee, with smarting as from a tetter and painful itching when touching them; they emit a fluid when pressed upon; itching at the tibiæ.

_Thirtieth day._—The swelling of the gums continues, but the toothache is less. The cheek threatens to swell. Taste of blood in the mouth and throat, very marked, with scratching or tearing sensation when drawing breath. 220. Headache at two o’clock, as from a nail in the vertex, with violent toothache, swelling of the gums, after a walk. Beatings in the left side of the face, extending up to the eye. The feet, and mostly the whole body are constantly damp and cold, with weakness. Uneasiness at the stomach. His breakfast does not seem to sit well on his stomach; he eats with a good appetite, however (from the twenty-fourth day).

_Thirty-first day._—Restless night. Intolerable erections, sexual dreams, with emissions. 225. Large pimples on the legs, around the root of each hair. In the evening, large pimples, swollen, like mosquito-bites, with violent itching, and raw feeling when touched.

_Thirty-second day._—Weakness, with painful stitch in the lumbar region. Uneasiness in the stomach, every day after the noon-meal. Violent headache on the left side.

_Thirty-third day._—230. Sense of tearing and spraining in back when sitting (for one minute). Spitting of blood, with sense of rawness in the throat and the respiratory passages, after talking. Contractive sensation on the skin of the forehead. Pimples all over the body, similar to those above described; suffocative sensation rising to the larynx.

_Thirty-fourth day._—Taste of blood in the mouth during an embrace. 235. General emaciation. Inability to incline forward; he can only walk by reclining the trunk backwards; when inclining forward ever so little, he feels a pulling in the lumbar region and is obliged to straighten himself.

_Thirty-fifth day._—Uneasiness at the stomach from the noon-meal until four in the afternoon. Irritable mood.

_Thirty-eighth day._—Frequent desire to urinate. 240. Clear urine, after a return of the pain in the sacro-lumbar region. Tearing sensation in the renal region; acute pain, with faint feeling and pale face.

_Forty-sixth day._—Cold sweat at night.

_Fifty-fifth day._—Pale, sickly face; rings around the eyes. Red lips. 245. Emaciation. Weakness in the sacro-lumbar region. Dimness of sight, and prickling in the eyelids. (From this period, he gradually gets better.)

Second prover: Chr. Dieudonné Joly, twenty-four years old, sanguine-nervous temperament, robust constitution.

At eight o’clock in the evening, took one dose of assacù of the fifth attenuation.

_First day._—Contraction of the papillæ on the tongue, immediately. 250. Heaviness of the head. Acute pain in the right kidney while walking, with urging to urinate, at nine o’clock in the evening; for two minutes.

_Second day._—In the morning, while walking, pain as if sprained in the left coxo-femoral articulation, for some moments. Prickling at the margin of the eyelids, in the day-time. Face looks weary, with rings around the eyes. 255. Lancinations in the left index and thumb. Dull lancinations in the right hand. Itching at the left side and calf. Stitch in the right index-finger at eight o’clock in the evening. Feeling as of sand in the left eye, at ten o’clock.

_Third day._—260. Nocturnal emission. Sneezing at noon, as when a catarrh is about setting in. At two o’clock, dark redness and almost complete insensibility of the sides of the neck in the region of the sterno-cleido-mastoideus-muscles; he pricks the parts and does not feel any pain until one hour after.

_Fourth day._—No sleep at night, and drowsy in the day-time. Livid complexion at noon. 265. At nine o’clock in the evening, itching at the left eyelids.

_Fifth day._—Violent nosebleed, at seven o’clock in the morning. Stinging in the ball of the right thumb. Slight pain in the medius of the left hand.

_Sixth day._—Itching at the margin of the left eyelids. 270. At noon, pimple at the right lower part of the lower jaw. At ten o’clock in the evening, in bed, smarting and itching of the puncta lachrymalis and the left lower eyelid.

_Seventh day._—At two o’clock: Aching pain like a stitch in the side, under the right lower ribs, for one minute.

_Tenth day._—At three o’clock in the afternoon, slight colic, and nausea. Dull and heavy head, with weak legs.

_Eleventh day._—275. At eleven o’clock, hypochondria, sadness, despair; he imagines that he is abandoned by his family.

_Twelfth day._—Fatigue, and weakness of sight.

_Thirteenth day._—Eyes red, with weak sight, he reads with difficulty. The upper and lower limbs feel weak.

_Fourteenth day._—Eyes weary, sight weak. 280. Short, dull, painful lancinations in the pectoral muscles, rather internal, without impeding the breathing.

_Fifteenth day._—Weariness of the eyes, pressure at the superior portion of the orbits. Headache. At nine o’clock in the evening, lancinating pain in the biceps and triceps muscles of the arm, similar pain between the shoulder-blade and the spinal column, in the trapezoid muscle. The throat feels dry and irritated, compelling one to cough. 285. Dryness of the glottis; causing a cough as from a cold.

_Sixteenth day._—Itching at the margin of the eyelids.

_Seventeenth day._—Sense of stoppage in the ears; afterwards as if air-bubbles were passing through the left ear (for two or three seconds). Small smarting pimples on the lower part of the right leg.

_Twenty-third day._—Diarrhœa.

_Twenty-seventh day._—290. Nocturnal emission. Weight at the frontal muscle. Heat about the head. Painful stitch in the ileo-cœcal region, recurring several times when walking or moving about. Slight nausea.

_Thirtieth day._—295. Pain as from weariness in the outer portion of the left crural muscle when pressing upon it.

_Thirty-first day._—This pain is very marked and continues all day.

_Thirty-second day._—Violent headache in the left side of the head.

_Thirty-third day._—Headache in the side of the head.

_Thirty-fourth day._—In the evening, slight pain in the lumbar muscles as from weariness.

_Thirty-fifth day._—300. The weariness in the loins continues in the morning. At 9 o’clock in the evening, slight pain as from weariness, with an acute lancination in the lumbar region, for one second.

_Thirty-sixth day._—At noon, long-lasting lancinating pain under the left big toe. A good appetite for some days past.

_Thirty-seventh day._—305. Hard, scanty and difficult stool. Absence of mind. Not disposed to work. Peevish. Red eyelids. 310. Lazy, weary. Constant yawning.

_Thirty-eighth day._—Hungry, two hours after a copious meal. Tightness at the stomach, in the evening.

_Thirty-ninth day._—At five o’clock in the morning, violent sensation of hunger, with tensive and pressive pain at the stomach; when lying, the pain extends to the umbilical region. 315. The pain during a walk continues; pressure after eating; painful sensation of hunger. Acute pain at the stomach, with constant hunger. Frequent desire to urinate. The urine deposits a white sediment. At noon, pressive pain at the stomach, before and after eating. 320. Acute pain, like a stitch, at the anterior surface of the right lung, which hinders breathing. Absence of mind, he makes many mistakes, mistakes one month for another, for several days. He mistakes the street twice. During the last days of the proving, frequent urination with whitish deposit.

Third prover: Mme. Al. j., 26 years old, sanguine temperament, good constitution.

_First day._—Took one dose of the 5th attenuation, at 10 o’clock in the evening.

In the morning on waking, doughy taste in the mouth, and great drowsiness. 325. She dreams about death, burial. Small painful pimples on the left side of the tongue. Burning at the stomach. Stiffness at the nape of the neck. Weakness of the legs and arms. 330. Nausea at two o’clock. Fever: face of a scarlet-red, hands burning-hot. Depression of spirits, has no desire to do any thing, nothing pleases him. White spots on the tongue. Frequent desire to urinate. 335. Feeling of weariness all over. Sense of pain with heat at the sacrum.

_Second day._—Lancinating pain, zig-zag, in the uterus, at half past six in the morning. Slight leucorrhœa. Dry cough. 340. Pain in the groin, compressive sensation as during parturition. Lancination from the lumbar region to the coccyx.

_Third day._—Restless night, frequent waking. On waking, sense of weariness, as if strained. Acute pain in the palm of the left hand, proceeding from the index, and describing a circle extending to the carpal articulation of the thumb. 345. Very weary, especially the left leg. At half past 12, third night, writhing colic. Violent diarrhœa at one o’clock, with pains similar to those which she had experienced on her return from a voyage to Brazil. Fetid stool, with white little worms. 350. The diarrhœa continues and is succeeded by a great weakness of the chest. Violet-colored cheeks. Heat in the cheeks and temples. Red forehead. Small miliary vesicles on the right cheek, on the middle of the forehead and on the left cheek. 355. Listless, she attends to things as if she took no sort of interest in them.

_Fifth day._—Dreams about a church-yard; she placed torches on the graves. On waking, her face is bloated and scarlet-red. Blotches on the right cheek, similar to those which she had after her return from a voyage to Brazil (at this time an enormous crusty tetter commenced in this way). Intolerable heat at the chest, at two o’clock, violent pain and burning sensation at the sternum.

_Sixth day._—360. Restless sleep. Nervousness, impatience, at half past 12. Dry heat in the hands.

_Seventh day._—Small vesicular pimple at the right wrist-joint. Marked feeling of heaviness from the parietal bone to the lower attachment of the sterno-mastoideus muscle, at the upper side of the sternum. 365. At two o’clock: the weight, at times, descends to the forehead, with heat. Small pimple on the right wrist, red at its base, containing a fluid.

_Eighth day._—No sleep. Twisting pain in the left side, or lancinations around the pelvis; the pain passes off soon and extorts cries from her, at 9 o’clock in the morning. Burning all over.

_Ninth day._—370. Twisting pain at the scapulo-humeral articulation. Acute pain under the breast. Half past twelve: the pain at the scapulo-humeral articulation recurs from time to time with great violence. Five o’clock in the evening: the pain is constant but less, always of the same kind. Half past nine: miliary eruption in the face. 375. Small red pimples on the right cheek, smarting on the right cheek, the eruption first showed itself at 7 o’clock in the morning. Miliary eruption on the shoulders, with itching, in the evening. Red vesicular pimples, they break when pressed upon, and discharge a smart stream of water.

_Tenth day._—Dulness of the head, in the morning, on rising. Red face, the little pimples are less apparent. 380. Pain at the stomach, as from hunger, though she is not hungry. She swallows her saliva. She has to eat to quiet her pain.

_Eleventh day._—Headache, slight beating at the forehead, during a considerable portion of the night. The headache continues with a heaviness in the forehead, in the morning.

_Twelfth day._—385. Small pimples on the back, with itching. Nosebleed, at 8 o’clock. Hard stool for 8 days. Nosebleed, at 10 o’clock.

_Thirteenth day._—390. Restless night, dream about a sea-voyage. Heaviness of the head, nosebleed on rising. Headache, heaviness with beating in the forehead, all day. Red pimples on the shoulders, with pricking when touched. Lancination and pricking in the left little finger, three or four different times.

_Fourteenth day._—395. Hot and red face. Itching red pimples on the shoulders.

_Fifteenth day._—Sense as of crumbs in the eyes. Sclerotica red, with margins around the eyes, red eyelids, red face. Red pimples on the sides of the hips, smarting.

_Sixteenth day._—400. Sharp pain, followed by an acute lancinating pain about the heart.

_Seventeenth day._—At eight o’clock in the morning, sharp, lancinating pain, by fits and starts, at the right side of the sacrum, more or less violent. Ten o’clock in the evening: wry neck on the right side.

_Eighteenth day._—While slumbering, sensation as if she were hanging three feet from the ground. Sensation as if she would fall into a ditch. 405. Coldness and heat, alternating at night.

_Nineteenth day._—Acute pain at the left hip, at 9 o’clock in the morning. The pain recurs at 9 o’clock in the evening, and continues for several days at the same hour. Pain at the uterus as if compressed. Pain at the heart, which is at times very sharp, almost unbearable. 410. The breathing is arrested; this pain makes her very uneasy. Lancinating pain in the head.

_Twentieth day._—Pain at the left knee, as if sprained.

_Twenty-first day._—Writhing colic, and diarrhœa, five times in the day.

_Twenty-second day._—Restless night. 415. In the evening, pain at the loins and on each side of the ovary. Violent lancinations with prickling, afterwards lancinating pain in the vagina; appearance of the menses, but very slight.

_Twenty-third day._—Pain in the uterus as if a sharp instrument were thrust in. Lancinating pain above the left breast. Pain at the right little toe, like an intermittent throbbing, with intolerable prickling, at half past 10 o’clock in the evening.

_Twenty-fourth day._—420. Sleep disturbed by a violent itching caused by small pimples on the shoulders. In the morning, the pain of the little toe returns, but it does not last as long as the day previous. Pain in the renal region, with sense of weariness in the region of the sacrum. Cold and heavy pain at the left hip. Painful pricking in the wrist and along the left hand, between the middle and ring-finger.

_Twenty-fifth day._—425. Prickings and stitch above the left breast, hindering breathing, whether walking or sitting. Acute pain when drawing breath.

_Twenty-sixth day._—Sense as if sprained in the left knee and cracking when walking.

_Twenty-eighth day._—Restless night. Desire to cry. 430. Fever, inability to close her hand. Sad, vexing thoughts.

_Twenty-ninth day._—Sensation as if floating in the air. No sleep. Starting in bed. 435. Sensation as if she were falling to the ground. Lancinating pain under the heart; it continues, more or less feeble. Bad digestion, the stomach feels yet full since supper.

_Thirtieth day._—Restless night, starting during sleep. Sense of weariness in the lumbar region, all night. 440. Pain at the sacrum as from a recent blow, this pain increases until four o’clock in the evening. Pressure at the sacrum, with weariness in the left thigh. Heaviness at the sacrum, when sitting. Sensation as if worms were crawling in the posterior and external portion of the sacrum.

_Thirty-first day._—The pain at the sacrum obliges her to keep bent; this pain shifts up and down from the sacrum to the left thigh, and is accompanied by chattering of the teeth, which interrupts the speech, and by cold hands and feet. 445. Quickly-passing tingling and twisting pain in the right leg, at three o’clock in the evening, when lying. Twisting pain extending from the sacrum into the left leg, and obliging her to lie down. Every paroxysm of pain excites a nervous laugh, with moanings like those of a sick child. Sensation as if dogs had bitten her where the pain is felt. Sensation as if she had a plaster at the region of the kidneys. 450. The pain descends along the vastus externus muscle. Mottled face, in the beginning of the proving it became red, now it is sometimes pale. She cannot walk, without fearing to fall. No solicitude for the future, generally speaking; tears with ennui; she thinks of death without fearing it. The pain at the sacrum is worse when sitting, and obliges her to lie down.

_Thirty-second day._—455. Sleep during the night, but the pain in the renal region returns as soon as she rises from bed. The pain is seated in the sacro-lumbar articulation; it extends to the glutei muscles with sensation as though she were gnawed by dogs. At times the right thumb feels numb.

_Thirty-third day._—Pain in the vertebral column. Sense of luxation, with pain in the glutei muscles, of the same nature as the day previous.

_Thirty-fourth day._—460. Twisting sensation in the groin. Nosebleed, when lying. Vesicular pimples all over, with red spots as if the skin had been rubbed. Large blotches on the legs like mosquito-bites. Sensation in the renal region and buttocks as if gnawed by dogs. 465. Continual sneezing for two hours.

_Thirty-seventh day._—Sensation in the thighs, as if bitten by dogs. The pimples increase during an increase of temperature, and leave large red spots in the renal region and on the hips. Since she had the pains in the sacrum, she is unable to sleep or rest on the stomach.

_Thirty-eighth day._—Uneasiness, sometimes she cries in the street. 470. Acute headache, like a circle which rolls quickly over the forehead. Dizziness. Profuse nosebleed from both nostrils. The nosebleed is preceded by a smell of blood. Red face, with little pimples between the skin and flesh. 475. Heat at the face. Sensation as if the skin of the face were stretched too much. Frequent emission of watery urine. Sense of coldness in the right-thigh.

_Fortieth day._—480. Dreams about dead bodies, assassins, decayed oxen, yellow water. Continual nosebleed, especially in the morning. The pains in the renal region decrease.

_Forty-third day._—Nervous twitching at the left lower eyelid.

_Forty-fifth day._—Flow of sad thoughts; she imagines she will lose somebody who is dear to her. 485. She cries every moment, and, for several days past imagines she is seeing the dead person before her eyes.

_Fifty-eighth day._—Painful sensibility of the whole right half of the head, especially when touching it. Lancinations in the jaws, pain at the right arm. Impatience, anger; she bites her hands, and gets mad because her ideas flow too slowly.

Fourth prover: Mlle E. R. 17 years, sanguine temperament, good constitution. 490. At 8 o’clock in the morning, the ball of the thumb of each hand is painful. 9 o’clock: her feelings are excited and she cries a good deal. 10 o’clock: numbness of the right index, every minute. Half past 10: cold and clammy feet, followed by heat for three hours. Half past 11: short lancinations in the last two left molares, lower jaw; numbness in the bend of the right arm. 495. Lancination in the right index-finger, and especially in the articulation of the last phalanx. Sensation of a small ball under the left breast; at the same time, lancination under the left shoulder, for 5 minutes. At noon, large red spot on the lower part of the left cheek. Half past 12: heat at the face, for half an hour. Half past 12: small pimples on the left cheek, above the nose and near the lower lip; they are red, with a small white point in the middle. 500. At two o’clock, beating in the right index-finger. At half past 2, lancination in the gums. At a quarter past four; pain in the gums corresponding to the left eye, with heat in the face. Burning in the left cheek, weight at the eyes, lancinating pains in the ears. Pain at the outer ankle, as from a blow. 505. Frontal headache, at half past 9 in the evening. Cold sweat on the face. Pressure in the orbits, as from a violent headache. The teeth and gums are painful when pressing the teeth against each other; the pain extends to the nose. Toothache on the left side.

_Second day._—510. Half past seven, white-coated tongue. Slight pain shifting from the left ear, where it commenced, to the left orbit. Small pimple at the inside of the left elbow, causing a smart itching. Half past 7, lancinations in the right side, every second. Cold feet. 515. Eight o’clock, pain as if the right arm had been stretched a long time, contusive pain at the back of the right hand, especially at the middle-finger. Lancinations in the gums on the right side. Itching at the forehead. Small pimples at the forehead. Suffocative oppression in the chest, especially when thinking of any thing contrary. 520. The oppression ascends and immediately after descends again. Heat mounting to the face. Pain at the sternum. Lancinations in the temples. Pain in the gums on the left side. 525. Discouraged, does not wish to do any thing. Weight at the arms. Suffocative oppression in the chest. Ten o’clock in the evening, pain in the orbits as from a violent headache, or as from looking fixedly at the same object.

_Third day._—Half past 6 in the morning, the right cheek is quite swollen, without toothache. 530. Red pimple on the left cheek, in the middle, and on the left side of the neck, with a good deal of itching. Nine o’clock, beating at the right side of the thorax, almost under the shoulder. Half past 3, pain at the right wrist; all the veins and fibres hurt her. Half past 8, oppression at the stomach. Twisting colic. 535. Nine o’clock, heat at the face. Half past 10, desire to cry. Since taking the drug, the least thing irritates her; at such times she feels oppressed, with desire to cry, she blushes, sighs a good deal, several times a day. Less appetite. Pain at the chest, especially the left breast, when lying; the pain gradually passes to the right side.

_Fourth day._—540. Since the first day, she wakes sooner than previously; her sleep was heavy and she was unable to open her eyes. Now she opens them easily, and the ideas come to her at once. Half past 5, shuddering all over, she feels oppressed, wants to cry. Colic, with cold feet. Eight o’clock, the shuddering extends over the legs; she feels oppressed and has cold feet. 545. Nine o’clock, prickling at the tongue on the left side, causing a good deal of water to accumulate in her mouth. Nervous pain shifting speedily from the orbits to the forehead, and disappearing at once. She sighs a good deal. Ten o’clock, she feels sick at the stomach, as from hunger, generally she is not hungry till noon. Hungry, sometimes shortly after a meal. 550. Pain as from pressing strongly on a sore behind the right ear, and under the neck, at the larynx; pain when moving the head. Cold feet, at 10 o’clock in the morning. Hunger, with pain in the stomach, at 11 o’clock. Tightness at the root of the nose, for an instant. Short lancinations all over the face, with tightness of the head emanating from the temples. 555. Slight contusive pain under the false right ribs.

_Fifth day._—At noon, oppression hindering breathing. Oppression in the chest, causing her to sigh a good deal. Numbness of the head. The face, and head, from the vertex, pain her horribly. 560. Contusive pain between the ring- and little finger, only for a moment; reaching up to the elbow. Tightness at the back of the head. Pain as from weariness in front of and behind the neck. Frequent desire to urinate. The left cheek is very red. 565. Redness of the wing of the nose. Shuddering along the back and legs while taking breakfast. At 5 o’clock, oppression and sighs. Pain in the ear, and half of the jaw, followed by pricking in the ear. At a quarter past 5 o’clock, colic and shuddering. 570. At 8 o’clock, pain as from weariness between the shoulders. At 9 o’clock, oppression on the chest. She sighs a good deal. Internal trembling. Cold sweat on the feet. 575. At half past 10, red blotch on the right shoulder; hot feet, after lying down, in bed.