Chapter III: Preface: iii-iv

CHAPTER I

HISTORY OF SCURVY 1

(_a_) OUTBREAKS ON LAND; (_b_) OUTBREAKS AT SEA; (_c_) INFANTILE
SCURVY; (_d_) SCURVY IN THE WORLD WAR

CHAPTER II

PATHOGENESIS AND ETIOLOGY 23

PATHOGENESIS: THEORIES; POTASSIUM DEFICIENCY; ACIDOSIS; TOXIC;
BACTERIAL; VITAMINE (ACCESSORY FACTOR)

ETIOLOGY: BREAST-FED INFANTS 35

ARTIFICIALLY FED INFANTS: PASTEURIZED MILK; BOILED AND STERILIZED
MILK; DRIED MILK; CONDENSED MILK; PROPRIETARY FOODS (EFFECT
OF ALKALIZATION) 40

AGE, SEASON AND CLIMATE; ECONOMIC STATUS; PSYCHIC ELEMENT;
PREDISPOSITION; EFFECT OF OTHER FOOD CONSTITUENTS; EXCITING
FACTORS

CHAPTER III

THE ANTISCORBUTIC VITAMINE 62

CHARACTERISTICS: RELATION TO HEAT, DRYING, AGING, ULTRA-VIOLET
RAYS, SHAKING 65

MODE OF ACTION--(_a_) DIRECT: AS A NUTRIMENT; ANTITOXIN;
CATALYZER; (_b_) INDIRECT: ENDOCRINE ACTION 69

FATE IN THE BODY: STORING; CONTENT IN BLOOD; EXCRETION; FATE IN
GASTRO-INTESTINAL TRACT; EFFECT ON DIGESTIVE PROCESSES 74

IRREGULARITIES OF ACTION; EFFECT ON GROWTH

CHAPTER IV

PATHOLOGY 81

(_a_) GROSS: GENERAL APPEARANCE; HEMORRHAGES; ANASARCA; HEART;
LUNGS; ALIMENTARY TRACT AND ITS GLANDS; URINARY TRACT; LYMPH
NODES; ORGANS OF INTERNAL SECRETION; BRAIN AND SPINAL CORD;
BONES;

(_b_) MICROSCOPIC: SKIN; MUSCLES; BLOOD-VESSELS;
LUNGS; HEART; INTESTINAL TRACT AND ITS GLANDS; KIDNEY;
ADRENALS; PANCREAS; THYMUS; CENTRAL NERVOUS SYSTEM; PERIPHERAL
NERVES; RETINA; BONES

CHAPTER V

EXPERIMENTAL SCURVY 111

HISTORICAL REVIEW

PATHOGENESIS 116

PATHOLOGY: EFFECT ON THE FOETUS; SCURVY IN THE MONKEY;
MICROSCOPIC PATHOLOGY; BONES; TEETH; NERVES; BLOOD VESSELS;
INTERPRETATION OF BACTERIA IN THE TISSUES 122

SYMPTOMS 135

CHAPTER VI

ANTISCORBUTIC FOODS 143

HISTORICAL REVIEW 143

MILK: RAW; PASTEURIZED; DRIED 150

FRUITS AND FRUIT JUICES: DRIED 153

VEGETABLES: CABBAGE; EFFECT OF HEATING. POTATO. SWEDE 158
DEHYDRATED VEGETABLES: CANNED FOODS (TOMATOES) 166

GERMINATED CEREALS AND PULSES; MEAT AND EGGS; BEER AND ALCOHOLIC
BEVERAGES; MISCELLANEOUS

CONCLUSIONS 173

CHAPTER VII

SYMPTOMATOLOGY AND DIAGNOSIS 176

IN ADULTS 176

IN INFANTS: (_a_) ACUTE; (b) SUBACUTE; (_c_) LATENT.--HEMORRHAGE
OF GUMS; SUBPERIOSTEAL HEMORRHAGE: SKIN; MUCOUS MEMBRANES
AND SUBCUTANEOUS TISSUES; HEMORRHAGES OF INTERNAL ORGANS;
NAILS AND HAIR; ECZEMA; EDEMA; TENDERNESS; BEADING OF RIBS;
SEPARATION OF EPIPHYSIS; "WHITE LINE"; CARDIOVASCULAR SYSTEM;
"CARDIORESPIRATORY SYNDROME"; NERVOUS SYSTEM; URINARY SYSTEM;
THE BLOOD AND BLOOD-VESSELS; NUTRITION AND GROWTH; FEVER;
COMPLICATIONS; EPIDEMIC FORM 183

DIFFERENTIAL DIAGNOSIS: RHEUMATISM; PURPURA; CONGENITAL SYPHILIS;
BONE TUMORS; OSTEOMYELITIS; POLIOMYELITIS, ETC. 219

CHAPTER VIII

PROGNOSIS 225

CHAPTER IX

TREATMENT 230

PREVENTATIVE; CURATIVE

NON-DIETETIC

CHAPTER X

METABOLISM 241

IN ADULTS: BODY EXCHANGES 241

IN INFANTS: BODY EXCHANGES; ANALYSIS OF ORGANS; CHEMISTRY OF
BLOOD 242

IN ANIMALS: MONKEY; GUINEA-PIG 245

CHAPTER XI

RELATION OF SCURVY TO OTHER DISEASES 248

BERIBERI; SHIP-BERIBERI; PELLAGRA; RICKETS; OSTEOGENESIS
IMPERFECTA; OSTEOMALACIA; HUNGER EDEMA; "MEHLNAERSCHADEN";
EXUDATIVE DIATHESIS; DISEASES DUE TO A FOOD EXCESS