Chapter V: Book II: The Beginnings of Modern Science (5)

The names of the different substances that at various times were thought to contain the large quantities of the "essence" during the many centuries of searching for it, form a list of practically all substances that were known, discovered, or invented during the period. Some believed that acids contained the substance; others sought it in minerals or in animal or vegetable products; while still others looked to find it among the distilled "spirits"--the alcoholic liquors and distilled products. On the introduction of alcohol by the Arabs that substance became of all-absorbing interest, and for a long time allured the alchemist into believing that through it they were soon to be rewarded. They rectified and refined it until "sometimes it was so strong that it broke the vessels containing it," but still it failed in its magic power. Later, brandy was substituted for it, and this in turn discarded for more recent discoveries.

There were always, of course, two classes of alchemists: serious investigators whose honesty could not be questioned, and clever impostors whose legerdemain was probably largely responsible for the extended belief in the existence of the philosopher's stone. Sometimes an alchemist practised both, using the profits of his sleight-of-hand to procure the means of carrying on his serious alchemical researches. The impostures of some of these jugglers deceived even the most intelligent and learned men of the time, and so kept the flame of hope constantly burning. The age of cold investigation had not arrived, and it is easy to understand how an unscrupulous mediaeval Hermann or Kellar might completely deceive even the most intelligent and thoughtful scholars. In scoffing at the credulity of such an age, it should not be forgotten that the "Keely motor" was a late nineteenth-century illusion.

But long before the belief in the philosopher's stone had died out, the methods of the legerdemain alchemist had been investigated and reported upon officially by bodies of men appointed to make such investigations, although it took several generations completely to overthrow a superstition that had been handed down through several thousand years. In April of 1772 Monsieur Geoffroy made a report to the Royal Academy of Sciences, at Paris, on the alchemic cheats principally of the sixteenth and seventeenth centuries. In this report he explains many of the seemingly marvellous feats of the unscrupulous alchemists. A very common form of deception was the use of a double-bottomed crucible. A copper or brass crucible was covered on the inside with a layer of wax, cleverly painted so as to resemble the ordinary metal. Between this layer of wax and the bottom of the crucible, however, was a layer of gold dust or silver. When the alchemist wished to demonstrate his power, he had but to place some mercury or whatever substance he chose in the crucible, heat it, throw in a grain or two of some mysterious powder, pronounce a few equally mysterious phrases to impress his audience, and, behold, a lump of precious metal would be found in the bottom of his pot. This was the favorite method of mediocre performers, but was, of course, easily detected.

An equally successful but more difficult way was to insert surreptitiously a lump of metal into the mixture, using an ordinary crucible. This required great dexterity, but was facilitated by the use of many mysterious ceremonies on the part of the operator while performing, just as the modern vaudeville performer diverts the attention of the audience to his right hand while his left is engaged in the trick. Such ceremonies were not questioned, for it was the common belief that the whole process "lay in the spirit as much as in the substance," many, as we have seen, regarding the whole process as a divine manifestation.

Sometimes a hollow rod was used for stirring the mixture in the crucible, this rod containing gold dust, and having the end plugged either with wax or soft metal that was easily melted. Again, pieces of lead were used which had been plugged with lumps of gold carefully covered over; and a very simple and impressive demonstration was making use of a nugget of gold that had been coated over with quicksilver and tarnished so as to resemble lead or some base metal. When this was thrown into acid the coating was removed by chemical action, leaving the shining metal in the bottom of the vessel. In order to perform some of these tricks, it is obvious that the alchemist must have been well supplied with gold, as some of them, when performing before a royal audience, gave the products to their visitors. But it was always a paying investment, for once his reputation was established the gold-maker found an endless variety of ways of turning his alleged knowledge to account, frequently amassing great wealth.

Some of the cleverest of the charlatans often invited royal or other distinguished guests to bring with them iron nails to be turned into gold ones. They were transmuted in the alchemist's crucible before the eyes of the visitors, the juggler adroitly extracting the iron nail and inserting a gold one without detection. It mattered little if the converted gold nail differed in size and shape from the original, for this change in shape could be laid to the process of transmutation; and even the very critical were hardly likely to find fault with the exchange thus made. Furthermore, it was believed that gold possessed the property of changing its bulk under certain conditions, some of the more conservative alchemists maintaining that gold was only increased in bulk, not necessarily created, by certain forms of the magic stone. Thus a very proficient operator was thought to be able to increase a grain of gold into a pound of pure metal, while one less expert could only double, or possibly treble, its original weight.

The actual number of useful discoveries resulting from the efforts of the alchemists is considerable, some of them of incalculable value. Roger Bacon, who lived in the thirteenth century, while devoting much of his time to alchemy, made such valuable discoveries as the theory, at least, of the telescope, and probably gunpowder. Of this latter we cannot be sure that the discovery was his own and that he had not learned of it through the source of old manuscripts. But it is not impossible nor improbable that he may have hit upon the mixture that makes the explosives while searching for the philosopher's stone in his laboratory. "Von Helmont, in the same pursuit, discovered the properties of gas," says Mackay; "Geber made discoveries in chemistry, which were equally important; and Paracelsus, amid his perpetual visions of the transmutation of metals, found that mercury was a remedy for one of the most odious and excruciating of all the diseases that afflict humanity."' As we shall see a little farther on, alchemy finally evolved into modern chemistry, but not until it had passed through several important transitional stages.

ASTROLOGY

In a general way modern astronomy may be considered as the outgrowth of astrology, just as modern chemistry is the result of alchemy. It is quite possible, however, that astronomy is the older of the two; but astrology must have developed very shortly after. The primitive astronomer, having acquired enough knowledge from his observations of the heavenly bodies to make correct predictions, such as the time of the coming of the new moon, would be led, naturally, to believe that certain predictions other than purely astronomical ones could be made by studying the heavens. Even if the astronomer himself did not believe this, some of his superstitious admirers would; for to the unscientific mind predictions of earthly events would surely seem no more miraculous than correct predictions as to the future movements of the sun, moon, and stars. When astronomy had reached a stage of development so that such things as eclipses could be predicted with anything like accuracy, the occult knowledge of the astronomer would be unquestioned. Turning this apparently occult knowledge to account in a mercenary way would then be the inevitable result, although it cannot be doubted that many of the astrologers, in all ages, were sincere in their beliefs.

Later, as the business of astrology became a profitable one, sincere astronomers would find it expedient to practise astrology as a means of gaining a livelihood. Such a philosopher as Kepler freely admitted that he practised astrology "to keep from starving," although he confessed no faith in such predictions. "Ye otherwise philosophers," he said, "ye censure this daughter of astronomy beyond her deserts; know ye not that she must support her mother by her charms."

Once astrology had become an established practice, any considerable knowledge of astronomy was unnecessary, for as it was at best but a system of good guessing as to future events, clever impostors could thrive equally well without troubling to study astronomy. The celebrated astrologers, however, were usually astronomers as well, and undoubtedly based many of their predictions on the position and movements of the heavenly bodies. Thus, the casting of a horoscope that is, the methods by which the astrologers ascertained the relative position of the heavenly bodies at the time of a birth--was a simple but fairly exact procedure. Its basis was the zodiac, or the path traced by the sun in his yearly course through certain constellations. At the moment of the birth of a child, the first care of the astrologer was to note the particular part of the zodiac that appeared on the horizon. The zodiac was then divided into "houses"--that is, into twelve spaces--on a chart. In these houses were inserted the places of the planets, sun, and moon, with reference to the zodiac. When this chart was completed it made a fairly correct diagram of the heavens and the position of the heavenly bodies as they would appear to a person standing at the place of birth at a certain time.

Up to this point the process was a simple one of astronomy. But the next step--the really important one--that of interpreting this chart, was the one which called forth the skill and imagination of the astrologer. In this interpretation, not in his mere observations, lay the secret of his success. Nor did his task cease with simply foretelling future events that were to happen in the life of the newly born infant. He must not only point out the dangers, but show the means whereby they could be averted, and his prophylactic measures, like his predictions, were alleged to be based on his reading of the stars.

But casting a horoscope at the time of births was, of course, only a small part of the astrologer's duty. His offices were sought by persons of all ages for predictions as to their futures, the movements of an enemy, where to find stolen goods, and a host of everyday occurrences. In such cases it is more than probable that the astrologers did very little consulting of the stars in making their predictions. They became expert physiognomists and excellent judges of human nature, and were thus able to foretell futures with the same shrewdness and by the same methods as the modern "mediums," palmists, and fortune-tellers. To strengthen belief in their powers, it became a common thing for some supposedly lost document of the astrologer to be mysteriously discovered after an important event, this document purporting to foretell this very event. It was also a common practice with astrologers to retain, or have access to, their original charts, cleverly altering them from time to time to fit conditions.

The dangers attendant upon astrology were of such a nature that the lot of the astrologer was likely to prove anything but an enviable one. As in the case of the alchemist, the greater the reputation of an astrologer the greater dangers he was likely to fall into. If he became so famous that he was employed by kings or noblemen, his too true or too false prophecies were likely to bring him into disrepute--even to endanger his life.

Throughout the dark age the astrologers flourished, but the sixteenth and seventeenth centuries were the golden age of these impostors. A skilful astrologer was as much an essential to the government as the highest official, and it would have been a bold monarch, indeed, who would undertake any expedition of importance unless sanctioned by the governing stars as interpreted by these officials.

It should not be understood, however, that belief in astrology died with the advent of the Copernican doctrine. It did become separated from astronomy very shortly after, to be sure, and undoubtedly among the scientists it lost much of its prestige. But it cannot be considered as entirely passed away, even to-day, and even if we leave out of consideration street-corner "astrologers" and fortune-tellers, whose signs may be seen in every large city, there still remains quite a large class of relatively intelligent people who believe in what they call "the science of astrology." Needless to say, such people are not found among the scientific thinkers; but it is significant that scarcely a year passes that some book or pamphlet is not published by some ardent believer in astrology, attempting to prove by the illogical dogmas characteristic of unscientific thinkers that astrology is a science. The arguments contained in these pamphlets are very much the same as those of the astrologers three hundred years ago, except that they lack the quaint form of wording which is one of the features that lends interest to the older documents. These pamphlets need not be taken seriously, but they are interesting as exemplifying how difficult it is, even in an age of science, to entirely stamp out firmly established superstitions. Here are some of the arguments advanced in defence of astrology, taken from a little brochure entitled "Astrology Vindicated," published in 1898: "It will be found that a person born when the Sun is in twenty degrees Scorpio has the left ear as his exceptional feature and the nose (Sagittarius) bent towards the left ear. A person born when the Sun is in any of the latter degrees of Taurus, say the twenty-fifth degree, will have a small, sharp, weak chin, curved up towards Gemini, the two vertical lines on the upper lip."(4) The time was when science went out of its way to prove that such statements were untrue; but that time is past, and such writers are usually classed among those energetic but misguided persons who are unable to distinguish between logic and sophistry.

In England, from the time of Elizabeth to the reign of William and Mary, judicial astrology was at its height. After the great London fire, in 1666, a committee of the House of Commons publicly summoned the famous astrologer, Lilly, to come before Parliament and report to them on his alleged prediction of the calamity that had befallen the city. Lilly, for some reason best known to himself, denied having made such a prediction, being, as he explained, "more interested in determining affairs of much more importance to the future welfare of the country." Some of the explanations of his interpretations will suffice to show their absurdities, which, however, were by no means regarded as absurdities at that time, for Lilly was one of the greatest astrologers of his day. He said that in 1588 a prophecy had been printed in Greek characters which foretold exactly the troubles of England between the years 1641. and 1660. "And after him shall come a dreadful dead man," ran the prophecy, "and with him a royal G of the best blood in the world, and he shall have the crown and shall set England on the right way and put out all heresies." His interpretation of this was that, "Monkery being extinguished above eighty or ninety years, and the Lord General's name being Monk, is the dead man. The royal G or C (it is gamma in the Greek, intending C in the Latin, being the third letter in the alphabet) is Charles II., who, for his extraction, may be said to be of the best blood of the world."(5)

This may be taken as a fair sample of Lilly's interpretations of astrological prophesies, but many of his own writings, while somewhat more definite and direct, are still left sufficiently vague to allow his skilful interpretations to set right an apparent mistake. One of his famous documents was "The Starry Messenger," a little pamphlet purporting to explain the phenomenon of a "strange apparition of three suns" that were seen in London on November 19, 1644---the anniversary of the birth of Charles I., then the reigning monarch. This phenomenon caused a great stir among the English astrologers, coming, as it did, at a time of great political disturbance. Prophecies were numerous, and Lilly's brochure is only one of many that appeared at that time, most of which, however, have been lost. Lilly, in his preface, says: "If there be any of so prevaricate a judgment as to think that the apparition of these three Suns doth intimate no Novelle thing to happen in our own Climate, where they were manifestly visible, I shall lament their indisposition, and conceive their brains to be shallow, and voyde of understanding humanity, or notice of common History."

Having thus forgiven his few doubting readers, who were by no means in the majority in his day, he takes up in review the records of the various appearances of three suns as they have occurred during the Christian era, showing how such phenomena have governed certain human events in a very definite manner. Some of these are worth recording.

"Anno 66. A comet was seen, and also three Suns: In which yeer, Florus President of the Jews was by them slain. Paul writes to Timothy. The Christians are warned by a divine Oracle, and depart out of Jerusalem. Boadice a British Queen, killeth seventy thousand Romans. The Nazareni, a scurvie Sect, begun, that boasted much of Revelations and Visions. About a year after Nero was proclaimed enemy to the State of Rome."

Again, "Anno 1157, in September, there were seen three Suns together, in as clear weather as could be: And a few days after, in the same month, three Moons, and, in the Moon that stood in the middle, a white Crosse. Sueno, King of Denmark, at a great Feast, killeth Canutus: Sueno is himself slain, in pursuit of Waldemar. The Order of Eremites, according to the rule of Saint Augustine, begun this year; and in the next, the Pope submits to the Emperour: (was not this miraculous?) Lombardy was also adjudged to the Emperour."

Continuing this list of peculiar phenomena he comes down to within a few years of his own time.

"Anno 1622, three Suns appeared at Heidelberg. The woful Calamities that have ever since fallen upon the Palatinate, we are all sensible of, and of the loss of it, for any thing I see, for ever, from the right Heir. Osman the great Turk is strangled that year; and Spinola besiegeth Bergen up Zoom, etc."

Fortified by the enumeration of these past events, he then proceeds to make his deductions. "Only this I must tell thee," he writes, "that the interpretation I write is, I conceive, grounded upon probable foundations; and who lives to see a few years over his head, will easily perceive I have unfolded as much as was fit to discover, and that my judgment was not a mile and a half from truth."

There is a great significance in this "as much as was fit to discover"--a mysterious something that Lilly thinks it expedient not to divulge. But, nevertheless, one would imagine that he was about to make some definite prediction about Charles I., since these three suns appeared upon his birthday and surely must portend something concerning him. But after rambling on through many pages of dissertations upon planets and prophecies, he finally makes his own indefinite prediction.

"O all you Emperors, Kings, Princes, Rulers and Magistrates of Europe, this unaccustomed Apparition is like the Handwriting in Daniel to some of you; it premonisheth you, above all other people, to make your peace with God in time. You shall every one of you smart, and every one of you taste (none excepted) the heavie hand of God, who will strengthen your subjects with invincible courage to suppress your misgovernments and Oppressions in Church or Common-wealth;... Those words are general: a word for my own country of England.... Look to yourselves; here's some monstrous death towards you. But to whom? wilt thou say. Herein we consider the Signe, Lord thereof, and the House; The Sun signifies in that Royal Signe, great ones; the House signifies captivity, poison, Treachery: From which is derived thus much, That some very great man, what King, Prince, Duke, or the like, I really affirm I perfectly know not, shall, I say, come to some such untimely end."(6)

Here is shown a typical example of astrological prophecy, which seems to tell something or nothing, according to the point of view of the reader. According to a believer in astrology, after the execution of Charles I., five years later, this could be made to seem a direct and exact prophecy. For example, he says: "You Kings, Princes, etc.,... it premonisheth you... to make your peace with God.... Look to yourselves; here's some monstrous death towards you.... That some very great man, what King, Prince,. shall, I say, come to such untimely end."

But by the doubter the complete prophecy could be shown to be absolutely indefinite, and applicable as much to the king of France or Spain as to Charles I., or to any king in the future, since no definite time is stated. Furthermore, Lilly distinctly states, "What King, Prince, Duke, or the like, I really affirm I perfectly know not"--which last, at least, was a most truthful statement. The same ingenuity that made "Gen. Monk" the "dreadful dead man," could easily make such a prediction apply to the execution of Charles I. Such a definite statement that, on such and such a day a certain number of years in the future, the monarch of England would be beheaded--such an exact statement can scarcely be found in any of the works on astrology. It should be borne in mind, also, that Lilly was of the Cromwell party and opposed to the king.

After the death of Charles I., Lilly admitted that the monarch had given him a thousand pounds to cast his horoscope. "I advised him," says Lilly, "to proceed eastwards; he went west, and all the world knows the result." It is an unfortunate thing for the cause of astrology that Lilly failed to mention this until after the downfall of the monarch. In fact, the sudden death, or decline in power, of any monarch, even to-day, brings out the perennial post-mortem predictions of astrologers.

We see how Lilly, an opponent of the king, made his so-called prophecy of the disaster of the king and his army. At the same time another celebrated astrologer and rival of Lilly, George Wharton, also made some predictions about the outcome of the eventful march from Oxford. Wharton, unlike Lilly, was a follower of the king's party, but that, of course, should have had no influence in his "scientific" reading of the stars. Wharton's predictions are much less verbose than Lilly's, much more explicit, and, incidentally, much more incorrect in this particular instance. "The Moon Lady of the 12," he wrote, "and moving betwixt the 8 degree, 34 min., and 21 degree, 26 min. of Aquarius, gives us to understand that His Majesty shall receive much contentment by certain Messages brought him from foreign parts; and that he shall receive some sudden and unexpected supply of... by the means of some that assimilate the condition of his Enemies: And withal this comfort; that His Majesty shall be exceeding successful in Besieging Towns, Castles, or Forts, and in persuing the enemy.

"Mars his Sextile to the Sun, Lord of the Ascendant (which happeneth the 18 day of May) will encourage our Soldiers to advance with much alacrity and cheerfulness of spirit; to show themselves gallant in the most dangerous attempt.... And now to sum up all: It is most apparent to every impartial and ingenuous judgment; That although His Majesty cannot expect to be secured from every trivial disaster that may befall his army, either by the too much Presumption, Ignorance, or Negligence of some particular Persons (which is frequently incident and unavoidable in the best of Armies), yet the several positions of the Heavens duly considered and compared among themselves, as well in the prefixed Scheme as at the Quarterly Ingresses, do generally render His Majesty and his whole Army unexpectedly victorious and successful in all his designs; Believe it (London), thy Miseries approach, they are like to be many, great, and grievous, and not to be diverted, unless thou seasonably crave Pardon of God for being Nurse to this present Rebellion, and speedily submit to thy Prince's Mercy; Which shall be the daily Prayer of Geo. Wharton."(7)

In the light of after events, it is probable that Wharton's stock as an astrologer was not greatly enhanced by this document, at least among members of the Royal family. Lilly's book, on the other hand, became a favorite with the Parliamentary army.

After the downfall and death of Napoleon there were unearthed many alleged authentic astrological documents foretelling his ruin. And on the death of George IV., in 1830, there appeared a document (unknown, as usual, until that time) purporting to foretell the death of the monarch to the day, and this without the astrologer knowing that his horoscope was being cast for a monarch. A full account of this prophecy is told, with full belief, by Roback, a nineteenth-century astrologer. He says:

"In the year 1828, a stranger of noble mien, advanced in life, but possessing the most bland manners, arrived at the abode of a celebrated astrologer in London," asking that the learned man foretell his future. "The astrologer complied with the request of the mysterious visitor, drew forth his tables, consulted his ephemeris, and cast the horoscope or celestial map for the hour and the moment of the inquiry, according to the established rules of his art.

"The elements of his calculation were adverse, and a feeling of gloom cast a shade of serious thought, if not dejection, over his countenance.

"'You are of high rank,' said the astrologer, as he calculated and looked on the stranger, 'and of illustrious title.' The stranger made a graceful inclination of the head in token of acknowledgment of the complimentary remarks, and the astrologer proceeded with his mission.

"The celestial signs were ominous of calamity to the stranger, who, probably observing a sudden change in the countenance of the astrologer, eagerly inquired what evil or good fortune had been assigned him by the celestial orbs.

"'To the first part of your inquiry,' said the astrologer, 'I can readily reply. You have been a favorite of fortune; her smiles on you have been abundant, her frowns but few; you have had, perhaps now possess, wealth and power; the impossibility of their accomplishment is the only limit to the fulfilment of your desires.'"

"'You have spoken truly of the past,' said the stranger. 'I have full faith in your revelations of the future: what say you of my pilgrimage in this life--is it short or long?'

"'I regret,' replied the astrologer, in answer to this inquiry, 'to be the herald of ill, though TRUE, fortune; your sojourn on earth will be short.'

"'How short?' eagerly inquired the excited and anxious stranger.

"'Give me a momentary truce,' said the astrologer; 'I will consult the horoscope, and may possibly find some mitigating circumstances.'

"Having cast his eyes over the celestial map, and paused for some moments, he surveyed the countenance of the stranger with great sympathy, and said, 'I am sorry that I can find no planetary influences that oppose your destiny--your death will take place in two years.'

"The event justified the astrologic prediction: George IV. died on May 18, 1830, exactly two years from the day on which he had visited the astrologer."(8)

This makes a very pretty story, but it hardly seems like occult insight that an astrologer should have been able to predict an early death of a man nearly seventy years old, or to have guessed that his well-groomed visitor "had, perhaps now possesses, wealth and power." Here again, however, the point of view of each individual plays the governing part in determining the importance of such a document. To the scientist it proves nothing; to the believer in astrology, everything. The significant thing is that it appeared shortly AFTER the death of the monarch.

On the Continent astrologers were even more in favor than in England. Charlemagne, and some of his immediate successors, to be sure, attempted to exterminate them, but such rulers as Louis XI. and Catherine de' Medici patronized and encouraged them, and it was many years after the time of Copernicus before their influence was entirely stamped out even in official life. There can be no question that what gave the color of truth to many of the predictions was the fact that so many of the prophecies of sudden deaths and great conflagrations were known to have come true--in many instances were made to come true by the astrologer himself. And so it happened that when the prediction of a great conflagration at a certain time culminated in such a conflagration, many times a second but less-important burning took place, in which the ambitious astrologer, or his followers, took a central part about a stake, being convicted of incendiarism, which they had committed in order that their prophecies might be fulfilled.

But, on the other hand, these predictions were sometimes turned to account by interested friends to warn certain persons of approaching dangers.

For example, a certain astrologer foretold the death of Prince Alexander de' Medici. He not only foretold the death, but described so minutely the circumstances that would attend it, and gave such a correct description of the assassin who should murder the prince, that he was at once suspected of having a hand in the assassination. It developed later, however, that such was probably not the case; but that some friend of Prince Alexander, knowing of the plot to take his life, had induced the astrologer to foretell the event in order that the prince might have timely warning and so elude the conspirators.

The cause of the decline of astrology was the growing prevalence of the new spirit of experimental science. Doubtless the most direct blow was dealt by the Copernican theory. So soon as this was established, the recognition of the earth's subordinate place in the universe must have made it difficult for astronomers to be longer deceived by such coincidences as had sufficed to convince the observers of a more credulous generation. Tycho Brahe was, perhaps, the last astronomer of prominence who was a conscientious practiser of the art of the astrologer.

VII. FROM PARACELSUS TO HARVEY

PARACELSUS

In the year 1526 there appeared a new lecturer on the platform at the University at Basel--a small, beardless, effeminate-looking person--who had already inflamed all Christendom with his peculiar philosophy, his revolutionary methods of treating diseases, and his unparalleled success in curing them. A man who was to be remembered in after-time by some as the father of modern chemistry and the founder of modern medicine; by others as madman, charlatan, impostor; and by still others as a combination of all these. This soft-cheeked, effeminate, woman-hating man, whose very sex has been questioned, was Theophrastus von Hohenheim, better known as Paracelsus (1493-1541).

To appreciate his work, something must be known of the life of the man. He was born near Maria-Einsiedeln, in Switzerland, the son of a poor physician of the place. He began the study of medicine under the instruction of his father, and later on came under the instruction of several learned churchmen. At the age of sixteen he entered the University of Basel, but, soon becoming disgusted with the philosophical teachings of the time, he quitted the scholarly world of dogmas and theories and went to live among the miners in the Tyrol, in order that he might study nature and men at first hand. Ordinary methods of study were thrown aside, and he devoted his time to personal observation--the only true means of gaining useful knowledge, as he preached and practised ever after. Here he became familiar with the art of mining, learned the physical properties of minerals, ores, and metals, and acquired some knowledge of mineral waters. More important still, he came in contact with such diseases, wounds, and injuries as miners are subject to, and he tried his hand at the practical treatment of these conditions, untrammelled by the traditions of a profession in which his training had been so scant.

Having acquired some empirical skill in treating diseases, Paracelsus set out wandering from place to place all over Europe, gathering practical information as he went, and learning more and more of the medicinal virtues of plants and minerals. His wanderings covered a period of about ten years, at the end of which time he returned to Basel, where he was soon invited to give a course of lectures in the university.

These lectures were revolutionary in two respects--they were given in German instead of time-honored Latin, and they were based upon personal experience rather than upon the works of such writers as Galen and Avicenna. Indeed, the iconoclastic teacher spoke with open disparagement of these revered masters, and openly upbraided his fellow-practitioners for following their tenets. Naturally such teaching raised a storm of opposition among the older physicians, but for a time the unparalleled success of Paracelsus in curing diseases more than offset his unpopularity. Gradually, however, his bitter tongue and his coarse personality rendered him so unpopular, even among his patients, that, finally, his liberty and life being jeopardized, he was obliged to flee from Basel, and became a wanderer. He lived for brief periods in Colmar, Nuremberg, Appenzell, Zurich, Pfeffers, Augsburg, and several other cities, until finally at Salzburg his eventful life came to a close in 1541. His enemies said that he had died in a tavern from the effects of a protracted debauch; his supporters maintained that he had been murdered at the instigation of rival physicians and apothecaries.

But the effects of his teachings had taken firm root, and continued to spread after his death. He had shown the fallibility of many of the teachings of the hitherto standard methods of treating diseases, and had demonstrated the advantages of independent reasoning based on observation. In his Magicum he gives his reasons for breaking with tradition. "I did," he says, "embrace at the beginning these doctrines, as my adversaries (followers of Galen) have done, but since I saw that from their procedures nothing resulted but death, murder, stranglings, anchylosed limbs, paralysis, and so forth, that they held most diseases incurable.... therefore have I quitted this wretched art, and sought for truth in any other direction. I asked myself if there were no such thing as a teacher in medicine, where could I learn this art best? Nowhere better than the open book of nature, written with God's own finger." We shall see, however, that this "book of nature" taught Paracelsus some very strange lessons. Modesty was not one of these. "Now at this time," he declares, "I, Theophrastus Paracelsus, Bombast, Monarch of the Arcana, was endowed by God with special gifts for this end, that every searcher after this supreme philosopher's work may be forced to imitate and to follow me, be he Italian, Pole, Gaul, German, or whatsoever or whosoever he be. Come hither after me, all ye philosophers, astronomers, and spagirists.... I will show and open to you... this corporeal regeneration."(1)

Paracelsus based his medical teachings on four "pillars"--philosophy, astronomy, alchemy, and virtue of the physician--a strange-enough equipment surely, and yet, properly interpreted, not quite so anomalous as it seems at first blush. Philosophy was the "gate of medicine," whereby the physician entered rightly upon the true course of learning; astronomy, the study of the stars, was all-important because "they (the stars) caused disease by their exhalations, as, for instance, the sun by excessive heat"; alchemy, as he interpreted it, meant the improvement of natural substances for man's benefit; while virtue in the physician was necessary since "only the virtuous are permitted to penetrate into the innermost nature of man and the universe."

All his writings aim to promote progress in medicine, and to hold before the physician a grand ideal of his profession. In this his views are wide and far-reaching, based on the relationship which man bears to nature as a whole; but in his sweeping condemnations he not only rejected Galenic therapeutics and Galenic anatomy, but condemned dissections of any kind. He laid the cause of all diseases at the door of the three mystic elements--salt, sulphur, and mercury. In health he supposed these to be mingled in the body so as to be indistinguishable; a slight separation of them produced disease; and death he supposed to be the result of their complete separation. The spiritual agencies of diseases, he said, had nothing to do with either angels or devils, but were the spirits of human beings.

He believed that all food contained poisons, and that the function of digestion was to separate the poisonous from the nutritious. In the stomach was an archaeus, or alchemist, whose duty was to make this separation. In digestive disorders the archaeus failed to do this, and the poisons thus gaining access to the system were "coagulated" and deposited in the joints and various other parts of the body. Thus the deposits in the kidneys and tartar on the teeth were formed; and the stony deposits of gout were particularly familiar examples of this. All this is visionary enough, yet it shows at least a groping after rational explanations of vital phenomena.

Like most others of his time, Paracelsus believed firmly in the doctrine of "signatures"--a belief that every organ and part of the body had a corresponding form in nature, whose function was to heal diseases of the organ it resembled. The vagaries of this peculiar doctrine are too numerous and complicated for lengthy discussion, and varied greatly from generation to generation. In general, however, the theory may be summed up in the words of Paracelsus: "As a woman is known by her shape, so are the medicines." Hence the physicians were constantly searching for some object of corresponding shape to an organ of the body. The most natural application of this doctrine would be the use of the organs of the lower animals for the treatment of the corresponding diseased organs in man. Thus diseases of the heart were to be treated with the hearts of animals, liver disorders with livers, and so on. But this apparently simple form of treatment had endless modifications and restrictions, for not all animals were useful. For example, it was useless to give the stomach of an ox in gastric diseases when the indication in such cases was really for the stomach of a rat. Nor were the organs of animals the only "signatures" in nature. Plants also played a very important role, and the herb-doctors devoted endless labor to searching for such plants. Thus the blood-root, with its red juice, was supposed to be useful in blood diseases, in stopping hemorrhage, or in subduing the redness of an inflammation.

Paracelsus's system of signatures, however, was so complicated by his theories of astronomy and alchemy that it is practically beyond comprehension. It is possible that he himself may have understood it, but it is improbable that any one else did--as shown by the endless discussions that have taken place about it. But with all the vagaries of his theories he was still rational in his applications, and he attacked to good purpose the complicated "shot-gun" prescriptions of his contemporaries, advocating more simple methods of treatment.

The ever-fascinating subject of electricity, or, more specifically, "magnetism," found great favor with him, and with properly adjusted magnets he claimed to be able to cure many diseases. In epilepsy and lockjaw, for example, one had but to fasten magnets to the four extremities of the body, and then, "when the proper medicines were given," the cure would be effected. The easy loop-hole for excusing failure on the ground of improper medicines is obvious, but Paracelsus declares that this one prescription is of more value than "all the humoralists have ever written or taught."

Since Paracelsus condemned the study of anatomy as useless, he quite naturally regarded surgery in the same light. In this he would have done far better to have studied some of his predecessors, such as Galen, Paul of Aegina, and Avicenna. But instead of "cutting men to pieces," he taught that surgeons would gain more by devoting their time to searching for the universal panacea which would cure all diseases, surgical as well as medical. In this we detect a taint of the popular belief in the philosopher's stone and the magic elixir of life, his belief in which have been stoutly denied by some of his followers. He did admit, however, that one operation alone was perhaps permissible--lithotomy, or the "cutting for stone."

His influence upon medicine rests undoubtedly upon his revolutionary attitude, rather than on any great or new discoveries made by him. It is claimed by many that he brought prominently into use opium and mercury, and if this were indisputably proven his services to medicine could hardly be overestimated. Unfortunately, however, there are good grounds for doubting that he was particularly influential in reintroducing these medicines. His chief influence may perhaps be summed up in a single phrase--he overthrew old traditions.

To Paracelsus's endeavors, however, if not to the actual products of his work, is due the credit of setting in motion the chain of thought that developed finally into scientific chemistry. Nor can the ultimate aim of the modern chemist seek a higher object than that of this sixteenth-century alchemist, who taught that "true alchemy has but one aim and object, to extract the quintessence of things, and to prepare arcana, tinctures, and elixirs which may restore to man the health and soundness he has lost."

THE GREAT ANATOMISTS

About the beginning of the sixteenth century, while Paracelsus was scoffing at the study of anatomy as useless, and using his influence against it, there had already come upon the scene the first of the great anatomists whose work was to make the century conspicuous in that branch of medicine.

The young anatomist Charles etienne (1503-1564) made one of the first noteworthy discoveries, pointing out for the first time that the spinal cord contains a canal, continuous throughout its length. He also made other minor discoveries of some importance, but his researches were completely overshadowed and obscured by the work of a young Fleming who came upon the scene a few years later, and who shone with such brilliancy in the medical world that he obscured completely the work of his contemporary until many years later. This young physician, who was destined to lead such an eventful career and meet such an untimely end as a martyr to science, was Andrew Vesalius (1514-1564), who is called the "greatest of anatomists." At the time he came into the field medicine was struggling against the dominating Galenic teachings and the theories of Paracelsus, but perhaps most of all against the superstitions of the time. In France human dissections were attended with such dangers that the young Vesalius transferred his field of labors to Italy, where such investigations were covertly permitted, if not openly countenanced.

From the very start the young Fleming looked askance at the accepted teachings of the day, and began a series of independent investigations based upon his own observations. The results of these investigations he gave in a treatise on the subject which is regarded as the first comprehensive and systematic work on human anatomy. This remarkable work was published in the author's twenty-eighth or twenty-ninth year. Soon after this Vesalius was invited as imperial physician to the court of Emperor Charles V. He continued to act in the same capacity at the court of Philip II., after the abdication of his patron. But in spite of this royal favor there was at work a factor more powerful than the influence of the monarch himself--an instrument that did so much to retard scientific progress, and by which so many lives were brought to a premature close.

Vesalius had received permission from the kinsmen of a certain grandee to perform an autopsy. While making his observations the heart of the outraged body was seen to palpitate--so at least it was reported. This was brought immediately to the attention of the Inquisition, and it was only by the intervention of the king himself that the anatomist escaped the usual fate of those accused by that tribunal. As it was, he was obliged to perform a pilgrimage to the Holy Land. While returning from this he was shipwrecked, and perished from hunger and exposure on the island of Zante.

At the very time when the anatomical writings of Vesalius were startling the medical world, there was living and working contemporaneously another great anatomist, Eustachius (died 1574), whose records of his anatomical investigations were ready for publication only nine years after the publication of the work of Vesalius. Owing to the unfortunate circumstances of the anatomist, however, they were never published during his lifetime--not, in fact, until 1714. When at last they were given to the world as Anatomical Engravings, they showed conclusively that Eustachius was equal, if not superior to Vesalius in his knowledge of anatomy. It has been said of this remarkable collection of engravings that if they had been published when they were made in the sixteenth century, anatomy would have been advanced by at least two centuries. But be this as it may, they certainly show that their author was a most careful dissector and observer.

Eustachius described accurately for the first time certain structures of the middle ear, and rediscovered the tube leading from the ear to the throat that bears his name. He also made careful studies of the teeth and the phenomena of first and second dentition. He was not baffled by the minuteness of structures and where he was unable to study them with the naked eye he used glasses for the purpose, and resorted to macerations and injections for the study of certain complicated structures. But while the fruit of his pen and pencil were lost for more than a century after his death, the effects of his teachings were not; and his two pupils, Fallopius and Columbus, are almost as well known to-day as their illustrious teacher. Columbus (1490-1559) did much in correcting the mistakes made in the anatomy of the bones as described by Vesalius. He also added much to the science by giving correct accounts of the shape and cavities of the heart, and made many other discoveries of minor importance. Fallopius (1523-1562) added considerably to the general knowledge of anatomy, made several discoveries in the anatomy of the ear, and also several organs in the abdominal cavity.

At this time a most vitally important controversy was in progress as to whether or not the veins of the bodies were supplied with valves, many anatomists being unable to find them. Etienne had first described these structures, and Vesalius had confirmed his observations. It would seem as if there could be no difficulty in settling the question as to the fact of such valves being present in the vessels, for the demonstration is so simple that it is now made daily by medical students in all physiological laboratories and dissecting-rooms. But many of the great anatomists of the sixteenth century were unable to make this demonstration, even when it had been brought to their attention by such an authority as Vesalius. Fallopius, writing to Vesalius on the subject in 1562, declared that he was unable to find such valves. Others, however, such as Eustachius and Fabricius (1537-1619), were more successful, and found and described these structures. But the purpose served by these valves was entirely misinterpreted. That they act in preventing the backward flow of the blood in the veins on its way to the heart, just as the valves of the heart itself prevent regurgitation, has been known since the time of Harvey; but the best interpretation that could be given at that time, even by such a man as Fabricius, was that they acted in retarding the flow of the blood as it comes from the heart, and thus prevent its too rapid distribution throughout the body. The fact that the blood might have been going towards the heart, instead of coming from it, seems never to have been considered seriously until demonstrated so conclusively by Harvey.

Of this important and remarkable controversy over the valves in veins, Withington has this to say: "This is truly a marvellous story. A great Galenic anatomist is first to give a full and correct description of the valves and their function, but fails to see that any modification of the old view as to the motion of the blood is required. Two able dissectors carefully test their action by experiment, and come to a result, the exact reverse of the truth. Urged by them, the two foremost anatomists of the age make a special search for valves and fail to find them. Finally, passing over lesser peculiarities, an aged and honorable professor, who has lived through all this, calmly asserts that no anatomist, ancient or modern, has ever mentioned valves in veins till he discovered them in 1574!"(2)

Among the anatomists who probably discovered these valves was Michael Servetus (1511-1553); but if this is somewhat in doubt, it is certain that he discovered and described the pulmonary circulation, and had a very clear idea of the process of respiration as carried on in the lungs. The description was contained in a famous document sent to Calvin in 1545--a document which the reformer carefully kept for seven years in order that he might make use of some of the heretical statements it contained to accomplish his desire of bringing its writer to the stake. The awful fate of Servetus, the interesting character of the man, and the fact that he came so near to anticipating the discoveries of Harvey make him one of the most interesting figures in medical history.

In this document which was sent to Calvin, Servetus rejected the doctrine of natural, vital, and animal spirits, as contained in the veins, arteries, and nerves respectively, and made the all-important statement that the fluids contained in veins and arteries are the same. He showed also that the blood is "purged from fume" and purified by respiration in the lungs, and declared that there is a new vessel in the lungs, "formed out of vein and artery." Even at the present day there is little to add to or change in this description of Servetus's.

By keeping this document, pregnant with advanced scientific views, from the world, and in the end only using it as a means of destroying its author, the great reformer showed the same jealousy in retarding scientific progress as had his arch-enemies of the Inquisition, at whose dictates Vesalius became a martyr to science, and in whose dungeons etienne perished.

THE COMING OF HARVEY

The time was ripe for the culminating discovery of the circulation of the blood; but as yet no one had determined the all-important fact that there are two currents of blood in the body, one going to the heart, one coming from it. The valves in the veins would seem to show conclusively that the venous current did not come from the heart, and surgeons must have observed thousands of times the every-day phenomenon of congested veins at the distal extremity of a limb around which a ligature or constriction of any kind had been placed, and the simultaneous depletion of the vessels at the proximal points above the ligature. But it should be remembered that inductive science was in its infancy. This was the sixteenth, not the nineteenth century, and few men had learned to put implicit confidence in their observations and convictions when opposed to existing doctrines. The time was at hand, however, when such a man was to make his appearance, and, as in the case of so many revolutionary doctrines in science, this man was an Englishman. It remained for William Harvey (1578-1657) to solve the great mystery which had puzzled the medical world since the beginning of history; not only to solve it, but to prove his case so conclusively and so simply that for all time his little booklet must he handed down as one of the great masterpieces of lucid and almost faultless demonstration.