Chapter LXV: Part II: , Showing Predominance of Malarial Element . . . . 617 (64)

Complications of cholera, 735
of erysipelas, 633
of idiopathic parotitis, 623
of influenza, 868
of pertussis, 843
of plague, 780
of relapsing fever, 396-410
of rötheln, 587
of rubeola, 570
causes, 570
of scarlet fever, 510
of typhoid fever, 292
treatment, 335
of vaccination, 468
of vaccinia, 464
of varicella, 483
of variola, 445

Confluent small-pox, 440

Conjunctiva, condition of, in human glanders, 921
symptoms of diphtheria of, 670

Conjunctival diphtheria, local treatment, 712

Conjunctivitis, diphtheritic, symptoms, 670

Consanguineous marriages, effects, 131

Constipation in cerebro-spinal meningitis, 814
in grave form of the plague, 779
in rubeola, treatment, 581
in typhoid fever, treatment, 333
in typhus fever, treatment, 367
significance of, in general diagnosis, 163

Constitutional infection, absence of, in vaccinia, 460
of syphilis, hereditary nature, 127
taints, conveyance of, by vaccination, 471
treatment of anthrax, 944
of pyæmia, 982

Contagion as a cause of disease, 135, 200
definition of, 200
of dengue, 884
of erysipelas, manner of propagation, 630
nature, 630
of influenza, 862
of relapsing fever, transmission, 373
of rabies and hydrophobia, 891
dissemination, 891
of rötheln, nature, 583
of rubeola, modes of dissemination, 558
mode of entering the body, 558
nature, 557
in typhus fever, nature, 343
modes of transmission, 344

Contagium of variola, duration of activity, 435
mode of entering body, 435
nature, 435
period of greatest activity, 435

Contagious diseases, characteristics, 137

Contagious nature of cholera, objections to, 729

Contagiousness of anthrax, 928
of cerebro-spinal meningitis, 803
of cholera, 721
of dengue, 884
of diphtheria, 678
of erysipelas, 630
of glanders, 911
of influenza, 862, 863
of leprosy, 788
of the plague, 776
of puerperal fever, 1017
of pyæmia, 960
of rabies and hydrophobia, 891
of scarlet fever, 494
of typhoid fever, 248
of typhus fever, 343
period of greatest, 345
of varicella, 481
of variola, 435

Convalescence, choice of diet, 206
in cerebro-spinal meningitis, 819
management, 835
in cholera, 735
management, 764
in chronic glanders in man, 922
in dengue, 882
in grave form of the plague, 779
in erysipelas, management, 639
in influenza, treatment, 875
in relapsing fever, 393
in scarlet fever, management, 544
in typhoid fever, management, 335
in typhus fever, management, 368

Convulsions during hot stage of intermittent fever, treatment, 597
in cerebro-spinal meningitis, 810
in relapsing fever, 384
complicating rubeola, 572
in prodromal stage of rubeola, 565
in rubeola, treatment, 581
in yellow fever, treatment, 653

Cooking, necessity of a physician's knowledge of, 196

Corpuscles, pus-, 43

Corrosive sublimate, use of, as antiseptic in puerperal fever, 1025,
1029

Coryza, chronic, following rubeola, 574
complicating scarlet fever, 520
of scarlet fever, treatment, 546

Cough, in rubeola, treatment, 581
significance of, in general diagnosis, 158

Counterirritants, use of, in pertussis, 848

Course of vaccinia, 458
irregularities, 460

Cow-pox, 456
spontaneous, 456

Cramps in beriberi, 1039
in cholera, 740
treatment, 769
causes, 740

Cretinism and goitre, hereditary nature, 128

Croup, respiration, 157

Croupous inflammation distinguished from croup, 49
of fauces, complicating scarlet fever, 516
membrane, 685
characters, 685
mode of formation, 685
metamorphosis, 80

Crust in vaccinia, composition, 464

Crusts, objections to use of, in vaccination, 476

Cubebs, use of, in diphtheria, 709

Cultivation of bacillus tuberculosis, 100

Curare, use of, in treatment of hydrophobia, 907

Cutaneous deposits in glanders, microscopic characters, 917
diphtheria, treatment, 713
lesions of glanders in man, 922
symptoms of glanders in man, 921

Cysts, definition, 115, 121

D.

Deaf-mutism following cerebro-spinal meningitis, 819

Deafness in cerebro-spinal meningitis, 811

Death, causes of, in cerebro-spinal meningitis, 818
in glanders, 915

Debility in cerebro-spinal meningitis, 813
in influenza, treatment, 876
influence of, in causation of glanders, 912
in relapsing fever, 386

Decline, stage of, in pertussis, 841

Decubitus, significance of, in general diagnosis, 150

Definition of anthrax, 926
of beriberi, 1038
of cerebro-spinal meningitis, 795
of cholera, 715
of contagion, 200
of cysts, 115, 121
of dengue, 880
of diphtheria, 656
of erysipelas, 629
of glanders, 909
of idiopathic parotitis, 620
of influenza, 851
of leprosy, 785
of pernicious malarial fever, 605
of pertussis, 836
of the plague, 771
of puerperal fever, 984
of pyæmia, 953
of rabies and hydrophobia, 886
of relapsing fever, 369
of remittent fever, 598
of rötheln, 582
of rubeola, 557
of septicæmia, 953
of simple continued fever, 231
of symptomatic parotitis, 625
of term "climate," 185
of typhoid fever, 237
of typho-malarial fever, 614
of vaccinia, 455
of varicella, 481
of variola, 434
of yellow fever, 640

Degeneration, 72
amyloid, 84
cheesy, 79
colloid, 83
fibrinous, 80
fatty, 74
granular, 72
hyaline, 80
lardaceous, 84
mucous, 82
of tubercle, 96
parenchymatous, 73
waxy, 84

Deglutition, difficult, in idiopathic parotitis, treatment, 624

Delirium in cerebro-spinal meningitis, 812
in erysipelas, treatment, 637
in idiopathic parotitis, treatment, 624
in pyæmia, 971
in relapsing fever, 384
in typhoid fever, 278
treatment, 334
in typhus fever, 348
treatment, 366
in yellow fever, treatment, 653
significance of, in general diagnosis, 166

Demonstration of bacillus of glanders, 914

DENGUE, 879
Synonyms, 879
History, 879
Definition, 880
Etiology, 883
Specific origin, 884
Contagiousness, 884
Symptoms--prodromal stage, 880
Mode of onset, 880
Temperature, 881
Pulse, 881
Delirium, 881
Facies, 881
State of gastro-intestinal tract, 881
State of tongue, 881
Stomach and bowels, 881
State of urine, 881
Eruptions, 881
Hemorrhages, 882
Prostration, 882
Convalescence, 882
Duration of, 882
Morbid anatomy, 882
Specific nature of, 882
Relation to acute articular rheumatism, 883
Changes in abdominal organs, 883
Diagnosis, 884
From acute articular rheumatism, 884
From yellow fever, 884
Prognosis, 885
Treatment, 885
Use of colchicum, 885
quinia, 885
opium, 885

Depletion, local, use of, in cerebro-spinal meningitis, 830

Depressing emotions, as a cause of typhoid fever, 245

Dermatitis, complicating vaccination, 468
vaccination, treatment, 469

Desquamation, date of, in mild scarlet fever, 506
in erysipelas, 633
in relapsing fever, 377

Desiccation in varicella, 482
in variola, 440

Diagnosis, general, 148
divisions of, 148
main direction of inquiries, 148
proper method of procedure, 150
significance of alteration of voice in, 158
of anthrax in animals, 936
in man, 942
of cerebro-spinal meningitis, 826
of cholera, 750
of comatose form of pernicious malarial fever, 609
of dengue, 884
of diphtheria, 689
of erysipelas, 635
of idiopathic parotitis, 624
of glanders in horse, 918
of glanders in man, 923
of influenza, 872
of intermittent fever, 594
of leprosy, 792
of the plague, 782
of pyæmia from septicæmia, 978, 979
of remittent fever, 600
of rabies and hydrophobia, 900
of relapsing fever, 418-422
of rötheln, 587
of rubeola, 575
of scarlet fever, 532
of simple continued fever, 234
of symptomatic parotitis, 627
of typhoid fever, 311-314
of typho-malarial fever, 616
of typhus fever, 358, 359
of vaccinia, 464
of varicella, 483
of variola, 447
of varioloid, 444
of yellow fever, 648

Diaphoretics, use of, in yellow fever, 649

Diarrhoea in cerebro-spinal meningitis, 814
in cholera, 738
results, 738
treatment, 760
in mild scarlet fever, 503
in pyæmia, 975
in relapsing fever, 405
in rubeola, treatment, 581
in septicæmia, 977
treatment, 983
in typhoid fever, 287
treatment, 331

Diarrhoeal diseases from impure water, 182

Diathesis, 127
hereditary, transmission, 130

Diet in anthrax, 944
in beriberi, 1042
in cerebro-spinal meningitis, 834
in cholera, 763
in convalescence, 206
in erysipelas, 639
in glanders, 924
in influenza, 874
in relapsing fever, 430
in pertussis, 848
in puerperal fever, 1036
in pyæmia, 982
in rubeola, 579
in typhoid fever, 323
in typho-malarial fever, 619
in typhus fever, 362
in yellow fever, 654
of convalescence, 206

Digestion, condition of, in cerebro-spinal meningitis, 814

Digestive tract, condition of, in glanders, 921
in idiopathic parotitis, 623

Digitalis, use of, in puerperal fever, 1033
in relapsing fever, 428
in scarlet fever, 543
in typhoid fever, 330
in yellow fever, 651

DIPHTHERIA, 656
Synonyms, 656
Definition, 656
History, 656 _et seq._
Panum's view regarding relation of bacteria to, 667
Etiology--Age, influence of, on causation, 680
Sex, influence of, on causation, 680
Causes of frequency of, in childhood, 680
Pharyngeal, buccal, and nasal catarrh a cause of, in children, 680
Physiological causes of, greater frequency in childhood, 681
Family predisposition, 681
Thermometric and barometric changes a cause, 682
Season as a cause, 682
Filth as a cause, 682
Polluted air as a cause, 682
water as a cause, 683
milk as a cause, 683
Contagiousness, 678
Modes of transmission of poison, 678
In the lower animals, 683
Transmission of, from lower animals to man, 683
Artificial production of membrane, 684
Invasion, 676
duration of incubation period, 679
Symptoms--Prodromal stage, 667
duration, 667
localized redness of mucous membranes, 667
Different manifestations of diphtheritic process, 668
Severe form, 668
appearance of membrane in severe form, 668
Gangrenous condition of membrane, 669
Swellings of glands at angle of jaw as sign of invasion of nasal
cavities, 669, 670
Mode of invasion of nasal cavities, 669
Mode of spread to nasal cavities, 669
Nasal form, 669
Conjunctival form, 670
Aural form, 670
Laryngeal form, 671
Formation of membrane in larynx, 671
Tracheal and bronchial forms, 671
primary form, 672
Oral form, 672, 673
Intestinal form, 673
Of wounds, 673
Eruption of, 674
Vulvar and vaginal forms, 674
In puerperal women, 674
Vesical form, 674
Placental, 674
Liability of open wounds, 672, 679
Tendency to second attacks from chronic nasal and pharyngeal catarrh
following, 670
Complications and sequelæ, 672
complicated by fibrinous pneumonia, 672
by broncho-pneumonia, 672
by erysipelas, 673
by urticaria and purpura, 674
by kidney affections, 674
by albuminuria, 674
by granular degeneration of blood, 675
by cardiac degeneration, 675
by symptoms of cardiac degeneration, 675
by embolism, 675
by acute endocarditis, 675
by leucocythæmia and Hodgkin's disease, 675
by nervous diseases, 675
by paralysis, 676
seat of, 676
date of appearance, 676
fatty degeneration and atrophy following, 676
sensory, 676
Secondary form, 671
Morbid anatomy--characters of the membrane, 685
Mode of formation of membrane, 685
Varieties of membrane in, 686
Rindfleisch's definition of diphtheritic inflammation, 686
Changes in the heart, 686
fatty and granular degeneration, 686
endocarditis, 687
cardiac thrombi, 687
Changes in lungs, 687
Spleen, 687
Liver, 687
Kidneys, 687
Muscles, 687
Lymphatic glands, 687
Mucous membranes, 688
Influence of different mucous membranes upon characters of false
membrane, 688
epithelia upon growth and spread of false membrane, 688
Changes in intestines, 689
nervous system, 689
Diagnosis--significance of localized pharyngeal injection, 689
From muguet or thrush, 690
Follicular stomatitis, 690
Significance of glandular swelling, 690
lymphadenitis in nasal form, 690
Of laryngeal form, 691
Significance of absence of fever, 691
Of paralysis, 691
Prognosis--symptoms indicating favorable, 692
unfavorable, 692
Significance of glandular swelling, 692
In nasal, 692
Of fetid and putrid discharges, 693
Of epistaxis, 693
In laryngeal, 692
In tracheal, 692
Of tracheotomy, 692
significance of state of pulse after, 692
of dry respiration after, 692
of temperature-range after, 692
of character of membrane, 692
Influence of temperature, 693
state of pulse, 693
complications, 693
bronchitis and pneumonia, 693
endocarditis, 693
albuminuria, 693
affections of sensorium, 693
purpura, 693
icteric discoloration of skin, 693
Of relapses, 694
Treatment--hyperpyrexia, 694
Reflex symptoms, 694
Vomiting, 694
Futility of expectant, 694
Use of stimulants, 694
Amount of stimulants necessary, 695
Importance of general treatment, 695
Futility of venesection, 695
Prophylactic, 696
Danger of self-infection, 696
Prevention of self-infection, 696
Isolation, 696
Closure of schools and public places during epidemics, 697
Disinfection, 698
Special, 701
Local, 701, 709
by steam, 701
Use of water, 702
Ice and cold, 702
Cold baths, 702
Mode of applying cold, 702
Contra-indications to use of cold, 703
Solvents of pseudo-membrane, 703
Use of lime-water, 703
Slaking lime, 703
Lactic acid, 703
Pepsin, neurin, and chinolin, 703
Papayotin, 703
Pilocarpine, 704
objections to, 704
Turpentine inhalations, 704
Ammonium chloride, 704
Mercury, 705
Tincture of chloride of iron, 706
Carbolic acid, 707
Salicylic acid, 707
Quinia, 708
Bromine, 708
Boric acid, 709
Sodium salicylate, 709
Ozone, 709
Sulphur and cubebs, 709
Chlorate of potassium, 699
Dose of chlorate of potassium, 700
Danger in large doses of chlorate of potassium, 701
Mechanical removal of membrane, 709
Cauterization of membrane, 709
Glandular swellings, 710
Abscess of glands, 710
Of nasal form, 710
danger of permitting sleep in, 712
local applications, 710
Of conjunctival form, 712
Of laryngeal form, 712
use of emetics, 712
Of paralysis, 713
by strychnia, 713
by electricity, 713
artificial alimentation, 713
Of cutaneous form, 713

Diphtheria, complicating rubeola, 573
scarlet fever, 514
of genitalia in puerperal fever, 1002

Diphtheritic endometritis, 987
exudations, complicating rubeola, 735
membrane, cauterization, 709
mechanical removal, 709
conjunctivitis, 670
treatment, 712
inflammation, causes, 51
distinguished from diphtheria, 50
paralysis, treatment, 713
pock in vaccinia, 463

Disease, 35
Causes, 125, 175
arsenical poisoning, 193
climate, 185
cold, 133
contagion, 135, 200
epidemic influences, 135
errors of diet, 135
exciting, 125
exercise, abnormal, 134, 198
deficient, 135
functional, 134
habitation, 186
heat, 133
hereditary, 132
humidity of atmosphere, 133
improper clothing, 198
impure air, 177
ice, 185
water, 182
ingestive, 135
intemperance, 197
mental, 204
minute organisms, 141
predisposing, 125
pre-natal, 126, 175
poisons and misuse of medicines, 135
soil, condition of, 187
Definition of, 135
Elevation of site, influence of, 134
Means of discovery, 175
Abdominal, hot climate as a cause, 133
Respiratory, cold as a cause, 133
Prevention, 175
Respiration in, 156
Theory of--bioplastic, 140
chemical, 138, 140
fermentation, 138
germ, 138
points of objection, 142
undecided state, 147
Zymotic, table of, 136

Disinfectants, varieties, 202

Disinfection in anthrax, 937, 943
in cholera, 758
in diphtheria, 698
of glanders, 925
in the plague, 784
in puerperal fever, 1025, 1028
in pyæmia and septicæmia, 980
in scarlet fever, 201, 538
in typhus fever, 362
methods, 201
practical difficulties, 201
principles, 201

Dissecting poison, relation of, to causation of puerperal fever, 1018
wounds, relation of, to causation of septicæmia, 962

Dissemination of influenza, 863
in typhoid fever, 249
of puerperal fever by physicians, 1018

Diuretics, use of, in scarlet fever, 555
in wet beriberi, 1042

DRAINAGE AND SEWERAGE, 213
Back, ventilation of traps, 221
Disposal of liquid wastes by irrigation, 225
Frequency of leakage in waste-pipes, 222
Necessity of, in prevention of typhoid fever, 321
Of houses, 188
Necessity of abundant water-supply in, 220
Of soil, 226
Perfect, fundamental requirements, 213
Removal of human excrement, 215
of liquid household wastes, 220
Varieties of grease-traps, 221
Ventilation of waste-pipes, 223

Drainage-pipes, effects of large traps, 220
of too large bore, 220
of vertical position, 220

Drinking-water as a medium of disseminating typhoid fever, 248
propagation of cholera by, 723

Dropsies, 67-71

Drugs, use of, in the plague, 784

Dry form of beriberi, symptoms, 1040
treatment, 1043

Duration of cerebro-spinal meningitis, 818
of dengue, 882
of anthrax, 940, 941
of acute form of glanders in horses, 915
of chronic form of glanders in horses, 915
of acute form of glanders in man, 921
of chronic form of glanders in man, 922
of influenza, 865
of malignant scarlet fever, 508
of mild scarlet fever, 506
of prodromal stage of rubeola, 565
of remittent fever, 602
of rabies and hydrophobia, 900
of septicæmia lymphatica, 1012

Dysentery complicating relapsing fever, 406
typhus fever, 355

Dysphagia, significance of, in general diagnosis, 162

Dyspnoea, causes, 157

E.

Ear, affections of, in rubeola, treatment, 581
diseases of, complicating rubeola, 570
displacement of lobe in idiopathic parotitis, 624
internal, lesions of, in cerebro-spinal meningitis, 824
lesions of, in pyæmia, 967
in symptomatic parotitis, 626
middle, suppuration of, in cerebro-spinal meningitis, 811
symptoms of diphtheria, 670

Ears, significance of appearance of, in general diagnosis, 151

Early stages of yellow fever, treatment, 649

Earth-closets, 218

Effluvia, offensive, symptoms due to, 181

Effusions, 67
causes, 68-71
distinguished from exudations, 67

Elaterium, use of, in wet beriberi, 1042
in dry beriberi, 1043

Electricity, use of, in diphtheritic paralysis, 713

Elevated temperature as a cause of typhoid fever, 246

Emaciation, causes, 160
significance of, in diagnosis, 159

Emboli, action of, in production of metastatic abscesses in pyæmia,
967

Embolism, 62
complicating diphtheria, 675
from septic thrombus, 66
hemorrhagic results, 64, 65
in typhoid fever, treatment, 335
mechanical effects, 63
necrosis from, 64, 65
results, 64
softening, cerebral, from, 65
symptoms, 66

Embolus, 62
arterial, 63
venous, 63
terminations, 65

Emetics, use of, in cerebro-spinal meningitis, 830
in cholera, 765
during cold stage of intermittent fever, 595
in influenza, 876
in laryngeal diphtheria, 712
in pertussis, 845

Emphysema, aggravation of, by influenza, 870
significance of, in general diagnosis, 159

Endocarditis, acute, complicating diphtheria, 675
in diphtheria, 687
in puerperal fever, 990

Endo- and pericardium, lesions of, in septicæmia, 972

Endocolpitis in puerperal fever, 986, 1005

Endometritis in puerperal fever, 986

Enthetic febrile diseases, hereditary nature, 130

Epidemic causation of disease, 135

Epidemics of rubeola, frequency, 560
frequency in the new-born, 563

Epiglottis, symptoms of diphtheria, 671

Epistaxis in relapsing fever, 393
complicating rubeola, 570
in remittent fever, 602
in rubeola, treatment, 580
in typhoid fever, 273
treatment, 335

Epithelia, influence of different, in spread of diphtheritic membrane,
688

Ergot, use of, in cerebro-spinal meningitis, 833

Ergotine, use of, in pyæmia, 982

Eruption, absence of, in rubeola, 568
causes of absence of, in mild scarlet fever, 505
in cerebro-spinal meningitis, 816, 817
in dengue, 881
in diphtheria, 674
in influenza, 866
in malignant scarlet fever, 507
in mild scarlet fever, 504
in pyæmia, 974
in relapsing fever, 376
in rötheln, 585, 586
in rubeola, 566
peculiarities in character, 569
in seat, 509
relapses, 570
retrocession of, in rubeola, treatment, 580
in tubercular form of leprosy, 789
in typhoid fever, 273
in typhus fever, 351
in varicella, 487
in variola, 437
characters, 438
position, 438
in varioloid, 444

Eruptive stage of rubeola, duration of, 567
symptoms of, 565
of variola, treatment, 452

ERYSIPELAS, 629
Definition, 629
Synonyms, 629
Classification, 629
History, 629
Etiology, 629
Unity of the origin, 629
Age and sex as a cause, 630
Season as a cause, 630
Contagiousness, 630
Nature of contagion, 630
Manner of propagation, 630
Relation to childbed fever, 630
Symptoms--initial, 631
Characters of cutaneous lesions, 631
Course of cutaneous lesions, 631
Severe varieties of cutaneous lesions, 632
Migration of cutaneous lesions, 632
Swelling of integument, 632
Starting-point of cutaneous lesions, 632
Physiognomy, 632
Condition of tongue, 633
of fauces and buccal membrane, 633
General symptoms of grave form, 633
pulse, 633
temperature, 633
Occurrence of gangrene, 633
Resolution, 633
Desquamation, 633
Complications and sequelæ, 633
Complicated by lymphangitis and adenopathy, 634
By pneumonia, 634
By pleuritis, 634
By inflammation of joints, 634
By inflammations of serous membranes, 634
By pyæmia and septicæmia, 634
By eye diseases, 634
Followed by seborrhoea of scalp, 633
By loss of hair, 633
Modification of previous skin disorders, 634
Chronic forms, 634
Variety and nature of chronic forms, 634
Morbid anatomy, 635
Changes in skin, 635
Viscera, 635
Mucous surfaces, 635
Diagnosis, 635
From dermatitis, 636
From eczema, 636
From erythema, 636
From pemphigus, 636
From scarlet fever, 636
From urticaria, 636
Prognosis--symptoms indicating unfavorable, 636
Treatment--preventive, 636
Hygienic, 637
General, 637
Hyperpyrexia, 637
Delirium, 637
Local, 637
Value of abortive, 638
Surgical, 638
Mouth complications, 638
Nasal complications, 638
Abscesses, 638
Value of expectant, 639
Convalescence, 639
Diet, 639
Use of quinia, 637
tincture of the chloride of iron, 637

Erysipelas, complicating diphtheria, 673
typhus fever, 355
vaccination, 469
variola, 445
relation of, to puerperal fever, 1002

Etiology, general, 125
of anthrax in animals, 928
in man, 939
of beriberi, 1038
of cerebro-spinal meningitis, 801
of cholera, 720
of dengue, 883
of diphtheria, 680
of erysipelas, 629
of glanders in horse, 911
in man, 919
of idiopathic parotitis, 620
of influenza, 859
of leprosy, 787
of pertussis, 838
of the plague, 774
of puerperal fever, 1013
of pyæmia, 955
of rabies and hydrophobia, 887
of relapsing fever, 370
of remittent fever, 598
of rötheln, 583
of rubeola, 557
of scarlet fever, 487
of septicæmia, 960
of septo-pyæmia, 963
of simple continued fever, 232
of symptomatic parotitis, 625
of typhoid fever, 242
of typhus fever, 341
of varicella, 481
of variola, 435
of yellow fever, 640

Eucalyptus, use of, in typhoid fever, 331

Excision of cicatrix for prevention of hydrophobia, 908
of primary nucleus in anthrax, 943

Exciting cause, mechanical nature of, in symptomatic parotitis, 626
of the plague, 775
of typhoid fever, 248
of typhus fever, 343

Excrement, human, disposal of, by privy-vaults, 219
dry conservancy, 218 _et seq._
removal of, by water-carriage, 215

Exercise, abnormal, as a cause of disease, 134
amount necessary for health, 198
as a part of a systematic education, 199
deficiency of, a cause of disease, 135
Du Bois Reymond's definition, 198
importance of, in preservation of health, 198
relation of, to mental work, 199

Expectant treatment of erysipelas, value, 639

Expectoration, significance of, in diagnosis, 158

External anthrax, localized, 935

Exudation, distinction from transudation, 42
in inflammation, 42
in peri- and parametritis of puerperal fever, 1007
in pelvic peritonitis, 989

Eye, affections of, following cerebro-spinal meningitis, 819
in rubeola, treatment, 581
condition of, in cerebro-spinal meningitis, 810
diseases of, complicating erysipelas, 634
rubeola, 571
variola, 445
lesions of, in cerebro-spinal meningitis, 824
in pyæmia, 967

Eyes, appearance of, significance in general diagnosis, 151

F.

Face, appearance of, in typhus fever, 348

Family predisposition to diphtheria, 681

Faradization, use of, in rabies and hydrophobia, 907

Farcy, 909

Fatigue as a cause of typhus fever, 342

Fat, sources of, in the body, 74

Fatty degeneration, 74
causes, 78
following diphtheritic paralysis, 676
infiltration, 76
metamorphosis, 74, 79

Fauces, condition of, in cerebro-spinal meningitis, 814
in erysipelas, 633
in malignant scarlet fever, 508
in typhoid fever, 286
inflammation of, complicating rubeola, 571
significance of appearance of, in general diagnosis, 152

Faucial and nasal mucous membrane, condition of, in mild scarlet
fever, 504

Febrifuge, use of, in relapsing fever, 428

Febrile stage of grave form of the plague, 778

Fermentation theory of disease, 138

Fever, agents producing heat in, 40, 41
definition, 38
inflammatory, 37
distinguished from idiopathic, 37
influence of vaso-motor system on production of heat in, 39
intermittent, 592
malarial, 589
pernicious malarial, 605
puerperal, 984
relapsing, 369
remittent, 598
sanitary effects, 41
scarlet, 486
secondary, in variola, 439
simple continued, 231
symptoms, 38
temperature, 38-40
traumatic, 37
typho-malarial, 614
typhoid, 237
typhus, 338
yellow, 640

Fibrinous degeneration, 80
inflammation, 49

Filtering power of soil, 187

Filth as a cause of cholera, 721
diphtheria, 682
the plague, 774
relapsing fever, 370

Foetus, effects of maternal impression upon, 131

Fomites, propagation of cholera by, 721
special, of cholera, 723

Food, adulterations, 197
appetite as a guide to necessary amount, 195
as a cause of disease, 195
infants, 196
patient's sensations as a guide to choice of, in disease, 205
popular errors in regard to, 195
to overeating, 195
preparation of, necessity of a physician's knowledge of, 196
proper, necessity of, in prevention of pyæmia and septicæmia, 980
transmission of anthrax by, 929

Formad on peculiarities of scrofulous habit, 101

Forms of anthrax in animals and man, 934, 940
of leprosy, 789
of the plague, 777
of rabies, 895
of relapsing fever, 395
of vaccine, 476

Fourth ventricle, lesions of, in cerebro-spinal meningitis, 824

Frænum linguæ, ulceration of, in pertussis, 841

Frequency of puerperal fever, 984
of typho-malarial fever, 616

Frictions, use of, in dry beriberi, 1043

Frontal pains in influenza, 867

Fruit, propagation of malaria by, 591

Fulminant form of the plague, 779

Furious form of rabies, 896

Furuncles, complicating variola, 445

G.

Gait, peculiarity of, in beriberi, 1039

Gall-bladder, lesions of, in cholera, 746
in typhoid fever, 266

Gangrene, 56
complicating vaccination, 468
following typhoid fever, 293
typhus fever, 355
in erysipelas, 633
in symptomatic parotitis, treatment of, 628
of neck, complicating scarlet fever, 512
pulmonary, complicating relapsing fever, 404

Gangrenous affections following rubeola, 574

Gastro-intestinal canal, condition of, in dengue, 881
condition of, in yellow fever, 644
lesions of, in anthrax, 936
in influenza, 872
in rabies and hydrophobia, 902
in relapsing fever, 413
symptoms in influenza, 866
in mild scarlet fever, 505
in malignant scarlet fever, 507
of septicæmia lymphatica, 1011

Gelsemium, use of, in yellow fever, 651

GENERAL ETIOLOGY, 125

General dropsies, 71
treatment of erysipelas, 639
of glanders in horse and man, 919, 920

Genitalia, gangrene of, complicating variola, 446

Geographical distribution of anthrax, 926
of beriberi, 1038
of glanders, 909
of rabies and hydrophobia, 886
of relapsing fever, 369
of typhoid fever, 241

Germ, specific, of glanders, nature of, 914
of rabies and hydrophobia, 892
point of election of, 892

Germ-theory of disease, 138
of scarlet fever, 488

Giddiness, significance of, in general diagnosis, 166

GLANDERS (FARCY), 909
Synonyms, 909
Definition, 909
History, 909
Geographical distribution, 909
Etiology--Contagiousness, 911
Specific nature, 911
Predisposing causes, 912
Ill-health, relation of, to causation, 912
Cold and damp stables, relation of, to causation, 912
Debility from chronic diseases, relation of, to causation, 912
Infection, channels of, 913
Particular nature of the germ, 914
Virulence of the germ, 914
Modes of culture of germ, 914
Demonstration of bacillus of, 914
Symptoms--in horses, 914
Acute form, 914
Incubation period, 914
Mode of onset, 914
Local lesions, 915
Appearance of nostrils, 915
of lymphatics, 915
Enlargement of joints, 915
Appearance of ulcers, 915
Mode of death in, 915
Chronic form, 915
Premonitory symptoms, 915
Condition of general health, 915
Local lesions, 915
Lymphatics, 915
Bronchial and pulmonary form, 916
Acute cutaneous form (farcy), 916
Local lesions, 916
Chronic cutaneous form (chronic farcy), 916
Local lesions, 916
Duration, 915
Morbid anatomy, 916
Nasal lesions, characters of, 917
Pulmonary lesions, characters of, 917
Cutaneous lesions, characters of, 917
Diffuse glanderous swellings, 917
of nose, 918
of lungs, 918
of muscles, 918
Diagnosis, 918
Value of inoculation in, 918
Prognosis, 918
Unfavorable nature of, 918
Treatment--in animals, 918
Not commendable, 918
Local, 918
General, 919
Diet in, 919
Preventive, 919
Extermination of disease in animals, 919

_Glanders in Man_, 919
History of, 919
Etiology, 919
Modes of infection, 919
immediate, 919
mediate, 920
Influence of occupation, 920
Influence of ill-health, 920
Symptoms--incubation period, 920
Appearance of wound, 920
General, 920
Mode of onset, 920
Character and seat of local lesions, 921
Appearance of sores, 921
Condition of nasal mucous membrane, 921
of submaxillary glands, 921
of conjunctiva, 921
Digestive tract, 921
Nervous system, 921
Temperature in, 921
Pulse in, 921
Chronic form, 921
General, 921
Local, 921
Cutaneous lesion, 922
Respiratory lesions, 922
Lymphatic glands, 922
Digestive tract, 922
Convalescence, 922
Duration of acute forms, 921
of chronic forms, 922
Morbid anatomy--changes in mucous membranes, 922
Lungs and pleuræ, 922
Gastro-intestinal tract, 922
Spleen and liver, 922
Joints, 922
Bones, 922
Brain and membranes, 923
Microscopy of lesions, 923
Diagnosis, 923
Pathognomonic signs in, 923
From rheumatic fever, 923
Chronic form, from pyæmia and septicæmia, 923
From syphilis, 924
From miliary tuberculosis, 924
Presence of bacillus not conclusive, 924
Value of inoculation in, 924
Prognosis--unfavorable nature of, 924
Treatment--External cases, 924
Erysipelatoid swellings, 924
Abscesses and tumors, 924
Nasal ulcers, 924
Importance of general treatment, 924
Use of antiseptics, 924
Diet, 924
Preventive, 925
Extinction of affection in animals, 925
Necessity of disinfection, 925

Glanderous swelling, diffuse, 917

Glands at angle of jaw, swelling of, symptomatic of nasal invasion, in
diphtheria, 669, 670

Glandular abscesses in diphtheria, treatment, 710
degenerations, 72
swellings in diphtheria, treatment, 709

Glycosuria, complicating relapsing fever, 410

Gout, hereditary nature, 127

Granuloma, 120, 124

Grave forms of cholera, physiognomy, 734
stools, 733
symptoms, 732
of the plague, 777
of relapsing fever, 395

Grease-traps, varieties, 221

GROWTHS, MORBID, 105

Gums, significance of state of, in general diagnosis, 151

H.

Habits, depressing, as a cause of cerebro-spinal meningitis, 802

Hæmatemesis, significance of, in general diagnosis, 163
in relapsing fever, 390

Hæmatoidin, 91

Hæmatoma, 115, 122

Hæmaturia in relapsing fever, 390

Hæmoglobin, 90

Hæmophilia, hereditary nature, 129

Hæmoptysis, significance of, in general diagnosis, 163

Hæmostatics, use of, in yellow fever, 652

Hair, appearance of, in typhoid fever, 275
loss of, following erysipelas, 633

Headache in cerebro-spinal meningitis, 808
in idiopathic parotitis, 624
in influenza, 867
treatment, 874
in relapsing fever, 383
in typhoid fever, 277
treatment, 334
in typhus fever, 348
treatment, 366

Health, importance of exercise in preservation, 198

Health-resorts, disease from, 185

Hearing, impairment of, following cerebro-spinal meningitis, 819
disorders of, in relapsing fever, 400
modifications of, in typhoid fever, 279
significance of, in general diagnosis, 166

Heart, alterations of, in beriberi, 1041
condition of, in beriberi, 1040
in cholera, 737
in pyæmia, 976
in typhus fever, 351
disease, complicating influenza, 870
lesions of, in cholera, 746
in diphtheria, 686
in relapsing fever, 411
in septicæmia, 972
in typhoid fever, 267
in typhus fever, 357
and blood-vessels, lesions of, in rabies and hydrophobia, 902
palpitation of, in beriberi, 1039

Heart-clot, complicating relapsing fever, 402
rubeola, 672
scarlet fever, 523

Heat as a cause of disease, 133
use of, in cholera, 769

Hemorrhages in dengue, 882
in hemorrhagic form of pernicious malarial fever, treatment, 612
in remittent fever, treatment, 605
in yellow fever, 646
treatment, 651
intestinal, in typhoid fever, 287, 288
treatment, 332

Hemorrhagic form of pernicious malarial fever, 609
causes, 610
seat of hemorrhages, 610
symptoms, 611
treatment, 612
of scarlet fever, 509
of variola, treatment, 454
infarction, 64
rubeola, 569
small-pox, 442
variola, morbid anatomy of pock in, 447

Hepatic abscess following typhoid fever, 295

Heredity as a cause of disease, 175
influence of, on marriage, 176
relation of, to life insurance, 175
as a cause of leprosy, 787

Hereditary diathesis, transmutation, 130
nature of syphilis, 127
of non-malignant morbid growths, 129
of nervous diseases, 129
of organic disease, 129
of rickets, 128
predisposition to disease, 126

Herpes labialis, complicating influenza, 874

Hiccough in cholera, 762
in relapsing fever, 405
significance of, in general diagnosis, 158

Histoid tumors, 116

History of anthrax in animals and man, 926, 939
of beriberi, 1038
of cerebro-spinal meningitis, 796
of cholera, 715
of dengue, 879
of diphtheria, 656
of erysipelas, 629
of glanders in horses, 909
in man, 919
of influenza, 852 _et seq._
of pertussis, 836
of rabies and hydrophobia, 886
of relapsing fever, 369
of rötheln, 582
of rubeola, 557
of pyæmia and septicæmia, 945-952
of scarlet fever, 486
of simple continued fever, 231
of typhoid fever, 238
of typhus fever, 338
of vaccination, 465
of vaccinia, 456
of varicella, 481
of variola, 434

Hodgkin's disease, complicating diphtheria, 675

Horse-pock vaccine, 473

Hospitals for infectious diseases, necessity, 203

Hospital, maternity, advantages, 1021

Hot stage of intermittent fever, treatment, 595

House-drainage, 188
disconnection of, from sewer, 190
testing, 190

House-plumbing, 190

Houses, sanitary inspection, 187, 193

House-sewerage, 188
dangers to health from, 189, 191
examination of a system, 188
main points in a good system, 191
peppermint-test for defects, 190

Human excrement, removal of, by drainage, 215

Humanized and animal vaccine, relative merits, 473
vaccine, points of superiority, 473

Humidity of air as a cause of disease, 133

Hunger, influence of, on causation of rabies and hydrophobia, 888

Hyaline degeneration, 80

Hydro-bilirubin, 91

Hydrocephalus, following cerebro-spinal meningitis, 819

Hydrochloric acid, local use of, in puerperal fever, 1028

Hydrophobia, 886

Hygiene, 173
importance of perfect, in cholera epidemics, 758
in pertussis, 848
public, relation of physicians to, 207

Hygienic treatment of erysipelas, 637
of hydrophobia, 906
of scarlet fever, 539
of typhoid fever, 322
of yellow fever, 654

Hygroma, 116, 122

Hyperpyrexia in diphtheria, treatment, 694
in erysipelas, treatment, 637
in puerperal fever, treatment, 1032
in relapsing fever, treatment, 426
in rubeola, treatment, 579
in scarlet fever, treatment, 541
in typhoid fever, treatment, 327
in typhus fever, treatment, 364
in yellow fever, treatment, 651

Hypodermatic injection of anthrax swellings, 938, 943

I.

Ice, impure, as a cause of disease, 185
use of, in diphtheria, 702
in scarlet fever, 542

Idiopathic parotitis, 620

Idiosyncrasy as a cause of typhoid fever, 245
influence of, in causation of variola, 436

Ill-health, influence of, in causation of glanders, 912, 920

Impure air as a cause of disease, 177
evil effects of, 181
water, as a cause of disease, 182

Impurities of water, from living organisms, 184
nature, 184

Incubation of relapsing fever, 376
of scarlet fever, 492
of typhus fever, 346
of varicella, 481
of variola, 436
period of anthrax in animals, 934
in man, 940
of diphtheria, duration of, 679
of glanders in horse, 914
in man, 920
of influenza, 863
of intermittent fever, 592
of the plague, 777
of rabies and hydrophobia, 894
of rötheln, 585
of typhoid fever, 259
of yellow fever, 643
stage of idiopathic parotitis, duration, 621
of idiopathic parotitis, 621
of puerperal fever, 1004
of pyæmia, 973
of rubeola, 563

Indications for treatment of puerperal fever, 1028
of septicæmia, 982
of yellow fever, 649

Infants' food, 196

Infarction, hemorrhagic, 164

Infection, 200
channels of, in glanders, 913
modes of, in human anthrax, 939

Infiltration, albuminoid, 72
amyloid, 84
fatty, 76

INFLAMMATION, 37
Characteristics, 37
Heat, 37
Redness, 37
causes, 37
Pain, 41
causes, 41
Swelling, 41
causes, 41
Exudation, 42
Reuss on distinction of exudation from transudation, 42
Migration of white corpuscles, 42
Coagulation of exudation, 43
Changes in the blood-vessels, 43
Disturbance of functions, 44
Varieties of--hemorrhagic, 48
Diphtheritic, 50
Productive, 51
Catarrhal, 52
Phlegmonous, 52
Acute, 53
Chronic, 53
Interstitial, 53
Parenchymatous, 53
Termination, 54, 55, 56
Resolution, 54
New formations, 54
Cicatrization, 55
Abscesses, 56
Destruction of tissue, 56
Causes, toxic, 43
traumatic, 44
parasitic, 45
infectious, 45
constitutional, 46
trophic, 46
Course, 46
Sthenic and asthenic, 46
Serous, 47
Typhoidal, 47
symptoms, 47
Purulent, 48
Suppurative, relation of microbia, 48
Fibrinous, 49
of fauces, catarrhal and diphtheritic, complicating typhoid fever,
295
of neck, complicating parotitis, 511
simple, complicating vaccination, 468

Inflammations, serous, complicating typhus fever, 355

Inflammatory fevers, 37
form of typhus fever, 354
rubeola, 568

INFLUENZA--Definition, 851
Synonyms, 851
History, 852 _et seq._
Etiology, 859
Predisposing causes, 859
Age, relation of, to causation, 860
Social condition, relation of, to causation, 860
Sex, relation of, to causation, 860
Occupation, relation of, to causation, 860
Race, relation of, to causation, 860
Over-crowding and filth, relation of, to causation, 860
Season, relation of, to causation, 860
Climate, relation of, to causation, 860
Air, condition of, to causation, 860
Winds, relation of, to spread, 860
Mode of onset of epidemics, 860, 861
Duration of epidemics, 861
Exciting causes, 862
Specific poison, 863
Contagiousness, 862
Dissemination, 863
Relation of, to other epidemic diseases, 863
Incubation period, 863
Clinical history, 864
Variations in intensity of symptoms, 864
Symptoms of mild cases, 864
of severe cases, 864
Symptomatology, 865
Analysis of symptoms, 865
Fever, 865
Temperature, 865
Pulse, 866
Urine, 866
Skin, 866
Eruptions, 866
Gastro-intestinal system, 866
Nausea and vomiting, 866
Physiognomy, 866
Catarrhal symptoms, 866
Condition of mucous membrane, 866
Hoarseness, 867
Cough and dyspnoea, 867
Nervous system, 867
Headache, 867
Frontal pain, 867
Pains in limbs, 868
Pleurodynia, 868
Delirium, 868
Dizziness, 868
Sleeplessness, 868
Hebetude and torpor, 868
Muscular twitchings, 868
Mental condition, 868
Duration, 865
Complications and sequelæ, 868
Inflammations of lungs, 868
Bronchitis and capillary bronchitis, 868, 869
Catarrhal pneumonia, 869
Lobar pneumonia, 869
Localized pulmonary collapse, 869
Gangrene of lungs, 870
Pleurisy, 870
Pericarditis, 870
Laryngitis and chronic bronchitis, 870
Inflammation of middle ear, 870
Parotitis, 870
Herpes labialis, 870
Phthisis, 870
Emphysema, aggravation, 870
Old neuralgias, aggravation, 870
Heart disease, aggravation, 870
Bright's disease, aggravation, 870
Pregnancy, 870
Intermittent fever, 870
Morbid anatomy, 871
Essential lesions, 871
Appearance of respiratory tract, 871
Changes in gastro-intestinal tract, 872
Bronchial glands, 872
Lung tissue, 872
Pathology--Not a simple acute inflammation, 871
Specific character, 871
Diagnosis--From non-specific catarrhal affections, 872
From typhoid fever, 872
Prognosis--Influence of age, 872
pre-existing organic disease, 872
of character of epidemic, 872
Mortality, 872, 873
Variability in different epidemics, 873
Rate of, 873
Cause of death, 873
Treatment--preventive, 873
Mild forms, 874
Catarrh, 874
Headache, 874
Cough, 875
Use of quinine, 874
Opium, 874
Fat inunctions, 874
Diet, 874
Severe forms, 875
Indications for treatment, 875
High temperature, 875
Cough, 876
Sub-sternal and chest pains, 876
Use of diaphoretics, 875
Bloodletting, 875
Emetics, 876
Purgatives, 876
Quinine, 876
Mineral acids, 876
Expectorants, 877
Opium, 876
Alcohol, 877
Chloral, 877
Diarrhoea, 877
Debility, 877
Lung complications, 877
Diet in, 875
Convalescence, 878
Danger of depressing measures, 878

Inhalations, use of, in pertussis, 844

Initial stage of pertussis, 840
symptoms of yellow fever, 644

Injections, intravenous, use of, in cholera, 768
in hydrophobia, 908
in puerperal fever, 1029
vaginal, use of, in prevention of puerperal fever, 1026

Inoculation as a means of diagnosis in glanders, 918
in hydrophobia, 902
as a prophylactic in anthrax, 937
in rabies and hydrophobia, 905
in scarlet fever, 536
of leprosy, 788
of rubeola, 559
of small-pox, 465

Insects, propagation of anthrax by, 929

Insomnia in typhoid fever, treatment, 334
in typho-malarial fever, treatment, 619
in typhus fever, treatment, 366

Inspection of houses, sanitary, 187

Insusceptibility to rabies and hydrophobia, 894

Intellect, impairment of, following cerebro-spinal meningitis, 819
following typhoid fever, 292

Intellectual condition in typhus fever, 348

Intemperance as a cause of cholera, 721
of disease, 197
of relapsing fever, 370
of typhoid fever, 245
of typhus fever, 342

Intermission in intermittent fever, 594
in relapsing fever, 381

INTERMITTENT FEVER, 592
Incubation period, 592
Symptoms--prodromal stage, 592
Paroxysm, 592
Cold stage, 592
theory of cause of cold stage, 593
Hot stage, 593
duration of hot stage, 593
relation of type to duration of hot stage, 593
Sweating stage, 593
Nausea and vomiting during paroxysm, 593
Intermission, 594
Duration of intermission, 594
Relative frequency of different types, 594
Convertibility of different types, 594
Morbid anatomy, 594
Treatment--cold stage, 594
Use of quinia, 595
Opium, 595
Emetics, 595
Hot stage, 595
Use of opium, 595
Quinia, 596
Purgatives, 596
Of convulsions, 597
Sweating stage, 597
Use of quinia, 597
Causes of failure of quinia, 597
Adjuvants to quinia in preventing return of paroxysms, 598
Use of nitric acid to prevent return of paroxysms, 598

Internal anthrax in animals, 934

Interstitial inflammation, 53

Intestinal anthrax in man, 941
canal, lesions of, in cholera, 743
catarrh, chronic, following rubeola, 574
complicating rubeola, 572
tract, lesion of, in typhus fever, 357

Intestines, lesions of, in diphtheria, 689
symptoms of diphtheria of, 673

Intravenous injection of warm water in hydrophobia, 908

Inunction in scarlet fever, 541

Inunctions, use of, in rubeola, 580

Invasion of cerebro-spinal meningitis, 806
of diphtheria, 676
of variola, 438
stage of grave form of the plague, 777
of idiopathic parotitis, duration, 621
treatment, 624
of variola, treatment, 452
of varioloid, 443

Iodine as a specific in typhoid fever, 336, 337

Iodoform, intra-uterine use of, in puerperal fever, 1025

Iron, persulphate, local use of, in puerperal fever, 1028
tincture of the chloride, use of, in diphtheria, 706
in erysipelas, 637
in yellow fever, 652

Irregular forms of scarlet fever, 508

Irrigation, disposal of liquid wastes by, 225

Irritability of nervous system in hydrophobia, 899

Irritants, influence of, in production of morbid growths, 108

Isolated glands, lesions of, in cholera, 745

Isolation in anthrax, 937
in diphtheria, 696
in the plague, 783
in rubeola, 578
in scarlet fever, 536
necessity of, in typhus fever, 361
principles of, in disease, 203

J.

Jaborandi, use of, in scarlet fever, 552
in yellow fever, 650

Jaundice in relapsing fever, 391
in septicæmia venosa, 1012
complicating typhoid fever, 295
typhus fever, 356
in remittent fever, 601
in yellow fever, 646

Joints, chronic diseases of, following rubeola, 574
condition of, in glanders in man, 920
inflammation of, complicating erysipelas, 634
lesions of, in pyæmia, 967
purulent inflammation of, in puerperal fever, 990
suppuration of, in pyæmia, 976
swelling of, in cerebro-spinal meningitis, 814
in relapsing fever, 400

Jugular veins, pulsation of, significance in general diagnosis, 156

Juniper gin, use of, in wet beriberi, 1042

K.

Kibbie's fever-cot, use of, in puerperal fever, 1034, 1035

Kidney affections, complicating diphtheria, 676
complications in hemorrhagic form of pernicious malarial fever,
treatment, 612

Kidneys, lesions of, in anthrax in animals, 937
in man, 942
in cholera, 746
in diphtheria, 687
in pyæmia, 969
in rabies and hydrophobia, 903
in relapsing fever, 414
in scarlet fever, 526
in septicæmia, 972
in typhoid fever, 268
in typhus fever, 357

Koch's investigation of bacillus tuberculosis, 99
of cholera bacilli, 745-749
of bacteria of puerperal fever, 997

L.

Lactic acid, use of, in diphtheria, 703

Lardaceous degeneration, 84

Laryngeal diphtheria, local treatment, 712
prognosis, 692

Laryngitis, complicating rubeola, 571
typhoid fever, 294

Larynx, inflammation of, complicating variola, 446
lesions of, in hydrophobia, 902
in relapsing fever, 413
in typhoid fever, 266
symptoms of diphtheria, 671

Latent form of typhoid fever, 300

Leeches, use of, in puerperal fever, 1031

LEPROSY, 785
Definition, 785
Synonyms, 785
History, 785
Etiology, 787
Heredity as a cause, 787, 788
Contagiousness, 788
Transmission, by inoculation, 788, 789
Sex as a cause, 789
Forms, 789
Symptoms--prodromal stage, 789
Duration of prodromal stage, 789
Tubercular form, 789
Local, 789
Eruptions, 789
Earlier eruptions, 790
Characteristic eruptions, 790
General, 790
Duration, 790
Anæsthetic form, 790
Local, 790
General, 791
Duration, 791
Morbid anatomy, 791
Changes in nerves, 791
Skin, 791
Bacteria, 792
Seat of bacteria, 792
Diagnosis, 792
Prognosis, 793
Treatment, 793
Futility of specific, in, 793
Indications, 793
Prophylaxis, 794
Segregation of afflicted, 794
Quarantine in, 794
Local, 794

Lesions characteristic of anthrax, 935

Lethargic form of rabies in dogs, 897

Leucocytes, death of, as a cause of thrombosis, 57
migration, 42

Leucocythæmia, complicating diphtheria, 675

Lime-water, use of, in diphtheria, 703

Limbs, significance of appearance in general diagnosis, 160

Listerine as a prophylactic in scarlet fever, 537

Liver, abscess of, following typhoid fever, 295
enlargement of, in pyæmia, 976
lesions of, in cholera, 745
in diphtheria, 687
in glanders, 918, 922
in pyæmia, 969
in remittent fever, 602
in relapsing fever, 414
in scarlet fever, 531
in typhoid fever, 265
in typhus fever, 357
in yellow fever, 649

Local dropsies, 71
lesions of glanders, 915, 921
symptoms of glanders in animals, 914
of glanders in man, 921
treatment of anthrax in animals, 938
of anthrax in man, 943
of diphtheria, 701, 709
of erysipelas, 637
of glanders in horse, 918
in man, 924
of pyæmia, 981
of septicæmia, 983

Lochial discharge, influence of, on causation of puerperal fever, 1015

Lung diseases, complicating influenza, 868
complicating influenza, treatment, 877

Lungs, gangrene of, in influenza, 870
hypostatic congestion of, in typhus fever, 353
lesions of, in cholera, 746
in diphtheria, 687
in glanders, 917, 922
in influenza, 872
in pyæmia, 968
in relapsing fever, 413
in septicæmia, 972
in typhoid fever, 266

Lymph, dried, use of, in vaccination, 477
of vaccinia, microscopical characters, 463
vaccine, proper time for collecting, 479

Lymphangitis, complicating erysipelas, 634
vaccination, 468

Lymphatic glands, condition of, in anthrax, 940
in glanders in horses, 915
in man, 921
in malignant scarlet fever, 508
in rötheln, 586
lesions of, in human anthrax, 942
in anthrax of lower animals, 935
in diphtheria, 687
in relapsing fever, 417
pigmentation of, 92

Lymphatics, as channel of entrance of poison of septicæmia, 963
lesions of, in symptomatic parotitis, 626

Lymphatic swellings, seat of, in grave form of the plague, 778
system, lesions of, in the plague, 781

Lymphoma, 120, 124

M.

Magnesium sulphate, use of, in wet beriberi, 1042

Malaria, 89
action of poison on system, 591
entrance into system, modes of, 591
communicability by drinking-water, 590
by fruit, 591
by milk, 590
conditions necessary to mature the poison, 589
duration of incubation of poison, 591
from impure water, 182
influence of moisture in production, 187
means of access of the poison, 590
nature of the poison, 589
non-interchangeableness of the poison, 591
ponderability of the poison, 590
production, 187
specific nature of poison, 591

MALARIAL FEVER, PERNICIOUS, 605
Definition, 605
Varieties, 606
Algid or congestive form, 606
Causes, 606
Frequency, 607
Cases illustrating clinical history, 606
Causes of death, 607
Mortality-rate, 607
Treatment, 607
General indications for treatment, 608
Use of ice and cold in treatment, 608
Opium, 608
Alcohol, 608
Comatose form, 608
Symptoms, 608
Previous condition of persons attacked, 609
Diagnosis from congestive form, 609
Treatment, 609
Hemorrhagic form of, 609
Causes, 610
Seat of hemorrhages, 610
Cases illustrating clinical history, 611
Treatment, 612
Indications for treatment, 612
Use of quinia, 612
Hemorrhages, 612
Renal complications, 613
Depurative, 613
Use of calomel and purgatives, 613

Malarial fevers, 589
definition, 589
nature of remittent fever, 598

Malignant anthrax oedema, 940
pustule, 926
tumors, 114

Mania following cerebro-spinal meningitis, 819

Maternity hospitals, advantages of, 1021

Marriages, influence of, hereditary, 176
of diseased persons, 176
transmission of hereditary proclivities by, 131

Marriages, consanguineous, 131

Marson's theory of multiple vaccination, 467

Masked forms of yellow fever, symptoms, 654

Maturation in variola, 439

Measles, 557
relations of, to idiopathic parotitis, 620

Mechanism of transudation, 68

Medical diagnosis, general, 148

Melanæmia, 92

Melanin, 92

Membrane, appearance of, in severe form of diphtheria, 668
diphtheritic, artificial production, 684
characters, 685
mode of formation, 685
varieties, 686
gangrenous condition of, in diphtheria, 669

MENINGITIS, EPIDEMIC CEREBRO-SPINAL, 795
Definition, 795
Synonyms, 795
History, 796
Etiology, 801
Seasons as a cause, 802
Meteorological agencies, 802
Localities, 802
Age, influence, 802
Sex, influence, 802
Depressing and debilitating habits, 803
Contagiousness, 803
Morbific principle, 803
Pandemic nature, 804
In the lower animals, 804
Types, 804
Forms, 805, 806
Symptoms--summary of, 806
Modes of onset, 806, 807
Individual, 808
Pain in the head, 808
spine, 808
Hyperæsthesia and anæsthesia of skin, 808
Spinal rigidity or opisthotonos, 809
duration of, 809
Convulsions, 809
Paralysis, 810
Aphasia, 810
Condition of eyes, 810
pupils, in, 810
strabismus, 810
blindness, 811
Deafness, 811
Suppurative inflammation of middle ear, 811
Physiognomy, 812
Delirium, 812
Coma, 812
Vertigo, 812
Debility, 813
Condition of tongue, 813
Nausea and vomiting, 813
Characters of matter vomited, 813
Appetite and digestion, 814
Thirst, 814
Constipation and diarrhoea, 814
Condition of fauces, 814
Urine, 814
Swelling of joints and limbs, 814
Respiration, 814
Pulse, 815
Temperature, 815
fluctuations of, 816
Eruptions, 816
irregularity of, 816, 817
petechiæ and ecchymoses, 816, 817
bullæ and pemphigus, 817
Cause of death, 818
Duration, 818
Convalescence, 819
characters, 819
cause of tardy, 819
Relapses, 820
frequency, 820
Sequelæ, 819
Followed by eye affections, 819
Impairment of hearing, 819
Deaf-mutism, 819
Impaired intellect and mania, 819
Hydrocephalus, 819
Paresis and paralysis, 819
Softening of brain, 820
Difficulty of speech, 820
Severe neuralgic pains, 820
Mortality of, 820, 828
variability of death-rate, 820, 828
influence of age upon, 828
Morbid anatomy, 820
General appearance of body after death, 820
Changes in the muscles, 821
in brain and membranes, 821
Changes due to congestion of brain and membranes, 821
to inflammation of meninges, 822
to softening of the brain, 823
Changes in pia mater, 821
in brain-tissue, 823
in spinal cord and membranes, 823
position of, 823
in internal and auditory apparatus, 824
Softening of fourth ventricle and auditory nerve, 824
Changes in eye and optic nerve, 824
in the viscera, 824
Absence of enlargement of spleen, 824
Changes in blood, 824
Amount of fibrine in blood before death, 825
after death, 825
Changes in blood-corpuscles, 825
Summary of pathology, 826
Diagnosis of, 826
From sporadic meningitis, 827
Functional and hysterical nervous affections, 827
Typhoid fever, 827
Typhus fever, 827
Prognosis of, 828
Symptoms indicating unfavorable, 829
favorable, 829
Imprudence of absolute, in, 829
Treatment, 829
Emetics, 830
Purgatives, 830
Futility of venesection, 830
Local depletion, 830
Cold applications, 830
Blisters, 830
Mode of using blisters, 831
Of coldness of skin, 831
Of collapse, 831
Use of alcohol, 831
Opium, 832
Value of opium, 833
Use of quinia, 833
Antipyretics, 833
Mercury, 833
Calabar bean, 834
Belladonna, 833
Ergot, 833
Potassium bromide, 834
Hydrate of chloral, 834
Potassium iodide, 834
Management of convalescence, 835
Diet in, 834

Meningitis, granular, following rubeola, 574

Menstrual disorders, complicating relapsing fever, 410
typhoid fever, 296

Menstruation, complicating typhus fever, 356
significance of abnormal, in general diagnosis, 165

Mental condition in hydrophobia, 899
in influenza, 868
in septicæmia lymphatica of puerperal fever, 1012
in typhoid fever, 277
disorders following the plague, 781
impressions, influence of, in causation of yellow fever, 643
overwork as a cause of typhus fever, 342
strain, symptoms due to, 205
work, relation of, to exercise, 199

Mercury, use of, in cerebro-spinal meningitis, 833
in diphtheria, 705

Metamorphosis, cheesy, 79
colloid, 83
croupous, 80
fatty, 74, 79
mucous, 82

Metastasis in idiopathic parotitis, 623, 624
treatment, 625
in pyæmia, pathology, 964
of tumors, 110

Methods of disinfection, 201
of vaccinating, 478

Metritis in puerperal fever, lesions, 987

Meteorism in typhoid fever, 286

Micro-organisms of puerperal fever, 1015
in pyæmia, blood-changes effected, 970

Microbes, as poison producers and carriers, 141
difficulty of separation of, from surrounding material, 146
liability to error from minuteness, 143

Microbia in inflammation, 45, 48

Micrococci, 141
in healthy bodies, 144

Microscopic organisms, classification, 141

Microscopy of glanderous lesions in man, 923

Migration of leucocytes, 42

Mild forms of cholera, 731
character of stools, 732
number of stools, 732
of influenza, treatment, 874
form of typhus fever, 354
of yellow fever, symptoms, 644

Milk, adulteration, 197
as a cause of disease, 197
as a medium of dissemination of anthrax, 929
of malaria, 590
of rabies and hydrophobia, 891
of scarlet fever, 491
of typhoid fever, 252
as a vehicle of bacillus tuberculosis, 105
polluted, as a cause of diphtheria, 683

Mind, state of, in relapsing fever, 384

Miscarriage, complicating typhus fever, 356

Modern conveniences questionable benefits, 215

Moral sense, perversion of, following typhoid fever, 292

Morbid anatomy, of anthrax in animals, 935
in man, 941
of beriberi, 1040
of cerebro-spinal meningitis, 820
of cholera, 741
of dengue, 882
of diphtheria, 685
of erysipelas, 635
of glanders in horses, 916
in man, 922
of idiopathic parotitis, 621
of influenza, 871
of intermittent fever, 594
of leprosy, 791
of pertussis, 843
of the plague, 781
of puerperal fever, 985
of pyæmia, 966
of pyæmia simplex, 970
of rabies and hydrophobia, 902
of relapsing fever, 413-417
of remittent fever, 602
of rubeola, 575
of scarlet fever, 530
of septicæmia, 971
of septo-pyæmia, 972
of simple continued fever, 235
of symptomatic parotitis, 626
of typhoid fever, 260
of typhus fever, 356
of vaccinal pock, 463
of varicella, 483
of variola, 446
of yellow fever, 649
growths, 105
classifications, 114, 122
Cohnheim's theory of origin, 106
influence of an irritant in production, 108
method of origin, 106
non-malignant, hereditary nature, 129
processes, 35

Morbific principle of cerebro-spinal meningitis, 803

Morphia, hypodermic use of, in beriberi, 1043
use of, in rabies and hydrophobia, 907

Mortality of anthrax in animals, 936
in man, 943
of cerebro-spinal meningitis, 820, 828
in cholera, 754
of glanders in man, 924
of influenza, 872
of pertussis, 841
of the plague, 780
of puerperal fever, 1020
of rabies and hydrophobia, 894
in relapsing fever, 422
of remittent fever, 599
of rubeola, 577
of scarlet fever, 534
of typhoid fever, 316-320
of typho-malarial fever, 616
of typhus fever, 360, 361
of yellow fever, 647, 648

Mouth, condition of, in idiopathic parotitis, 622
of mucous membrane of, in erysipelas, 633
complications in erysipelas, treatment, 638
symptoms of diphtheria, 672, 673

Mucous degeneration, 82
membranes of palate and fauces, appearance of, in prodromal stage of
rubeola, 564
condition of, in confluent small-pox, 441
in rötheln, 586
eruptions of varicella on, 483
influence of different, upon the character of diphtheritic
membrane, 688
lesions of, in diphtheria, 688
in glanders in man, 922
in rabies and hydrophobia, 902
in erysipelas, 635
localized redness of, symptomatic of prodromal stage of
diphtheria, 667
variolous pustules upon, 439
metamorphosis, 82
softening, 82

Multiple tumors, 110

Mumps, 620

Murmurs, arterial, in beriberi, 1040
cardiac, in beriberi, 1040

Muscles, alteration of, in beriberi, 1041
lesions of, in cerebro-spinal meningitis, 821
in diphtheria, 687
in pyæmia, 966
in typhoid fever, 267
of neck, suppuration of, in symptomatic parotitis, 626
voluntary, lesions of, in relapsing fever, 410

Muscular pains in yellow fever, 644
paralysis in beriberi, 1039
rigidity after cholera, 741
spasm, in typhoid fever, 279
tenderness in beriberi, 1039
tremor in typhoid fever, 279
in typhus fever, 349

N.

Nævi, vaccination as a means of destroying, 468

Nails, appearance of, in typhoid fever, 275

Nasal cavities, condition of, in malignant scarlet fever, 508, 520
mode of invasion of, in diphtheria, 669
complications in erysipelas, treatment, 638
diphtheria, local treatment, 710
prognosis, 692
form of diphtheria, symptoms, 669
lesions in glanders, 917
mucous membrane, condition of, in influenza, 866

Nationality in relation to relapsing fever, 371

Nature of puerperal fever, views concerning, 990-1004
of vaccinia, 455

Nausea, during intermittent fever paroxysm, 593
in cerebro-spinal meningitis, 813
in influenza, 866
in relapsing fever, 390
in rubeola, treatment, 581
in typhoid fever, 285
in typhus fever, 350
in yellow fever, treatment, 652
significance of, in general treatment, 162

Negroes, insusceptibility of, to yellow fever, 644

Neck, significance of appearance of, in diagnosis, 152

Necrosis from embolism, 64, 65

Neoplasms, 105

Nephritis, complicating scarlet fever, 525
in scarlet fever, treatment, 550-555

Nerves, lesions of, in leprosy, 791
in symptomatic parotitis, 626

Nervous diseases, complicating diphtheria, 675, 676
hereditary nature of, 129
influence of, upon susceptibility to rubeola, 561
symptoms in relapsing fever, 383-385
complicating scarlet fever, 510
of dengue, 882
of influenza, 867
of malignant scarlet fever, 507

Nervous system, chronic diseases of, following rubeola, 574
condition of, in cholera, 741
in remittent fever, 602
lesion of, in diphtheria, 689
in septicæmia, 972

Neuralgia, following cerebro-spinal meningitis, 820
in yellow fever, 644

Neuralgias, old, aggravation of, in influenza, 870

Neurine, use of, in diphtheria, 703

Nitric acid, use of, to prevent the return of intermittent fever
paroxysm, 598

Nitro-muriatic acid, use of, in anthrax, 938

Nodule, nasal, in glanders, 917

Nomenclature of pyæmia, 953
of septicæmia, 953

Nose, inflammation of, complicating variola, 445

Nostrils, condition of, in glanders in man, 921

Nourishment, necessity of, in typhus fever, 363

Nuisance, legal views as to what constitutes, 182

O.

Obesity, tendency to, following typhoid fever, 298

Obstetrical scarlatina, 498

Occupation, influence of, in causation of anthrax, 939
of glanders, 920
of influenza, 860
of typhoid fever, 244
of typhus fever, 343
relation of, to relapsing fever, 372

Odor of body, significance of, in general diagnosis, 159
of relapsing fever, 378