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Chapter III: Front Matter (3)

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Of the oil of roses, there is, properly speaking, only one genuine quality, with only little difference in odor, but with remarkable variation in the facility with which it congeals, which property is almost generally considered an essential proof of its being genuine, but without reason; as we have ascertained by much experience, during a long sojourn in the country where it is produced. Several reasons may contribute to this difference in congealing, but the chief one may be considered, the difference of soil, and method of preparation. We give our principal attention to the article, and have founded an establishment at Kissanlik, where it is chiefly produced, through which alone we make our purchases, and must do so, in order to have the attar genuine, as we have experienced, that all the essence without exception that is sold here, second hand, is far from pure.

The common method and the one now almost exclusively adopted of adulterating it, with geranium essence, may be known {48} to you, and that it really is the most in use, you may conclude, from the price of the genuine article having been for a long time much higher at the places of production, than the price of that which is sold as prime in Europe. This fact has only lately been noticed in Europe, therefore in the price current of Trieste, for instance, you will find the genuine article noted, beside the prime article, with a considerable difference of price. What at London is designated as prime quality, is only a mixture of 60 to 70 per cent. essence of rose, with 30 to 40 per cent. essence of geranium. Samples will also prove this to you, more clearly. The price of the genuine attar is, to-day, 22 3/4c. for an ounce, at 10 drachms, according to which the English price current may be understood; in six or eight weeks after the preparation of the new crop, we hope to buy cheaper, but at what rate we cannot yet judge, as this depends on the produce of the crop. There is some cheaper and adulterated, and which is only bought by ignorant persons. This oil comes by caravans from the interior of Asia, and in spite of all our inquiries, we could not succeed in getting any sure information, about the plant which produces it, or the method of preparation.

ON CHLOROFORM AS A SOLVENT.

BY M. P. H. LEPAGE, OF GISORS.

Hitherto, attention has been mainly directed to the manufacture of chloroform, and the study of its anesthetic properties. Many chemists, however, have casually noticed the power it possesses of dissolving essential oils, fixed fatty matters, camphor resins, (even those which dissolve with difficulty in alcohol and ether, such as copal resin, for example,) iodine, bromine, vegetable alkalies, india rubber insoluble in alcohol, and but slightly soluble in ether, and, finally, gutta percha, insoluble according to M. Vogel, in both these menstrua. {49}

Having lately had occasion to experiment with chloroform, upon a variety of substances, I have thought it might be useful, with a view to its further application, to make known the results obtained.

1. Resinous substances, gum mastic, colophony, elemi, balsam of tolu, benzoin, are very soluble cold, in all proportions of chloroform and their solutions in this liquid form varnishes, some of which might, I think, be usefully applied, when the price of chloroform shall be diminished.

Gum copal and caoutchouc dissolve equally and almost entirely in this liquid, but more easily hot than cold.

Amber, sandarac, and shellac, are only partially soluble in chloroform, whether hot or cold. The mixture of sandarac and chloroform separates into two layers; the lower one which holds in solution a certain quantity of resin, is fluid, whilst the upper one is of a gelatinous consistence.

Olibanum dissolves with difficulty in it, either hot or cold.

Gum guaiac and scammony resin, dissolve very easily in it; whilst on the contrary, pure jalap resin is insoluble; it becomes soft by contact with the liquid, and then floats on the top, as a pitch like mass. When the resin is very pure, the lower layer of chloroform has an amber color.

Gamboge and gum dragon’s blood, also yield some of their substance to chloroform. The solution of gamboge being of a magnificent golden yellow, and that of the dragon’s blood of a beautiful red, these two substances might be advantageously used as varnishes.

2. Fixed Fats. Oils of olive, œillettes, almond, ricinus, cod, rape, euphorbia, lathyris, croton tiglium, lard, tallow, the concrete oils of palm and cocoa, spermaceti, and probably all the fixed fats, dissolve remarkably and in all proportions in chloroform. As to wax, according to M. Vogel, six or eight parts of chloroform added to one part of this substance when pure, dissolve only .25, whence this chemist supposes, that whenever wax treated with this liquid in the above {50} named proportions, leaves less than .75, it may be considered as having been mixed with tallow or stearic acid.

I placed in a small tube, seven grammes of chloroform, and one gramme of _pure_ white wax, shaking the mixture violently, at the end of six or eight hours the piece of wax had entirely disappeared, and the contents of the tube resembled an emulsion. The whole was passed through a filter of the weight of one gramme. A transparent liquid passed, which, exposed to spontaneous evaporation, left a residuum of pillular consistence weighing twenty-five centigrammes; whilst the filter which retained the portion of undissolved wax, left to the action of the air, until it no longer lost weight, was found to weigh one gramme, seventy-five centigrammes. The result of this experiment therefore, confirms the statement of the learned chemist of Munich.

3. Volatile oils. All are soluble in chloroform.

4. Simple metalloid bodies. We already know that iodine and bromine are soluble in chloroform, I have further ascertained that phosphorus and sulphur are slightly so.

5. Immediate neutral principles. Stryacine, piperine, naphtaline, cholesterine, are very soluble in chloroform. Pricrotoxine, slightly so. Parafine will only dissolve when warm, and on cooling, again floats on the top of the liquid. Amygdaline, phloridzine, salicine, digitaline, cynisin, urea, hematin, gluten, sugar, &c., are insoluble in it.

6. Organic acids. Benzoic and hippuric acids are very soluble in chloroform. Tannin is but slightly soluble, tartaric, citric, oxalic and gallic acids are insoluble in it.

7. Organic alkalies. Quinine, pure veratrine, emetine and narcotine are easily soluble in chloroform. Strychnine dissolves pretty well in it, and the solution, even when not saturated (one décigramme to two grammes of chloroform, for instance,) deposits, in twenty-four hours, a number of little tuberculiform crystals, which may perhaps be a modification of this alkaloid (an isomeric state), for their solution in dilute acids has appeared to me less bitter, and less easily precipitable by {51} ammonia than that of ordinary strychnine. Brucine is also quite soluble in chloroform. Morphine and cinchonine are insoluble.

8. Salts of organic acids. Tartar emetic, the acetates of potash and soda, lactate of iron, citrate of iron, valerianate of zinc, and acetate of lead do not dissolve in chloroform.

9. Salts with organic bases. Sulphate and hydrochlorate of strychnine, are tolerably soluble in chloroform, whilst sulphate of quinine, hydrochlorate and sulphate of morphine are insoluble.

10. Haloid salts. Iodide and bromide of potassium, the chlorides of sodium, potassium and ammonia, the iodides of mercury and lead, the yellow prussiate of potash, the cyanides of mercury and potassium do not dissolve in chloroform. Chloride of mercury is very soluble.

11. Oxysalts. The iodates, chlorates, nitrates, phosphates, sulphates, chromates, borates, arseniates and alkaline hyposulphates are completely insoluble in chloroform. The same may be said of nitrate of silver, sulphate of copper, and probably of all the metallic oxysalts.

The above facts prove: 1st That chloroform dissolves, with a very few exceptions, all bodies soluble in ether; but as it dissolves copal, caoutchouc, &c., much better than this latter substance, this property will become serviceable when the price of chloroform shall be lowered.

2nd. That contrary to what was formerly believed, it dissolves shellac much less easily than alcohol.

3rd. That it may be employed instead of ether, to separate quinine from cinchonine, narcotine from morphine, guaiac resin from jalap resin, which substances are often found mixed together in commerce.

4th. That it dissolves in large proportions strychnine, brucine, and emetine, alkaloids, which are almost insoluble in ether.

5th. Finally, that it does not dissolve tartaric, citric, oxalic and gallic acids, amygdaline, phloridzine, salicine, digitaline, hematine, gluten, &c., all which bodies are soluble in alcohol, {52} nor the chlorides, bromides, iodides, or nitrates, salts, all soluble in the same vehicle.

I think it right also to add the following observation, because it tends to corroborate a fact recently stated in the _Journal de Chimie Médicale_, by my friend and former colleague, M. Aujendre, assayer at the mint of Constantinople, namely that chloroform possesses antiseptic properties. Having accidentally left in a half filled, but corked bottle, during a month (from April 10, to May 12), in my laboratory, where the variations of temperature are very frequent, some milk mixed with about a hundredth part of chloroform, I was rather surprised, on examining the milk, to find that it had preserved the fluidity and homogeneity of the liquid when freshly drawn, and that it could even be boiled without turning.—_Journal de Chimie Médicale in L’Abeille Médicale._

[NOTE.—Chloroform will preserve Anatomical and Pathological Specimens without changing their color, or apparently their texture.]—ED. N. Y. JOURNAL OF PHARMACY.

REPORT OF A JOINT COMMITTEE OF THE PHILADELPHIA COUNTY MEDICAL SOCIETY AND THE PHILADELPHIA COLLEGE OF PHARMACY, RELATIVE TO PHYSICIANS’ PRESCRIPTIONS.

(_Published by order of the Board of Trustees of the Philadelphia Coll. of Pharm._)

The joint Committees of the Philadelphia County Medical Society, and of the Philadelphia College of Pharmacy, appointed for the purpose of considering the means best adapted to prevent the occurrence of mistakes in the compounding of the prescriptions of Physicians by Apothecaries, beg leave to report that they have given to the subject all the attention that its importance demands, and present the following hints as the results of their joint deliberations. They have taken the liberty of adding, also, a few general hints on the relations that should exist between physicians and pharmaceutists.

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A. _In Respect to Physicians._

1. Physicians should write their prescriptions carefully and legibly, making use of good paper, and, whenever possible, of pen and ink. When obliged to write with a pencil, they should take the precaution to fold the prescription twice, so as to prevent its being defaced.

2. The nomenclature of the United States Pharmacopœia is becoming annually more in favor with pharmaceutists; a statement attested by the fact that 1500 copies of the book of Latin Labels for shop furniture, published by the Philadelphia College of Pharmacy, have been disposed of within three years. Physicians are also becoming more alive to the merits of our national Codex, and they are respectfully urged to familiarize themselves with its nomenclature, and to adhere to it strictly in their prescriptions.

3. The numerous treatises on Materia Medica, Pharmacy and the Practice of Medicine, of English origin, that are reprinted in this country, notwithstanding they are generally interlarded with the formulæ of our own Pharmacopœia, tend, nevertheless, very much to confuse the physician and apothecary, in the use and exact meaning of terms in prescriptions. To obviate the difficulties thus occasioned, the physician should, when he prescribes a medicine, which is not officinal, nor in common use, state on his prescription, either in a note at the bottom, or within parenthesis, following the article, the authority or work from whence it is derived, as “Griffith’s Formulary,”—“Ellis’ Formulary,”—“Braithwaite’s Retrospect,” etc.

4. Physicians would lessen the risk of errors in their prescriptions, and increase the chances of their detection should they be made, by observing the following hints.

1st. Write the name of the patient at the top of the prescription, unless a good reason prevents this being done; in which case, it should be expressed as for Mr. G—, Mrs. R—, or Mrs. S.’s child, or for Master T—, so as to convey to the apothecary some idea of the age of the patient. {54}

2d. The date and name of the physician or his initials, should always be appended, and, whenever practical, the dose and mode of administering the medicine directed.

3d. When an unusually large dose of an active medicine is prescribed, as opium, morphia, elaterium, strychnia, etc., let such names be put in _italics_, and the quantity or quantities repeated in writing enclosed within a parenthesis; thus:—R Morphiæ Sulphatis grs. vj. (six grains.) Div. in chart. vj.

4th. When an active substance is to be used externally, it should be so stated on the prescription; thus, “For external application”—“To be applied to the part as directed,” etc.

5th. The quantities of each article should be placed in a line with the name, and not below it and in using the Roman numerals, the _i_’s should be dotted correctly.

6th. The occasional practice of writing the directions intended for the patient in _latin_, and especially in abbreviated latin, is uncalled for, and attended with some risk; it is far safer to write them in English, and without abbreviation or the use of figures, unless these are well and distinctly formed.

B. _In Respect to the Apothecary._

1st. The apothecary should hesitate to dispense a prescription, the handwriting of which is so imperfect as to render the writer’s meaning doubtful—especially if it involves agents of a poisonous or irritating character—unless he is able, from collateral circumstances, to satisfy himself of the intent of the prescriber. In such a case he should delay the delivery of the medicine to the patient until he can see the physician, and in doing so he should avoid committing the latter, by agreeing to send the medicine when it is ready.

2d. The apothecary is justified in the same means of delay, if he, after deliberate consideration, believes that the physician has inadvertently made a mistake in the quantity or dose of the article or articles prescribed; always keeping in view the physician’s reputation as well as his own. Every respectful application, in such cases, to a physician, should be met in good faith {55} and with kind feeling, even though no error should prove to exist.

3d. In his demeanor and language, the apothecary should cautiously avoid compromising the physician, unless it be unavoidable, in which case honesty is the best policy, and the patient or his messenger should be told that it will be necessary to have an interview with the physician previously to compounding his prescription.

4th. The apothecary is not justifiable in making inquiries relative to the patient or his disease, or remarks relative to the character or properties of the medicines prescribed, that are uncalled for, or likely to convey a wrong impression, through an ignorant messenger, to the patient, excepting it be done in a case where he has doubts in regard to the prescription, and wishes to satisfy himself, and here he should act with great discreetness.

5th. When an apothecary is asked his opinion of a physician’s prescription in a manner that indicates want of faith in the prescriber, he should waive the question, unless by a direct answer he should be able to restore that confidence. When asked the nature of the ingredients, he should be guided in his answer by circumstances, avoiding to give the desired information, when he believes it would be contrary to the wish of the physician, or attended with injurious consequences. In other cases he should use his own judgment.

6th. Physicians being often unacquainted with practical pharmacy, pay little attention to the order in which the several articles entering into a prescription are arranged, with the view to facilitate the operations of dispensing. It hence becomes the first duty of the apothecary carefully to read the prescription and fix the proper order in his mind. He should, at the same time, acquire the habit of considering the quantities ordered in relation to the usual doses, and, also, the general bearing of the prescription; and a constant resort to this practice, based on due knowledge, must almost inevitably detect mistakes, if any have been made. {56}

7th. Apothecaries should accustom their assistants to study prescriptions in this light, and to acquire such a knowledge of the doses and therapeutical uses of medicines as shall serve to guide them in avoiding errors.

8th. The apothecary, when engaged in dispensing a prescription, should, as far as possible, avoid mental preoccupation, and give his attention fully to his task. He should acquire the habit of _always_ examining the label of the bottle before using its contents, and he should satisfy himself that he has read the prescribed quantity correctly, by referring to the prescription anew before weighing out each article. It is also, a useful precaution to have bottles containing mineral or vegetable poisons, distinguished by some prominent mark.

9th. As the conscientious discharge of his duty should be the aim of every apothecary, seeing that on his correct action depends, in no slight degree, the usefulness of the physician, no pains should be spared to secure the efficiency of the medicines dispensed, whether they be drugs or preparations. The latter should always be prepared of full strength, and according to the formulæ recognized by the United States Pharmacopœia, unless when otherwise specially ordered.

10th. The apothecary should always label, and number correctly, all medicine dispensed by him on the prescription of a physician; he should, also, invariably, transcribe on the label, in a plain legible hand writing, the name of the patient, the date of the prescription, the directions intended for the patient, and the name or the initials of the prescriber.

11th. The original prescription should always be retained by the apothecary, whose warrantee it is, in case of error on the part of the prescriber. When a copy is requested, if, as in many instances, no objection can be urged, it should be a _fac simile_ in language and symbols, and not a translation.

12th. In no instance is an apothecary justifiable in leaving his business in charge of boys, or incompetent assistants—or in allowing such to compound prescriptions, excepting under his immediate and careful supervision. {57}

13th. In justice to his sense of the proper limits of his vocation, to the medical profession, and to his customers, the apothecary should abstain from prescribing for diseases, excepting in those emergencies, which occasionally occur, demanding immediate action, or, in those every day unimportant cases where to refuse council would be construed as a confession of ignorance, calculated to injure the reputation of the apothecary, and would be attended with no advantage to either physician or patient.

14th. The sale of quack or secret medicines, properly so called, constitutes a considerable item in the business of some apothecaries. Many of the people are favorably impressed towards that class of medicines, and naturally go to their apothecaries for them. It is this which has caused many apothecaries to keep certain of these nostrums, who are ready and willing to relinquish the traffic in them, but for the offence that a refusal to supply them to their customers would create. At present all that the best disposed apothecary can be expected to do, is to refrain from the manufacture himself, of quack and secret medicines; to abstain from recommending them, either verbally or by exhibiting show bills, announcing them for sale, in his shop or windows; and to discourage their use, when appealed to.

15th. Having in view the welfare of the community and the advancement of pharmaceutic science and interest, it is all important that the offices of prescribing and compounding medicines should be kept distinct, in this city and surrounding districts. All connection with, or moneyed interest in apothecary stores, on the part of physicians, should, therefore, be discountenanced. With respect to the pecuniary understanding said to exist, in some instances, between apothecaries and physicians, we hold, that no well disposed apothecary or physician would be a party to such contract, and consider the code of Ethics of the College of Pharmacy and the Constitution of the Philadelphia County Medical Society as sufficiently explicit on this subject. {58}

16th. In reference to the patronage on the part of Physicians of particular apothecaries, we are of opinion, as a general rule, that Graduates in Pharmacy should be encouraged in preference to others of the same date of business, and whilst admitting the abstract right of the physician to send his prescription where he pleases, we think that justice should dictate the propriety of his encouraging the nearest apothecary deserving of his confidence and that of the patient.

_Committee of County Medical Society:_
D. FRANCES CONDIE,
WM. MAYBURY,
G. EMERSON.

_Committee of Phila. College of Pharmacy:_
WILLIAM PROCTER, JR.,
H. C. BLAIR,
JOHN H. ECKY.

[We republish the above Report from the American Journal of Pharmacy, as its “hints” are, in the main, practical and judicious. On one or two points, however, we differ from the author of the report. We do not think (B. Article 4th,) that the apothecary is ever justified in making inquiries relative to the disease of a patient. If his very inquiries may “convey a wrong impression to the patient, through an ignorant messenger,” how can that ignorant messenger give information regarding the disease of a patient, which can guide the apothecary, himself not supposed to be versed in therapeutics, in judging of the correctness of a prescription? The apothecary, where he is in doubt, may inquire the dose and the age of the patient, and then, if he deems necessary, may have recourse to the physician himself. And in regard to the next article, when the apothecary is asked the “nature of the ingredients” in a prescription, it is wisest to refer the patient, _as a rule_, to the prescriber.]—ED. JOURNAL OF PHARMACY.

NOTE ON THE DIVISION OF GUM RESINS IN POTIONS, AND IN DIACHYLON PLAISTER.

At a recent meeting of the Society of Pharmacy, M. Poulenc, submitted a method which he has employed for eight years in his laboratory, for suspending gum resins in medical prescriptions. It is well known how much difficulty there is in suspending either in a mixture, or lotion, one or more grammes of gum ammoniac, assafœtida, myrrh, &c. In dividing the {59} assafœtida with yolk of egg alone, the manipulation is long; but if instead of the egg, we employ 6 or 8 drops of oil of sweet almonds per gramme, the gum resin, even when entire, is easily reduced; when the oil is well mixed, and the paste as homogeneous as possible, a little water is first added, then gradually the quantity of the prescribed vehicle, as for the mucilage of a linctus; the product of this operation will be a speedy and very perfect emulsion. One of the advantages of this _modus faciendi_, is, that the product can be warmed without danger of coagulation, besides which, it is generally more easy to obtain a few drops of oil of sweet almonds, or any other kind of oil than the yolk of an egg.

M. Poulenc has recently applied the same method to the manufacture of diachylon plaister, in the following manner: take some entire pieces of gum resin, and triturate them briskly in an iron mortar, after which in a marble, or porcelain mortar, mix in the oil, and add a sufficient quantity of water to obtain an emulsion about as thick as liquid honey; strain this through a coarse cloth; there will be hardly anything left on the cloth, and the strained substance will be perfectly homogeneous. Evaporate in an earthen vessel, by the water-bath, the water which had been mixed in, and when the mass presents the appearance of a soft extract, the other ingredients of the plaister may be mixed in with the greatest ease. This plaister presents a very beautiful appearance, and exhales a very decided odour of the gum resins employed in its composition. Should it be feared that the small quantity of oil, might weaken the consistence of the plaister, M. Poulenc thinks that the quantity of turpentine might, without inconvenience, be slightly diminished.

We have tried with success the method of M. Poulenc for emulsions with gum resins; as to its further use in the preparation of diachylon plaister, we cannot speak with certainty.—There is a chemical question, which, in all cases governs the preparation of pharmaceutical agents.—_Stan. Martin, L’Abeille Medicale._

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ESSENCE OF JARGONELLE PEAR.

BY THE EDITOR OF THE PHARMACEUTICAL JOURNAL.

The liquid sold under this name, and which has been for some time in use by confectioners, is the _acetate of the oxide of amyle_.

It is prepared with great facility by submitting to distillation a mixture of one part of amylic alcohol (better known by the name of oil of grain,) two parts of acetate of potash, and one part of oil of vitriol. The distilled liquid is to be washed with alkaline water, dehydrated by chloride of calcium, and afterwards rectified by distillation from protoxide of lead.

Its properties are thus stated by Dumas:—In the state of purity it is a colorless, very limpid, volatile liquor, which boils at 257° F. It possesses an ethereal aromatic odor, somewhat resembling acetic ether; its sp. gr. is less than that of water. It is insoluble in water, but soluble in alcohol, ether, oil of grain, &c. Concentrated sulphuric acid does not color it in the cold; but by heating the mixture, it becomes reddish-yellow, and when the temperature is elevated, destructive reaction takes place, the mixture blackens and evolves sulphurous acid. Placed in contact with a watery solution of potash it is very slowly altered; but an alcoholic solution of this base rapidly decomposes, an alkaline acetate is formed, and the oil of grain regenerated. Its ultimate composition is

14 equivalents of carbon, 84
14 equivalents of hydrogen, 14
4 equivalents of oxygen, 32
───
130

But its proximate composition is amyle, (an hypothetical radical) oxygen, and acetic acid.

1 equivalent amyle (C‗{10} H‗{11}) 71 1 equivalent oxygen, 8 1 equivalent acetic acid, (C‗{4} H‗{3} O‗{3}) 51 ─── 130

Its formula is thus stated by Brande, AylO, AcO‗{3}; by Fownes, AylO, C‗{4} H‗{3} O‗{3}.

_Amylic alcohol_, or _oil of grain_, called by the Germans _fuselol_; is the hydrated oxide of amyle, AylO, HO. It is {61} largely produced in the distillation of spirit from corn. It is officinal in the Dublin Pharmacopœia, where it is termed “_Alcohol amylicum—Fusel oil_,” and is employed to yield valerianic acid in the process for making “Sodæ Valerianas.”

From information which we have received, we have reason to believe that the use, by very young children, of articles of confectionery, flavored with essence of pear, is not without danger. A child on two occasions became partially comatose, with livid lips and feeble pulse, after eating some confectionery which it was calculated contained about one drop of the essence.—_London Pharmaceutical Journal, November, ’51._

_On the Growth of Plants in Various Gases, Especially substituting Carbonic Oxide, Hydrogen, and light Carburetted Hydrogen for the Nitrogen of the Air._ By MESSRS. GLADSTONES. DR. GLADSTONE gave the results of experiments made and still in progress, with his brother, Mr. G. Gladstone. After describing the effect on some flowers, as the pansy, the crocus, &c.—a discussion ensued—Mr. R. Warrington suggesting that in such experiments the plants be allowed to take root well before immersing them in the gases; next, that the combined atmospheres were too much saturated with moisture, often causing rapid growth and decay; and that these flowers and roots should be compared with others grown in similar volumes of confined common air. Prof. Dumas spoke of the great, and, indeed, almost unsuspected influence of carbonic oxide gas. The judicial investigations in France had disclosed the fatal effects of this gas as being so much greater than carbonic acid gas. In the atmosphere produced by the burning of charcoal, 1-200th part of carbonic oxide was fatal, while with one-third the volume of carbonic acid the animal was asphyxiated, but afterwards revived. The Chairman said that he had reason to believe that in the combustion of anthracite, much carbonic oxide gas is produced.—_Pharmaceutic Journal, from Report of British Association in the Athenæum._

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EDITORIAL.

“AN ACT RELATING TO THE SALE OF DRUGS AND MEDICINES.”—We would call the attention of our readers to the following strange bill, which has been introduced into the Legislature of this State:

“_The People of the State of New York, represented in Senate and Assembly, do enact as follows_:

SECTION 1st. It shall not be lawful for any Physician, Druggist, Apothecary, or any person or persons dealing in Drugs or Medicines, or engaged in preparing any compound to be given or administered as a medicine, to offer the same for sale without first affixing or attaching thereto, in a conspicuous manner, a written or printed recipe in the English language, stating the drug or drugs, medicine or medicines, or ingredients of which it is composed, together with the proportions of each.

SECTION 2. Any person or persons violating the preceding section of this Act, shall be considered guilty of a misdemeanor, and on conviction thereof shall be fined for each offence in a sum not less than ten dollars, nor exceeding one hundred dollars, or be imprisoned for a term not exceeding six months.

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New York Journal of Pharmacy, Volume 1 (of 3), 1852Chapter III: Front Matter (3)

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