Chapter VIII: Part 8

_Treatment of renal and ureteral calculi._--Treatment is not very successful, as only the smallest calculi can pass through the ureter and enter the bladder, and even if they should do so they are liable to a progressive increase there, so that later they may cause the symptoms of stone in the bladder. Fortunately, ordinary dairy, growing, or fattening cattle rarely show evident symptoms of illness, and even though they do so they can usually be fattened and slaughtered before the health is seriously impaired. In work oxen the case is different, and acute symptoms may develop, but even then the animal may often be fitted for the butcher. When treatment is demanded it is primarily soothing and antispasmodic. Fomentations with warm water over the loins should be persisted in without intermission until relief has been secured. The soothing effect on the kidney will often relieve inflammation and irritation, should the stone be in that situation, while if in the ureter the warm fomentations will at once soothe irritation, relax spasm of the muscular coat of the canal, and favor an abundant secretion from the kidney, which, pressing on the obstructing stone, may slowly push it on into the bladder. Large doses of laudanum (2 ounces) or of solid extract of belladonna (2 drams) will not only soothe the pain but relax the spasm and favor the onward passage of the calculus. The animal should be encouraged to drink large quantities of cool water to favor the free secretion of a very watery urine, which will not only serve to obviate irritation and continued deposit caused by a highly concentrated urine, but will press the stone onward toward the bladder, and even in certain cases will tend to disintegrate it by solution of some of its elements, and thus to favor its crumbling and expulsion. This is a principle which must never be lost sight of in the treatment of calculi. The immersion of the stone in a liquid of a lower specific gravity than that in which it has formed and grown tends to dissolve out the more soluble of its component parts, and thus to destroy its density and cohesion at all points, and thereby to favor its complete disintegration and expulsion. This explains why cattle taken from a herd on magnesian limestone in spring, after the long, dry feeding of winter, usually have renal calculi, while cattle from the same herd in the fall, after a summer's run on a succulent pasture, are almost always free from concretions. The abundance of liquid taken in the green feed and expelled through the kidneys and the low density or watery nature of the urine have so opened the texture and destroyed the density of the smaller stones and gravel that they have all been disintegrated and removed. This, too, is the main reason why benefit is derived from a prolonged stay at mineral springs by the human victims of gravel. If they had swallowed the same number of quarts of pure water at home and distributed it at suitable times each day, they would have benefited largely without a visit to the springs.

It follows from what has been just said that a succulent diet, including a large quantity of water (gruels, sloppy mashes, turnips, beets, potatoes, apples, pumpkins, ensilage, succulent grasses), is an important factor in the relief of the milder forms of stone and gravel.

_Prevention._--Prevention of calculus especially demands this supply of water and watery rations on all soils and in all conditions in which there is a predisposition to the disease. It must also be sought by attempts to obviate all those conditions mentioned above as causative of the malady. Sometimes good rain water can be furnished in limestone districts, but putrid or bad-smelling rain water is to be avoided as probably more injurious than that from the limestone. Unsuccessful attempts have been made to dissolve calculi by alkaline salts and mineral acids, respectively, but their failure as a remedy does not necessarily condemn them as preventives. One dram of caustic potash or of hydrochloric acid may be given daily in the drinking water. In diametrically opposite ways these attack and decompose the less soluble salts and form new ones which are more soluble and therefore little disposed to precipitate in the solid form. Both are beneficial as increasing the secretion of urine. In cases in which the diet has been too highly charged with phosphates (wheat bran, etc.), these aliments must be restricted and water allowed ad libitum. If the crystals passed with the urine are the sharp angular (octahedral) ones of oxalate of lime, then the breathing should be made more active by exercise, and any disease of the lungs subjected to appropriate treatment. If the crystals are triangular prisms of ammonia-magnesium phosphate or starlike forms with feathery rays, the indications are to withhold the feed or water that abounds in magnesia and check the fermentation in the urine by attempts to destroy its bacteria. In the latter direction plenty of pure-water diuretics, and a daily dose of oil of turpentine in milk, or a dose thrice a day of a solution containing one-tenth grain each of biniodid of mercury and iodid of potassium would be indicated.

In considering the subject of prevention, it must never be forgotten that any disease of a distant organ which determines the passage from the blood into the urine of albumin or any other colloid (uncrystallizable) body is strongly provocative of calculus, and should, if possible, be corrected. Apart from cases from geological formation, faulty feeding, and other causes, the grand preventive of calculus is a long, summer's pasturage of succulent grasses, or in winter a diet of ensilage or other succulent feed.

The calculi formed in part of silica demand special notice. This agent is secreted in the urine in the form of silicate of potash and is thrown down as insoluble silica when a stronger acid displaces it by combining with the potash to its exclusion. In cases of siliceous calculi, accordingly, the appropriate chemical prevention is caustic potash, which being present in the free state would attract to itself any free acid and leave the silica in its soluble condition as silicate of potash.

STONE IN THE BLADDER (VESICAL CALCULUS, OR URETHRAL CALCULUS).

Stone in the bladder may be of any size, but in the ox does not usually exceed half an inch in diameter. There may, however, be a number of small calculi; indeed, they are sometimes so small and numerous as to form a small, pulpy magma by which the bladder is considerably distended.

_Symptoms._--The symptoms of stone in the bladder may be absent until one of the masses escapes into the urethra, but when this occurs the escape of urine is prevented, or it is allowed to pass in drops or driblets only, and the effect of such obstruction becomes manifest. The point of obstruction is not always the same, but it is most frequently at the S-shaped curve of the penis, just above the testicles or scrotum. In cows and heifers the urethra is so short and becomes so widely dilated during the urination that the calculi easily escape in the flow of liquid and dangerous symptoms practically never appear.

Even in the male the signs of illness are at first very slight. A close observer may notice the cylinders of hard, earthy materials encircling the tufts of hair at the opening of the prepuce. It may further be observed that the stall remains dry and that the animal has not been seen to pass water when out of doors. The tail may at times be gently raised and contractions of the muscle (accelerator urinÊ) beneath the anus (Pl. IX, fig. 2) may take place in a rhythmical or pulsating manner. As a rule, however, no symptom is noticed for two days, only the animal is lacking in his usual spirits. By this time the constantly accumulating urine has distended the bladder beyond its power of resistance and a rupture occurs, allowing the urine to escape into the cavity of the abdomen. Then dullness increases; the animal lies down most of his time; he becomes stupid and sometimes drowsy, with reddish-brown congestion of the lining membrane of the eyelids; pressure on the abdomen causes pain, flinching, and perhaps groaning, and the lowest part of the belly fluctuates more and more as the escaping urine accumulates in greater and greater amount. If at this stage the oiled hand is introduced into the rectum (last gut), the animal flinches when pressure is made downward on the floor of the pelvis, and no round, distended bladder is felt. If the same examination is made prior to the rupture, the rounded, tense, elastic bladder is felt extending forward into the abdomen, containing one or two gallons of liquid. There may be uneasy shifting of the hind limbs and twisting of the tail, also frequent lying down and rising, but these symptoms are exceptional.

When the obstruction is low down between the thighs (at the S-shaped flexure), the line of the pulsating urethra from the anus downward may be felt distended with liquid, and though, by the hard swelling of the urethra, it is seldom easy to distinguish the exact seat of the stone, yet there is usually tenderness at the point of obstruction, and from this it may be accurately located.

_Treatment._--The treatment of stone in the bladder or urethra consists in the removal of the stone by incision and the use of forceps. (Pl. XI, fig. 4.) When the stone has been arrested at the S-shaped flexure just above the scrotum, the patient being lean, the thickened tender part of the penis may be seized between the fingers and thumb of the left hand, while the calculus is exposed by a free incision with the knife held in the right. If there is no other obstruction between this point and the bladder, and if the latter has not yet ruptured, a flow of urine should take place from the opening. If there is no escape of liquid, a catheter or sound, one-fourth of an inch in diameter, must be passed up through the canal (urethra) until it is arrested by the next stone, on which a similar incision should then be made to effect its extraction. In case the stone has been arrested in the portion of the urethra which is in front of the arch of the hip bone and inside the pelvis, it can be reached only by making an opening into the urethra beneath the anus and over the arch of the hip bone, and from this orifice exploring the urethra with fine forceps to the neck of the bladder or until the stone has been reached and extracted. Owing to the small size of the canal (urethra) to be opened and the great thickness of erectile tissue to be cut through, the operation requires a very accurate knowledge of the parts, while the free flow of blood is blinding to the operator. A staff should always be passed up through the urethra from the lower wound, if such has been made, or, in case of its absence, through the whole length of the penis, that organ having been drawn out of its sheath until the S-shaped curve has been effaced and the course of the canal rendered straight. Upon the end of this staff the incision can be made with far more confidence and certainty. The operation can be undertaken only by a skilled veterinary anatomist, but the hints given above may be valuable in showing the stock owner when he is being properly served in such a case.

In outlying districts, where no skilled operator can be had, a transverse incision may be made with a clean, sharp knife through the root of the penis, just over the arch of the hip bone, when the urine will flow out in a full stream. The attendant bleeding may be ignored, or if profuse it may be checked by packing the wound firmly with cotton wool for several hours. The urine will continue to escape by the wound, and the ox should be fattened for the butcher.

The immediate relief is not to be looked upon as a permanent cure, as the calculi in the affected ox are usually numerous, and later attacks are therefore to be looked for. Hence it is desirable to fatten and kill such cases after a successful operation. If a breeding animal is too valuable to be killed, he should be subjected to preventive measures, as laid down under "Stone in the kidney," page 139.

It should be added that when the bladder is filled with a soft magma a catheter may be introduced through the whole length of the urethra to be used in pumping water into the bladder. This water is extracted through the same channel when it has been charged with the suspended solids by manipulations of the bladder with the oiled hand introduced through the rectum.

CALCULI, OR GRAVEL, IN THE PREPUCE, OR SHEATH.

This is usually a collection of gravel, or a soft, puttylike material which causes distinct swelling of the sheath and gives it a soft, doughy feeling when handled. It may be removed in part by the oiled fingers introduced into the cavity, assisted by manipulation from without, or a tube may be inserted until the end extends behind the collection and water pumped in until the whole mass has been evacuated. Should even this fail of success, the sheath may be slit open from its orifice back in the median line below until the offending matter can be reached and removed. In all such cases the interior of the sheath should be finally lubricated with sweet oil or vaseline. It is unnecessary to stitch up the wound made in the sheath. (See "Inflammation of the sheath," p. 155.)

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DISEASES OF THE URINARY ORGANS. DESCRIPTION OF PLATES.

PLATE IX. Kidney and male generative and urinary organs.

Fig. 1. Kidney of the ox. (From Handbuch des Vergleichenden Anatomie des Haus S‰ugethiere, vol. 7, 1890.) A, renal artery carrying blood into the kidney; V, renal vein carrying blood from the kidney back to the heart; H, ureter, the tube carrying the urine from kidney to bladder. It is formed by the union of a number of branches which begin as cups (calices), each inclosing the tip of a conical mass of tissue from which the urine excludes.

Fig. 2. Genital and urinary organs of the bull. (From Leisering, Mueller, and Ellenberger, Handbuch des Verg. Anat. des Haus S‰ugethiere.) the serous membrane enveloping the testicles; 3, the right testicle, outer view; 3', left testicle, inner view; 4, epididymis, or the beginning of the excretory canal of the testicle; 4', globus major, or the head of the epididymis; 4'', globus minor, or the tail of the epididymis; 5, vas deferens, the duct through which the seminal fluid reaches the ejaculatory ducts; 5', pelvic dilation of the vas deferens; 6, vesicula seminalis. The vesiculÊ seminalis are two oval pouches, which, in addition to their own secretions, receive the semen conveyed by the seminal ducts and hold it in reserve until copulation; 7, membranous or intrapelvic portion of the urethral canal covered by Wilson's muscle; 8, part of the prostate gland, covered by Wilson's muscle; 9, Cowper's gland. This gland, like the prostate gland, secretes a fluid which is thrown into the urethal canal in abundance immediately before ejaculation; by this means the expulsion of the semen is facilitated; 10, ejaculator seminis, or accelerator urinÊ muscle; 11, penis; 11', cut portion of same; 12, cut suspensory ligaments of penis; 13, sheath, or prepuce laid open; 14, retractor muscles of sheath; 15, cremaster muscle cut at superior extremity; 16, duplicature of peritoneum; 17, ureters carrying urine from the kidneys to the bladder.

PLATE X. Microscopic anatomy of the kidney.

Fig. 1. In this figure the minute apparatus for the secretion, collection, and discharge of the urine into the pelvis of the kidney (see preceding plate) is shown. The course is as follows: The urine is secreted from the blood vessels in the little round bodies called glomeruli (12), and by the minute cells in the curved tubes (11, 9, 10, 8), and passes through the convoluted and straight tubes (7, 6) into the larger tube (1), and then out into the pelvis, thence through the ureters into the bladder. The fluid and salts dissolved in the urine are taken from the blood, and the minute blood vessels are therefore very abundant in the kidneys, as is shown by the branches and network on the left of the figure. The blood passes into the kidney in the artery (13), which then divides into branches which pass into the glomeruli (12) and also forms network around the secreting tubules (11, 9). The urine and salts pass from these vessels through the cells lining the tubules into the latter, and are discharged as described above. The blood is again collected in veins drawn black in the figure.

Fig. 2 illustrates the manner in which the blood is distributed in the glomerulus (_f_), and also to the secreting tubules (_e_).

Fig. 3 shows the relation between the blood vessel in the glomerulus (_e_) the tubule which conducts the urine therein secreted from the blood vessel; (_c_) represents a glomerulus from which the urinary tubule has been removed.

PLATE XI. Calculi of kidney and bladder.

Fig. 1. Calculus, or stone, from the kidney. These are in the pelvis or portion of the ureter receiving the urine. The prolongations are casts of the branches of the pelvis. See the plates of the kidney for further description.

Fig. 2. Calculus made up of oxalate of lime magnified 215 times.

Fig. 3. Phosphatic calculus containing a nucleus of uric acid, sawed through to show concentric layers.

Fig. 4. Straight forceps used in removing stones from the bladder.

Fig. 5. Casts of the minute tubules of the kidney found in the urine in various kinds of kidney disease. Highly magnified.

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CALCULI OF KIDNEY AND BLADDER.]

FOOTNOTES:

[1] Encyklop. der Thierheilk., Vol. IV, p. 208.

DISEASES OF THE GENERATIVE ORGANS.

By JAMES LAW, F. R. C. V. S.,

_Formerly Professor of Veterinary Science, etc., in Cornell University._

[Revised by Adolph Eichhorn, D. V. S.]

GENERAL DISCUSSION.

Diseases of the generative organs are practically confined to animals which are kept for reproduction and the dairy. The castration of the bull condemns these organs to inactivity and protects them from the many causes of injury attendant on the engorged blood vessels in the frequent periods of sexual excitement, on the exposure to mechanical violence, and on the exposure to infective inoculation. In three respects the castrated male is especially subject to disease: (1) To inflammation and tumefaction of the cut end of the cord that supported the testicle and of the loose connective tissue of the scrotum; (2) to inflammation of the sheath and penis from the accumulation of gravel in the former, from which the penis is not usually protruded in passing water; and (3) to bruising, abrasion, and inflammation of the sheath and penis during suspension in the stocks for the purpose of shoeing. Apart from these the ox is practically almost exempt from the inflammations and injuries of the genital organs. The same applies to the castrated heifer. Inflammation may occur in the broad ligament of the womb whence the ovary has been removed or infective inflammation in the abdominal cavity (peritonitis) in case the operation has been performed through the flank, as it usually is in the young heifer. Apart from these, the castrated heifer is practically immune from any trouble of the generative apparatus. Even the virgin heifer is little subject to such troubles, though she is not exempt from inflammations, and above all, from morbid growths in the ovaries which are well developed and functionally very active after the first year, or in precocious animals after the first few months of life. The breeding cow, on the other hand, is subjected to all the disturbances attendant on the gradual enlargement of the womb, the diversion of a large mass of blood to its walls, the constant drain of nutrient materials of all kinds for the nourishment of the fetus, the risks attendant and consequent on abortion and parturition, the dangers of infection from the bull, the risks of sympathetic disturbance in case of serious diseases of other organs, but preeminently of the urinary organs and the udder, and finally the sudden extreme derangements of the circulation and of the nervous functions which attend on the sudden revulsion of a great mass of blood from the walls of the contracting womb into the body at large immediately after calving.

In reviewing this class of diseases, therefore, we have to note, first, that they are almost exclusively restricted to breeding animals, and secondly that in keeping with the absolute difference of the organs in the male and female we find two essentially distinct lists of diseases affecting the two sexes.

EXCESS OF VENEREAL DESIRE (SATYRIASIS IN MALE, OR NYMPHOMANIA IN FEMALE).

This may occur in the male from too frequent sexual intercourse, or from injury and congestion of the base of the brain (vasodilator center in the medulla), or of the posterior end of the spinal cord, or it may be kept up by congestion or inflammation of the testicles or of the mucous membrane covering the penis. It may be manifested by a constant or frequent erection, by attempts at sexual connection, and sometimes by the discharge of semen without connection. In bad cases the feverishness and restlessness lead to loss of flesh, emaciation, and physical weakness.

It is, however, in the female especially that this morbid desire is most noticeable and injurious. It may be excited by the stimulating quality of the blood in cows fed to excess on highly nitrogenous feed, as the seeds of the bean, pea, vetch, and tare, and as wheat bran, middlings, cotton seed, gluten meal, etc., especially in the case of such as have no free exercise in the fields, and are subject to constant association with a vigorous young bull. A more frequent cause is the excitation or congestion of some part of the genital organs. Disease of the ovaries is preeminently the cause, and this may be by the formation of cysts (sacs containing liquid) or of solid tumors or degenerations, or, more commonly than all, the formation of tubercle. Indeed, in case of tuberculosis attacking the abdominal organs of cows, the ovaries or the serous membranes that support and cover them (the broad ligaments of the womb) are peculiarly subject to attack, and the animal has constant sexual excitement, incessantly riding or being ridden by other cattle, having no leisure to eat or chew the cud, but moving restlessly, wearing the flesh off its bones, and gradually wasting. In some localities these cows are known as "bullers," because they are nearly always disposed to take the bull, but they do not conceive, or, if they do, they are subject to early abortions. They are, therefore, useless alike for the dairy and for the feeder, unless the removal of the ovaries subdues the sexual excitement, when, in the absence of tuberculous disease elsewhere, they may be fattened for the butcher.

Among the other sources of irritation charged with causing nymphomania are tumors and cancers of the womb, rigid closure of the neck of the womb so that conception can not occur and the frequent services by the male which stimulate the unsatisfied appetite, inflammation, and a purulent discharge from the womb or vagina.

_Treatment._--The treatment in each case will vary with the cause and is most satisfactory when that cause is a removable one. Overfeeding on richly nitrogenous feed can be stopped, exercise in the open field given, diseased ovaries may be removed (see "Castration," p. 299), catarrhs of the womb and passages overcome by antiseptic, astringent injections (see "Leucorrhea," p. 224), and tumors of the womb may often be detached and extracted, the mouth of that organ having been first dilated by sponge tents or otherwise. The rubber dilator (impregnator), sometimes helpful in the mare, is rarely available for the cow, owing to the different condition of the mouth of the womb.

DIMINUTION OR LOSS OF VENEREAL DESIRE (ANAPHRODISIA).

This occurs in either sex from low condition and ill health. Longstanding, chronic diseases of important internal organs, leading to emaciation and weakness, or a prolonged semistarvation in winter may be sufficient cause. It is, however, much more common as the result of degeneration or extensive and destructive disease of the secreting organs (testicles, ovaries) which elaborate the male and female sexual products, respectively. Such diseases are, therefore, a common cause of sterility in both sexes. The old bull, fat and lazy, becomes sluggish and unreliable in serving, and finally gets to be useless for breeding purposes. This is not attributable to his weight and clumsiness alone, but largely to the fatty degeneration of his testicles and their excretory ducts, which prevents the due formation and maturation of the semen. If he has been kept in extra high condition for exhibition in the show ring, this disqualification comes upon him sooner and becomes more irremediable.

Similarly the overfed, inactive cow, and above all the show cow, fails to come in heat at the usual times, shows little disposition to take the bull, and fails to conceive when served. Her trouble is the same in kind, namely, fatty degeneration of the ovaries and of their excretory ducts (Fallopian tubes), which prevents the formation or maturation of the ovum or, when it has formed, hinders its passage into the womb. Another common defect in such old, fat cows is a rigid closure of the mouth of the womb, which prevents conception, even if the ovum reaches the interior of that organ and even if the semen is discharged into the vagina.

_Preventive._--The true preventive of such conditions is to be found in a sound hygiene. The breeding animal should be of adult age, neither overfed nor underfed, but well fed and moderately exercised; in other words, the most vigorous health should be sought, not only that a strong race may be propagated, but that the whole herd, or nearly so, may breed with certainty. Fleming gives 79 per cent as the general average of cows that are found to breed in one year. Here more than a fifth of the progeny is sacrificed and a fifth of the product of the dairy. With careful management the proportion of breeders should approach 100 per cent. The various local and general obstacles to conception should be carefully investigated and removed. The vigorous health which comes from a sufficiently liberal diet and abundant exercise should be solicited, and the comparative bloodlessness and weakness which advance with undue fattening should be sedulously avoided. In bull or cow which is becoming unduly fat and showing indications of sexual indifference, the treatment must be active. Turning out on a short pasture where it must work hard for a living will often suffice. The bull which can not be turned out to pasture may sometimes be utilized in the yoke or tread power, or he may be kept a part of his time in a field or paddock chained by the ring in his nose to a strong wire extending from one side of the lot to the other and attached securely to two trees or posts. The wire should be higher than the back of the bull, which will move frequently from end to end. If he is indisposed to take sufficient exercise in this way he may be safely driven. An instance of the value of the exercise in these incipient cases of fatty degeneration is often quoted. The cow Dodona, condemned as barren at Earl Spencer's, was sold cheap to Jonas Webb, who had her driven by a road a distance of 120 miles to his farm at Wilbraham, soon after which she became pregnant. In advanced cases, however, in which the fatty degeneration is complete, recovery is impossible.

In case of rigid closure of the mouth of the womb the only resort is dilatation. This is far more difficult and uncertain in the cow than in the mare. The neck of the womb is longer, is often tortuous in its course, and its walls so approximated to each other and so rigid that it may be all but impossible to follow it, and there is always danger of perforating its walls and opening into the cavity of the abdomen, or, short of that, of causing inflammation and a new, rigid, fibrous formation which on healing leaves matters worse than before. The opening must be carefully made with the finger, and when that has entered the womb further dilatation may be effected by inserting a sponge tent or by careful stretching with a mechanical dilator. (Pl. XX, fig. 6.)

STERILITY FROM OTHER CAUSES.

The questions as to whether a bull is a sure stock getter and whether a cow is a breeder are so important that it would be wrong to pass over other prominent causes of sterility. Breeding at too early an age is a common source of increasing weakness of constitution which has existed in certain breeds. Jerseys have especially been made the victims of this mistake, the object being to establish the highest milking powers in the smallest obtainable body which will demand the least material and outlay for its constant repair of waste. With success in this line there has been the counterbalancing disadvantage of impaired vigor, with too often lessened fertility as well as increased predisposition to disease. When the heifers of the race have for generation after generation been bred under a year old, the demand for the nourishment of the fetus is too great a drain on the immature animal, which accordingly remains small and stunted. As it fails to develop in size, so every organ fails to be nourished to perfection. Similarly with the immature bull put to too many cows; he fails to develop his full size, vigor, or stamina, and transfers his acquired weakness to his progeny. An increasing number of barren females and an increasing proclivity to abortions are the necessary results of both courses. When this early breeding has occurred accidentally it is well to dry up the dam just after calving, and to avoid having her served again until full grown.

Some highly fed and plethoric females seem to escape conception by the very intensity of the generative ardor. The frequent passage of urine, accompanied by contractions of the womb and vagina and a profuse secretion from their surfaces, leads to the expulsion of the semen after it has been lodged in the genital passages. This may be remedied somewhat by giving 1-1/2 pounds of Epsom salt a day or two before she comes in heat, and subjecting her at the same time to a spare diet. Should the excessive ardor of the cow not be controllable in this way, she may be shut up for a day or two, until the heat is passing off, when under the lessened excitement the semen is more likely to be retained.

The various diseases of the ovaries, their tubes, the womb, the testicles and their excretory ducts, as referred to under "Excess of venereal desire," are causes of barrenness. In this connection it may be said that the discharges consequent on calving are fatal to the vitality of semen introduced before these have ceased to flow; hence service too soon after calving, or that of a cow which has had the womb or genital passages injured so as to keep up a mucopurulent flow until the animal comes in heat, is liable to fail of conception. Any such discharge should be first arrested by repeated injections as for leucorrhea, after which the male may be admitted.

Feeding on a very saccharine diet, which greatly favors the deposition of fat, seems to have an even more direct effect in preventing conception during such regimen. Among other causes of barrenness are all those that favor abortion, ergoted grasses, smutty wheat or corn, laxative or diuretic drinking water, and any improper or musty feed that causes indigestions, colics, and diseases of the urinary organs, notably gravel; also savin, rue, cantharides, and all other irritants of the bowels or kidneys.

Hermaphrodites are barren, of course, as their sexual organs are not distinctively either male or female. The heifer born as a twin with a bull is usually hermaphrodite and barren, but the animals of either sex in which development of the organs is arrested before they are fully matured remain as in the male or female prior to puberty, and are barren. Bulls with both testicles retained within the abdomen may go through the form of serving a cow, but the service is unfruitful; the spermatozoa are not fully elaborated. So I have examined a heifer with a properly formed but very small womb and an extremely narrow vagina and vulva, the walls of which were very muscular, that could never be made to conceive. A post-mortem examination would probably have disclosed an imperfectly formed ovary incapable of bringing ova to maturity.

A bull and cow that have been too closely inbred in the same line for generations may prove sexually incompatible and unable to generate together, though both are abundantly prolific when coupled with animals of other strains.

Finally, a bull may prove unable to get stock, not from any lack of sexual development, but from disease of other organs (back, loins, hind limbs), which renders him unable to mount with the energy requisite to the perfect service.

CONGESTION AND INFLAMMATION OF THE TESTICLES (ORCHITIS).

This visually results from blows or other direct injuries, but may be the result of excessive service or of the formation of some new growth (tumor) in the gland tissue. The bull moves stiffly, with straddling gait, and the right or left half of the scrotum in which the affected testicle lies is swollen, red, and tender, and the gland is drawn up within the sac and dropped again at frequent intervals. It may be treated by rest; by 1-1/2 pounds Epsom salt given in 4 quarts of water; by a restricted diet of some succulent feed; by continued fomentations with warm water by means of sponges or rags sustained by a sling passed around the loins and back between the hind legs. The pain may be allayed by smearing with a solution of opium or of extract of belladonna. Should a soft point appear, indicating the formation of matter, it may be opened with a sharp lancet and the wound treated daily with a solution of a teaspoonful of carbolic acid in a half pint of water. Usually, however, when the inflammation has proceeded to this extent, the gland will be ruined for purposes of procreation and must be cut out. (See "Castration," p. 299.)

INFLAMMATION OF THE SHEATH.

While this may occur in bulls from infection during copulation and from bruises, blows, and other mechanical injuries, the condition is more common in the ox in connection with the comparative inactivity of the parts. The sheath has a very small external opening, the mucous membrane of which is studded with sebaceous glands secreting a thick, unctuous matter of a strong, heavy odor. Behind this orifice is a distinct pouch, in which this unctuous matter is liable to accumulate when the penis is habitually drawn back. Moreover, the sheath has two muscles (protractors) which lengthen it, passing into it from the region of the navel, and two (retractors) that shorten it, passing into it from the lower surface of the pelvic bones above. (Pl. IX, fig. 2.) The protractors keep the sheath stretched, so that it habitually covers the penis, while the retractors shorten it up in the act of service, so that the penis can project to its full extent. In stud bulls the frequent protrusion of the erect and enlarged penis and the retraction and dilation of the opening of the sheath serve to empty the pouch and prevent any accumulation of sebaceous matter or urine. In the ox, on the other hand, the undeveloped and inactive penis is usually drawn back so as to leave the anterior preputial pouch empty, so that the sebaceous matter has space to accumulate and is never expelled by the active retraction of the sheath and protrusion of the erect penis in service. Again, the ox rarely protrudes the tip of the penis in urination, the urine is discharged into the preputial pouch and lodges and decomposes there, so that there is a great liability to the precipitation of its earthy salts in the form of gravel. The decomposing ammoniacal urine, the gritty crystals precipitated from it, and the fetid, rancid, sebaceous matter set up inflammation in the delicate mucous membrane lining the passage. The membrane is thickened, reddened, rendered friable, and ultimately ulcerated, and the now narrowed sheath is blocked by the increasing mass of sebaceous and urinous material and the decomposing mucus and pus. The penis can no longer be protruded, the urine escapes in a small stream through the narrowing sheath, and finally the outlet is completely blocked and the urine distends the back part of the sheath. This will fluctuate on being handled, and soon the unhealthy inflammation extends on each side of it, causing a thick, doughy, tender swelling under the belly and between the thighs. The next step in the morbid course is overdistention of the bladder, with the occurrence of colicky pains, looking at the flanks, uneasy movements of the hind limbs, raising or twisting of the tail, pulsatory contractions of the urethra under the anus, and finally a false appearance of relief, which is caused by rupture of the bladder. Before rupture takes place the distended bladder may press on the rectum and obstruct the passage of the bowel dejections. Two mistakes are therefore probable--first, that the bowels alone are to be relieved, and, second, that the trouble is obstruction of the urethra by a stone. Hence the need of examining the sheath and pushing the finger into its opening to see that there is no obstruction there, in all cases of retention of urine, overdistended bladder, or blocked rectum in the ox. The disease may be acute or chronic--the first by reason of acute, adhesive inflammation blocking the outlet, the second by gradual thickening and ulceration of the sheath and blocking by the sebaceous and calculous accretion.

_Treatment._--The treatment of this affection depends on the stage. If recent and without instant danger of rupture of the bladder, the narrow opening of the sheath should be freely cut open in the median line below, and the sac emptied out with a finger or spoon, after which it should be thoroughly washed with tepid water. To make the cleansing more thorough a catheter or a small, rubber tube may be inserted well back into the sheath, and water may be forced through it from a syringe or a funnel inserted into the other end of the tube and considerably elevated. A fountain syringe, which should be in every house, answers admirably. The sheath may be daily washed out with tepid water, with a suds made with Castile soap, or with a weak solution of sulphate of zinc (one-half dram to a quart of water). If these attentions are impossible, most cases, after cleansing, will do well if merely driven through clean water up to the belly once a day.

In case the disease has progressed to absolute obstruction, with the bladder ready to rupture any moment, no time must be lost in opening into the urethra with a sharp knife over the bony arch under the anus, where the pulsations are seen in urinating. This incision is best made in the median line from above downward, but in the absence of a skillful operator a transverse incision with a sharp knife over the bone in the median line until the urine flows with a gush is better than to let the patient die. Considerable blood will be lost and the wound will heal tardily, but the ox will be preserved. Then the slitting and cleansing of the sheath can be done at leisure, as described above. If the bladder is ruptured, the case is hopeless.

INFLAMMATION OF THE SHEATH AND PENIS FROM BRUISING.

This also is an affection of work oxen, caused by the pressure and friction of the sling when the animals are held in stocks for shoeing. This crushing of both sheath and penis for half an hour or more leads to the development, some hours later, of a hard, hot, and painful swelling, extending from the scrotum as far as the opening of the sheath. Fever sets in, with dry muzzle, red eyes, hard, full, rapid pulse, accelerated breathing, and elevated temperature. The ox stands obstinately with his hind legs drawn apart and urine falling drop by drop from the sheath. Appetite and rumination are suspended. In twenty-four hours there may be indications of advancing gangrene (mortification), the swelling becomes cold, soft, and doughy; it may even crack slightly from the presence of gas; a reddish brown, fetid liquid oozes from the swelling, especially around the edges, and if the animal survives it is only with a great loss of substance of the sheath and penis.

_Prevention._--The prevention of such an injury is easy. It is only necessary to see that the slings do not press upon the posterior part of the abdomen. They must be kept in front of the sheath.

_Treatment._--Treatment, to be effective, must be prompt and judicious. Put around the patient a strap with soft pads in contact with the affected parts, constantly soaked in cold water for at least 24 hours. A pound or two of Epsom salt in 4 quarts of hot water should also be given. The second day the parts may be washed with 1 quart of witch-hazel (extract), 2 drams sugar of lead, and 1 ounce laudanum, or the cold-water irrigations may be continued if the active inflammation persists. In case the swelling continues hard and resistant, it may be pricked at the most prominent points to the depth of one-third of an inch with a lancet first dipped in dilute carbolic acid, and the whole surface should be washed frequently with some antiseptic solution.

When softening occurs in the center of a hard mass and fluctuation can be felt between two fingers pressed on different parts of such softening, it should be freely opened to let out the putrid pus, and the cavity should be syringed often with antiseptic solution.

In bad cases extensive sloughs of dead skin, of the whole wall of the sheath, and even of the penis, may take place, which will require careful antiseptic treatment. The soaking of the urine into the inflamed and softened tissue and the setting up of putrefactive action not only endanger great destruction of the tissues from putrid inflammation, but even threaten life itself from a general blood poisoning (septicemia). Every case should have skillful treatment to meet its various phases, but in the severe ones this is most urgently demanded.

INFLAMMATION OF THE URETHRA.

Like other males, the bull sometimes suffers from inflammation of the canal which conveys the urine through the penis, and a whitish mucopurulent discharge forms in consequence. It may have originated in gravel, the excitement of too frequent service, infection from a cow with leucorrhea, or from extension of inflammation from the sheath. Besides the oozing of the whitish liquid from the end of the penis and sheath, there is tenderness and pain when handled, and while there is no actual arrest of the urine, its flow is subject to frequent voluntary checks, as the scalding liquid irritates the tender surface.

_Treatment._--If recognized before the discharge sets in, a dose of 1-1/2 pounds of Epsom salt and local, warm fomentations would be appropriate. After the onset of the whitish discharge a daily injection of a solution of 20 grains of permanganate of potassium in a pint of water into the penis will be beneficial.

WARTS AND PAPILLARY GROWTHS ON THE PENIS.

These are not frequent in bull or ox. They may interfere with the protrusion of the organ from its sheath or with service, and always give rise to a bad-smelling discharge.

_Treatment._--They may be twisted off with a pair of small tweezers or cut off with a pair of scissors, and the seat burned with a pencil of lunar caustic. To get hold of the penis in the bull, bring him up to a cow. In the ox it will be necessary to push it out by manipulation through the sheath. In difficult cases the narrow opening of the sheath may be slit open.

WOUNDS OF THE PENIS.

The most common wounds are those sustained by blows of horns, sticks, etc. The blood vessels and sacs are ruptured to a greater or less extent and considerable swellings filled with coagulated blood and inflammatory products occur, leading to distortion of the organ, and it may be to the impossibility of protruding it.

_Treatment._--A lotion of a dram of alum in a quart of water may be applied (injected into the sheath, if necessary), and a large sponge constantly irrigated by a stream of cold water may be kept applied by means of a surcingle to the outer side of the sheath. Incisions are rarely applicable to an organ of this kind, but in case of the existence of an extensive clot which is unlikely to be absorbed the lancet may be resorted to. If the injury leads to paralysis of the penis and hanging out of its sheath, it should be supported in a sling and astringents used freely until inflammation subsides. Then the restoration of power may be sought by a blister between the thighs, by the use of electricity, or by the careful use of nerve stimulants, such as strychnin, 1 grain twice daily.

ULCERS ON THE PENIS.

Sores on the penis of the bull may result from gravel or sebaceous masses in the sheath or from having served a cow having leucorrhea.

_Treatment._--These may be treated by frequent injections into the sheath of a lotion made with 1 dram sugar of lead, 60 drops carbolic acid, and 1 quart water.

POLYPUS OF THE VAGINA OR UTERUS.

A polypus is a tumor growing from the mucous membrane, and often connected to it by a narrow neck. A definite cause can not always be assigned. If growing in the vagina, a polypus may project as a reddish, rounded tumor from the vulva, especially during the act of passing water. It can be distinguished from descent of the womb by the absence of the orifice of that cavity, which can be felt by the oiled hand beyond the tumor in the depth of the vagina. From a vaginal hernia caused by the protrusion of some abdominal organ enveloped by the relaxed wall of the vagina it may be distinguished by its persistence, its firm substance, and the impossibility of returning it into the abdomen by pressure. A hernia containing a portion of bowel gurgles when handled and can be completely effaced by pressure, the gut passing into the abdomen.

A polypus in the womb is less easily recognized. At the time of calving it may be felt through the open mouth of the womb and recognized by the educated touch (it must be carefully distinguished from the mushroom-formed cotyledons (Pl. XIII, fig. 2), to which in ruminants the fetal membranes are attached). At other times, unless the womb is opened in the effort to expel it, the polypus can be detected only by examining the womb with the oiled hand introduced through the rectum.

Polypi may cause a mucopurulent discharge or they may only be suspected when they prove an obstacle to parturition. The best way to remove them is to put the chain of an Ècraseur around the neck, or pedicle, of the tumor and tear it through; or the narrow neck may be torn through by the emasculator, or in an emergency it may be twisted through by rotating the tumor on its axis. The removal of the tumor will allow calving to proceed; after this the sore may be treated by a daily injection of one-half dram sulphate of zinc, 1 dram carbolic acid, and 1 quart milk-warm water.

SIGNS OF PREGNANCY.

If a cow remains for three or four weeks after service without showing signs of heat (bulling), she is probably pregnant. There are very exceptional cases in which the well-fed cow will accept the bull weeks or months after actual conception, and others equally exceptional in which the well-thriven but unimpregnated female will refuse the male persistently, but these in no way invalidate the general rule.

The bull, no matter how vigorous or how ardent his sexual instinct, can not be made to pay any attention to a cow which is not in heat; hence indications of pregnancy can be had from both the male and female side. When she has conceived, the cow usually becomes more quiet and docile, and lays on flesh and fat more rapidly, especially during the first four months of gestation. The stimulus to digestion and nutrition created by the demands of the growing fetus, added to the quieter and more uneventful life, contributes to this result. Some feeders avail themselves of this disposition to prepare heifers and cows speedily for the butcher.

The enlargement of the abdomen, and its dropping so that it bulges below and to each side, while it falls in at the flank, between the outer angle of the hip bone and the last rib, are significant features which, though they may be caused by abdominal tumor or dropsy, are usually marks of pregnancy. From the same increasing weight of the abdomen the spine in the region of the loins sinks so that the bones of the croup seem to rise, especially back toward the root of the tail. In the early stages of pregnancy the udder develops slowly, and toward its completion quite rapidly. For a long time there is merely a sense of greater fullness when handled; the wrinkles in the skin become shallower and are effaced, and the teats are materially enlarged. Beginning a few weeks after conception, this tends to a steady development, though slight alternations in the sense of successive growth and shrinkage are not uncommon. In milking cows this does not hold, as the milk usually tends to a steady diminution and the udder shrinks slowly until near the completion of the period, when it undergoes its sudden, remarkable development, and yields at first a serous liquid and then the yellow colostrum, which coagulates when heated. As pregnancy advances the mucous membrane lining the vulva becomes swollen and of a darker, bluish-red hue; the mucous secretion also increases, becoming very abundant just before calving. When the feeding has not been altered or restricted, a steady diminution of the salts of lime excreted in the urine is an attendant on pregnancy, the lime being demanded for the growing body of the fetus.

After the fifth month the movements of the calf may often be observed in the right flank, nearly in front of the stifle, when the cow is drinking cold water. The sensation of cold on the side of the first stomach, which lies to the left and directly below the womb (Pl. I), stimulates the calf to active movements, which are detected on the sudden jerking outward of the abdominal wall as if from blows delivered from within. In a loose, pendent abdomen in the latter months of gestation the skin may often be seen pushed out at a sharp angle, irrespective of the period of drinking.

Another mode of examination through the flank is by touch. The palm of the hand is pressed strongly inward, about 8 inches in front of the stifle and a little below, several times in succession, and is then brought to rest with the pressure maintained. Presently there are felt distinct and characteristic movements of the fetus, which has been disturbed and roused to action. Another mode is to press the closed fist strongly inward in the same situation and hold it so, forming a deep indentation in the abdominal wall. Presently the knuckles are felt to be struck by a solid body, which is no other than the fetus that has been displaced to the left by the push of the hand, and now floats back in its liquid covering (amniotic fluid; see Pl. XII) downward and to the right.